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Key PointsQuestionIs the association of short interpregnancy interval with pregnancy outcomes modified by maternal age? FindingsIn this cohort study of 148 544 pregnancies, maternal mortality or severe morbidity risks were increased at short interpregnancy intervals among women 35 years or older but not for women aged 20 to 34 years; in contrast, increased risks of adverse fetal and infant outcomes and spontaneous preterm delivery were more pronounced for women aged 20 to 34 years than for those 35 years and older. Modest increases in risks of small-for-gestational-age birth and indicated preterm delivery at short intervals were not meaningfully different across maternal age groups. MeaningShort interpregnancy intervals appear to be associated with increased risks for adverse pregnancy outcomes for women of all ages; maternal risks at short intervals may be greater for older women, whereas fetal and infant risks may be greater for younger women.
JAMA Internal Medicine – American Medical Association
Published: Dec 29, 2018
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