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C. Aydin, N. Donaldson, N. Stotts, M. Fridman, D. Brown (2015)
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Letters 1. O’Donnell MJ, Yusuf S, Mente A, et al. Urinary sodium and potassium the dose-response association between sodium intake and 1,2 excretion and risk of cardiovascular events. JAMA. 2011;306(20):2229-2238. outcomes. On the other hand, limited precision does dilute 2. O’Donnell M, Mente A, Rangarajan S, et al; PURE Investigators. Urinary regression estimates, and this might have weakened the as- sodium and potassium excretion, mortality, and cardiovascular events. N Engl J sociation with the outcomes of interest in our study. We also Med. 2014;371(7):612-623. agree that statistical power was limited in the high sodium in- 3. Kalogeropoulos AP, Georgiopoulou VV, Murphy RA, et al. Dietary sodium take group. We categorized sodium intake using cutoff points content, mortality, and risk for cardiovascular events in older adults: the Health, Aging, and Body Composition (Health ABC) Study. JAMA Intern Med. 2015;175 driven by the current US recommendations to facilitate clini- (3):410-419. cal interpretation. We would have liked to analyze a very high 4. Umesawa M, Iso H, Date C, et al; JACC Study Group. Relations between sodium intake subgroup, but the number of participants was dietary sodium and potassium intakes and mortality from cardiovascular too small to provide stable estimates. The small
JAMA Internal Medicine – American Medical Association
Published: Sep 1, 2015
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