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Evaluating the Association of Clinical Characteristics With Neutralizing Antibody Levels in Patients Who Have Recovered From Mild COVID-19 in Shanghai, China

Evaluating the Association of Clinical Characteristics With Neutralizing Antibody Levels in... Key PointsQuestionAre clinical characteristics of patients who recovered from mild coronavirus disease 2019 (COVID-19) associated with levels of neutralizing antibodies? FindingsIn this cohort study of 175 patients who recovered from mild COVID-19, neutralizing antibody titers to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) varied substantially at the time of discharge. In addition, neutralizing antibodies were not detected in 10 patients. MeaningFurther research is needed to understand the implications of variable levels of SARS-CoV-2–specific neutralizing antibodies for protection against future infections with SARS-CoV-2. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Evaluating the Association of Clinical Characteristics With Neutralizing Antibody Levels in Patients Who Have Recovered From Mild COVID-19 in Shanghai, China

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References (24)

Publisher
American Medical Association
Copyright
Copyright 2020 Wu F et al. JAMA Internal Medicine.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/jamainternmed.2020.4616
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionAre clinical characteristics of patients who recovered from mild coronavirus disease 2019 (COVID-19) associated with levels of neutralizing antibodies? FindingsIn this cohort study of 175 patients who recovered from mild COVID-19, neutralizing antibody titers to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) varied substantially at the time of discharge. In addition, neutralizing antibodies were not detected in 10 patients. MeaningFurther research is needed to understand the implications of variable levels of SARS-CoV-2–specific neutralizing antibodies for protection against future infections with SARS-CoV-2.

Journal

JAMA Internal MedicineAmerican Medical Association

Published: Oct 18, 2020

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