Access the full text.
Sign up today, get DeepDyve free for 14 days.
MR Patel, JH Calhoon, GJ Dehmer (2017)
ACC/AATS/AHA/ASE/ASNC/SCAI/SCCT/STS 2017 appropriate use criteria for coronary revascularization in patients with stable ischemic heart disease: a report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, and Society of Thoracic Surgeons, 69
Beltrame (2009)
1491Arch Intern Med, 169
Basch (2017)
197JAMA, 318
A. Laupacis, D. Sackett, R. Roberts (1988)
An assessment of clinically useful measures of the consequences of treatment.The New England journal of medicine, 318 26
J. Spertus, Jennifer Winder, T. Dewhurst, R. Deyo, J. Prodzinski, M. Mcdonnell, S. Fihn (1995)
Development and evaluation of the Seattle Angina Questionnaire: a new functional status measure for coronary artery disease.Journal of the American College of Cardiology, 25 2
S. Arnold, M. Kosiborod, Yan Li, Philip Jones, Patrick Yue, L. Belardinelli, J. Spertus (2014)
Comparison of the Seattle Angina Questionnaire With Daily Angina Diary in the TERISA Clinical TrialCirculation: Cardiovascular Quality and Outcomes, 7
J. Spertus, J. Spertus, Jennifer Winder, Jennifer Winder, T. Dewhurst, T. Dewhurst, R. Deyo, R. Deyo, S. Fihn, S. Fihn (1994)
Monitoring the quality of life in patients with coronary artery disease.The American journal of cardiology, 74 12
Spertus (2002)
43Circulation, 106
R. Al-Lamee, D. Thompson, H. Dehbi, S. Sen, K. Tang, J. Davies, Thomas Keeble, Michael Mielewczik, R. Kaprielian, I. Malik, S. Nijjer, R. Petraco, Christopher Cook, Y. Ahmad, J. Howard, C. Baker, A. Sharp, R. Gerber, S. Talwar, R. Assomull, J. Mayet, R. Wensel, D. Collier, M. Shun-shin, S. Thom, J. Davies, D. Francis, A. Sethi, P. Ramrakha, R. Foale, R. Khamis, N. Hadjiloizou, Masood Khan, J. Kooner, Michael Bellamy, G. Mikhail, P. Clifford, P. O'Kane, T. Levy, R. Swallow (2018)
Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trialThe Lancet, 391
S. Arnold, D. Morrow, Y. Lei, D. Cohen, E. Mahoney, E. Braunwald, P. Chan (2009)
Economic Impact of Angina After an Acute Coronary Syndrome: Insights From the MERLIN-TIMI 36 TrialCirculation: Cardiovascular Quality and Outcomes, 2
J. Spertus, B. Bliven, Michelle Farner, Amy Gillen, Traci Hewitt, Philip Jones, Ben McCallister (2001)
Integrating baseline health status data collection into the process of care.The Joint Commission journal on quality improvement, 27 7
Spertus (2005)
707Am Heart J, 150
Weintraub (2008)
677N Engl J Med, 359
Shafiq (2016)
94Am Heart J, 175
J. Spertus, Philip Jones, D. Maron, Sean O'Brien, H. Reynolds, Y. Rosenberg, G. Stone, F. Harrell, W. Boden, W. Weintraub, Khaula Baloch, K. Mavromatis, Ariel Diaz, G. Gosselin, J. Newman, Stavroula Mavromichalis, K. Alexander, D. Cohen, S. Bangalore, J. Hochman, D. Mark (2020)
Health-Status Outcomes with Invasive or Conservative Care in Coronary Disease.The New England journal of medicine
A. Malik, J. Spertus, M. Patel, G. Dehmer, K. Kennedy, P. Chan (2020)
Potential Association of the ISCHEMIA Trial With the Appropriate Use Criteria Ratings for Percutaneous Coronary Intervention in Stable Ischemic Heart Disease.JAMA internal medicine
J. Spertus, Philip Jones, M. McDonell, V. Fan, S. Fihn (2002)
Health Status Predicts Long-Term Outcome in Outpatients With Coronary DiseaseCirculation: Journal of the American Heart Association, 106
Laupacis (1988)
1728N Engl J Med, 318
Mohammed Qintar, J. Grantham, J. Sapontis, Kensey Gosch, W. Lombardi, D. Karmpaliotis, J. Moses, Adam Salisbury, David Cohen, J. Spertus, S. Arnold (2017)
Dyspnea Among Patients With Chronic Total Occlusions Undergoing Percutaneous Coronary Intervention: Prevalence and Predictors of ImprovementCirculation: Cardiovascular Quality and Outcomes, 10
Arnold (2014)
844Circ Cardiovasc Qual Outcomes, 7
Zefeng Zhang, E. Mahoney, R. Stables, J. Booth, F. Nugara, J. Spertus, W. Weintraub (2003)
Disease-Specific Health Status After Stent-Assisted Percutaneous Coronary Intervention and Coronary Artery Bypass Surgery: One-Year Results From the Stent or Surgery TrialCirculation: Journal of the American Heart Association, 108
Rose (1968)
1Monogr Ser World Health Organ, 56
S. Arnold, Paul Chan, Philip Jones, C. Decker, Donna Buchanan, H. Krumholz, P. Ho, J. Spertus (2011)
Translational Research Investigating Underlying Disparities in Acute Myocardial Infarction Patients' Health Status (TRIUMPH): Design and Rationale of a Prospective Multicenter RegistryCirculation: Cardiovascular Quality and Outcomes, 4
Mohammed Qintar, J. Spertus, Kensey Gosch, J. Beltrame, Faraz Kureshi, A. Shafiq, T. Breeding, K. Alexander, S. Arnold (2016)
Effect of angina under-recognition on treatment in outpatients with stable ischaemic heart disease.European heart journal. Quality of care & clinical outcomes, 2 3
Spertus (2020)
1408N Engl J Med, 382
Al-Lamee (2018)
1780Circulation, 138
Maron (2020)
1395N Engl J Med, 382
Qintar (2017)
Dyspnea among patients with chronic total occlusions undergoing percutaneous coronary intervention: prevalence and predictors of improvement.Circ Cardiovasc Qual Outcomes, 10
J. Beltrame, A. Weekes, C. Morgan, R. Tavella, J. Spertus (2009)
The prevalence of weekly angina among patients with chronic stable angina in primary care practices: The Coronary Artery Disease in General Practice (CADENCE) Study.Archives of internal medicine, 169 16
S. Rinfret, C. Grines, R. Cosgrove, K. Ho, D. Cox, B. Brodie, M. Morice, G. Stone, D. Cohen (2001)
Quality of life after balloon angioplasty or stenting for acute myocardial infarction. One-year results from the Stent-PAMI trial.Journal of the American College of Cardiology, 38 6
Qintar (2016)
208Eur Heart J Qual Care Clin Outcomes, 2
Chan (2014)
640Circ Cardiovasc Qual Outcomes, 7
K. Patel, S. Arnold, P. Chan, Yuanyuan Tang, Philip Jones, Jianping Guo, Donna Buchanan, Mohammed Qintar, C. Decker, D. Morrow, J. Spertus (2018)
Validation of the Seattle angina questionnaire in women with ischemic heart diseaseAmerican Heart Journal, 201
John Saxon, Paul Chan, Andy Tran, Suveen Angraal, Phillip Jones, J. Grantham, J. Spertus (2020)
Comparison of Patient-Reported vs Physician-Estimated Angina in Patients Undergoing Elective and Urgent Percutaneous Coronary InterventionJAMA Network Open, 3
Patel (2017)
2212J Am Coll Cardiol, 69
E. Basch, A. Deal, A. Dueck, H. Scher, M. Kris, C. Hudis, D. Schrag (2017)
Overall Survival Results of a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring During Routine Cancer TreatmentJAMA, 318
Spertus (2008)
2103Circulation, 118
Spertus (1994)
1240Am J Cardiol, 74
Spertus (1995)
333J Am Coll Cardiol, 25
Zhang (2003)
1694Circulation, 108
Pauly (2011)
678Am Heart J, 162
L. Goldman, B. Hashimoto, E. Cook, A. Loscalzo (1981)
Comparative Reproducibility and Validity of Systems for Assessing Cardiovascular Functional Class: Advantages of a New Specific Activity ScaleCirculation, 64
W. Weintraub, J. Spertus, P. Kolm, D. Maron, Zefeng Zhang, C. Jurkovitz, Wei Zhang, P. Hartigan, Cheryl Lewis, E. Veledar, J. Bowen, S. Dunbar, C. Deaton, Stanley Kaufman, R. O'rourke, R. Goeree, P. Barnett, K. Teo, W. Boden, G. Mancini (2008)
Effect of PCI on quality of life in patients with stable coronary disease.The New England journal of medicine, 359 7
R. McNamara, E. Spatz, T. Kelley, C. Stowell, J. Beltrame, P. Heidenreich, R. Tresserras, T. Jernberg, T. Chua, Louise Morgan, B. Panigrahi, Alba Ruiz, J. Rumsfeld, Lawrence Sadwin, M. Schoeberl, D. Shahian, C. Weston, R. Yeh, Jack Lewin (2015)
Standardized Outcome Measurement for Patients With Coronary Artery Disease: Consensus From the International Consortium for Health Outcomes Measurement (ICHOM)Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 4
Basch (2016)
557J Clin Oncol, 34
S. Arnold, A. Grodzinsky, Kensey Gosch, M. Kosiborod, Philip Jones, T. Breeding, Arooge Towheed, J. Beltrame, K. Alexander, J. Spertus (2016)
Predictors of Physician Under-Recognition of Angina in Outpatients With Stable Coronary Artery DiseaseCirculation: Cardiovascular Quality and Outcomes, 9
Arnold (2016)
554Circ Cardiovasc Qual Outcomes, 9
R Al-Lamee, JP Howard, MJ Shun-Shin (2018)
Fractional flow reserve and instantaneous wave-free ratio as predictors of the placebo-controlled response to percutaneous coronary intervention in stable single-vessel coronary artery disease, 138
Spertus (2001)
550Am Heart J, 141
Mouin Abdallah, Kaijun Wang, E. Magnuson, J. Spertus, M. Farkouh, V. Fuster, D. Cohen (2013)
Quality of life after PCI vs CABG among patients with diabetes and multivessel coronary artery disease: a randomized clinical trial.JAMA, 310 15
D. Maron, J. Hochman, H. Reynolds, S. Bangalore, Sean O'Brien, W. Boden, B. Chaitman, R. Senior, R. Senior, J. López-Sendón, K. Alexander, R. Lopes, L. Shaw, J. Berger, J. Newman, M. Sidhu, S. Goodman, W. Rużyłło, G. Gosselin, A. Maggioni, H. White, B. Bhargava, J. Min, G. Mancini, D. Berman, M. Picard, R. Kwong, Z. Ali, D. Mark, J. Spertus, M. Krishnan, A. Elghamaz, N. Moorthy, W. Hueb, M. Demkow, K. Mavromatis, O. Bockeria, J. Peteiro, Todd Miller, H. Szwed, R. Doerr, M. Keltai, J. Selvanayagam, P. Steg, C. Held, S. Kohsaka, Stavroula Mavromichalis, R. Kirby, N. Jeffries, F. Harrell, F. Rockhold, S. Broderick, T. Ferguson, David Williams, R. Harrington, G. Stone, Y. Rosenberg (2020)
Initial Invasive or Conservative Strategy for Stable Coronary Disease.The New England journal of medicine
Arnold (2008)
107Circ Cardiovasc Qual Outcomes, 1
G. Rose, H. Blackburn (1969)
Cardiovascular survey methods.Monograph series. World Health Organization, 56
Arnold (2009)
344Circ Cardiovasc Qual Outcomes, 2
Arnold (2011)
467Circ Cardiovasc Qual Outcomes, 4
S. Arnold, D. Morrow, Kaijun Wang, Y. Lei, E. Mahoney, B. Scirica, E. Braunwald, D. Cohen (2008)
Effects of Ranolazine on Disease-Specific Health Status and Quality of Life Among Patients With Acute Coronary Syndromes: Results from the MERLIN-TIMI 36 Randomized TrialCirculation: Cardiovascular Quality and Outcomes, 1
E. Basch, A. Deal, M. Kris, H. Scher, C. Hudis, P. Sabbatini, L. Rogak, A. Bennett, A. Dueck, T. Atkinson, J. Chou, Dorothy Dulko, L. Sit, A. Barz, P. Novotny, M. Fruscione, J. Sloan, D. Schrag (2016)
Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 34 6
Manesh Patel, John Calhoon, G. Dehmer, James Grantham, Thomas Maddox, David Maron, Peter Smith (2017)
ACC/AATS/AHA/ASE/ASNC/SCAI/SCCT/STS 2017 Appropriate Use Criteria for Coronary Revascularization in Patients With Stable Ischemic Heart Disease: A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association,Journal of the American College of Cardiology, 69 17
J. Spertus (2008)
Evolving Applications for Patient-Centered Health Status MeasuresCirculation, 118
J. Spertus, T. Dewhurst, C. Dougherty, P. Nichol (2001)
Testing the effectiveness of converting patients to long-acting antianginal medications: The Quality of Life in Angina Research Trial (QUART).American heart journal, 141 4
Malik (2020)
1540JAMA Intern Med, 180
Stone (2006)
566J Am Coll Cardiol, 48
Patel (2018)
117Am Heart J, 201
Joseph Kim, R. Henderson, S. Pocock, T. Clayton, M. Sculpher, K. Fox (2005)
Health-related quality of life after interventional or conservative strategy in patients with unstable angina or non-ST-segment elevation myocardial infarction: one-year results of the third Randomized Intervention Trial of unstable Angina (RITA-3).Journal of the American College of Cardiology, 45 2
Goldman (1981)
1227Circulation, 64
J. Spertus, E. Peterson, J. Rumsfeld, Philip Jones, C. Decker, H. Krumholz (2006)
The Prospective Registry Evaluating Myocardial Infarction: Events and Recovery (PREMIER)--evaluating the impact of myocardial infarction on patient outcomes.American heart journal, 151 3
J. Spertus, E. Peterson, M. Conard, P. Heidenreich, H. Krumholz, Philip Jones, P. McCullough, Ileana Pina, Joseph Tooley, W. Weintraub, J. Rumsfeld (2005)
Monitoring clinical changes in patients with heart failure: a comparison of methods.American heart journal, 150 4
A. Shafiq, S. Arnold, Kensey Gosch, Faraz Kureshi, T. Breeding, Philip Jones, J. Beltrame, J. Spertus (2016)
Patient and physician discordance in reporting symptoms of angina among stable coronary artery disease patients: Insights from the Angina Prevalence and Provider Evaluation of Angina Relief (APPEAR) study.American heart journal, 175
Al-Lamee (2018)
31Lancet, 391
Rinfret (2001)
1614J Am Coll Cardiol, 38
Nassif (2017)
Precision medicine for cardiac resynchronization: predicting quality of life benefits for individual patients?an analysis from 5 clinical trials.Circ Heart Fail, 10
M. Nassif, Yuanyuan Tang, John Cleland, William Abraham, C. Linde, Michael Gold, James Young, J. Daubert, L. Sherfesee, D. Schaber, Anthony Tang, Philip Jones, S. Arnold, J. Spertus (2017)
Precision Medicine for Cardiac Resynchronization: Predicting Quality of Life Benefits for Individual Patients—An Analysis From 5 Clinical TrialsCirculation: Heart Failure, 10
Antianginal Efficacy of Ranolazine When Added to Treatment with Amlodipine the Erica (efficacy of Ranolazine in Chronic Angina) Trial
Abdallah (2013)
1581JAMA, 310
P. Chan, Philip Jones, Suzanne Arnold, J. Spertus (2014)
Development and Validation of a Short Version of the Seattle Angina QuestionnaireCirculation: Cardiovascular Quality and Outcomes, 7
Spertus (2001)
369Jt Comm J Qual Improv, 27
R. Al-Lamee, J. Howard, M. Shun-shin, David Thompson, H. Dehbi, S. Sen, S. Nijjer, R. Petraco, J. Davies, Thomas Keeble, K. Tang, I. Malik, Christopher Cook, Y. Ahmad, Andrew Sharp, R. Gerber, C. Baker, R. Kaprielian, S. Talwar, R. Assomull, Graham Cole, N. Keenan, G. Kanaganayagam, J. Sehmi, R. Wensel, F. Harrell, J. Mayet, S. Thom, J. Davies, D. Francis (2018)
Fractional Flow Reserve and Instantaneous Wave-Free Ratio as Predictors of the Placebo-Controlled Response to Percutaneous Coronary Intervention in Stable Single-Vessel Coronary Artery Disease: Physiology-Stratified Analysis of ORBITACirculation, 138
Kim (2005)
221J Am Coll Cardiol, 45
D. Pauly, B. Johnson, R. Anderson, E. Handberg, K. Smith, R. Cooper-DeHoff, G. Sopko, Barry Sharaf, S. Kelsey, C. Merz, C. Pepine (2011)
In women with symptoms of cardiac ischemia, nonobstructive coronary arteries, and microvascular dysfunction, angiotensin-converting enzyme inhibition is associated with improved microvascular function: A double-blind randomized study from the National Heart, Lung and Blood Institute Women's IschemiaAmerican heart journal, 162 4
Spertus (2006)
589Am Heart J, 151
ImportancePatient-reported outcomes are increasingly used as end points in clinical trials, assessments in clinical care, and tools for population health, with an increasing role in quality assessment. For patients with coronary artery disease, the Seattle Angina Questionnaire (SAQ) has emerged as the most commonly used measure of disease-specific health status to quantify patients’ symptoms of angina and the extent to which their angina affects their functioning and quality of life. This review explains how to interpret the SAQ and describes the construction and face validity of the SAQ, focusing on aligning scores and changes in scores with clinical constructs. ObservationsThe SAQ asks questions similar to those an experienced clinician would ask of a patient with stable ischemic heart disease. Therefore, SAQ scores can be aligned with clinical constructs (eg, scores on the SAQ angina frequency scale of 0-30 points indicate daily angina, 31-60 points indicate weekly angina, 61-99 points indicate monthly angina, and 100 points indicate no angina), and changes in scores can be described by aligning them with changes in question responses. After clinical thresholds are defined, it is important for clinical trials to not simply report mean differences between treatment arms but to also report the distributions of patients who have had clinically important benefits so that a number needed to treat can be generated. Conclusions and RelevanceThe widespread use of the SAQ is a consequence of its well-established validity, reproducibility, prognostic importance, and sensitivity to clinical change. Nevertheless, interpreting the SAQ can be challenging because of lack of familiarity with the clinical importance of its domains, either cross-sectionally or longitudinally. This review provides an overview of the interpretability of the SAQ as a foundation for its use as an end point in clinical trials, a tool to support more patient-centered care, and a means of facilitating population health strategies to provide a better foundation for the integration of patient experiences with clinical care.
JAMA Cardiology – American Medical Association
Published: May 10, 2021
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.