Access the full text.
Sign up today, get DeepDyve free for 14 days.
A. Robinson, C. Trankle, G. Eubanks, C. Schumann, P. Thompson, Ryan Wallace, S. Gottiparthi, Benjamin Ruth, C. Kramer, M. Salerno, K. Bilchick, C. Deen, M. Kontos, J. Dent (2020)
Off-label Use of Direct Oral Anticoagulants Compared With Warfarin for Left Ventricular Thrombi.JAMA cardiology
Letters common, persistent opioid use after cardiac surgery is sig- To DOAC or Not to DOAC for Left Ventricular nificantly lower. In Canada, new persistent opioid use after Thrombi—What Is the Dose? cardiac surgery is only approximately 3% compared with To the Editor The observational study published by Robinson nearly 10% in the US. and colleagues (Retrospective Evaluation of DOACs and Vas- It has become abundantly clear that safe persistent opi- cular Endpoints of Left Ventricular Thrombi [RED VELVT] oid use can only occur as part of a comprehensive chronic pain study) provides important new data to an area that lacks a ro- management plan, and the involvement of pain specialists is bust base of evidence. Direct oral anticoagulants (DOACs) have imperative to reduce the risk of inappropriate chronic opioid become preferred pharmacotherapy options for adults with use. It is our recommendation that when a patient requests ad- nonvalvular atrial fibrillation, given the noninferiority to war- ditional opioids for postoperative pain more than 30 days af- farin for stroke prevention and superior safety profile with less ter surgery, that patient should be referred to a pain special- major bleeding. Although vitamin K antagonists (eg, warfa- ist. While the enhanced
JAMA Cardiology – American Medical Association
Published: May 20, 2021
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.