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N. Sepehrvand, W. Alemayehu, D. Das, A. Gupta, P. Gouda, A. Ghimire, A. Du, S. Hatami, H. Babadagli, Sanam Verma, Z. Kashour, J. Ezekowitz (2019)
Trends in the Explanatory or Pragmatic Nature of Cardiovascular Clinical Trials Over 2 Decades.JAMA cardiology
Ravi Patel, M. Vaduganathan, Ayman Samman-Tahhan, A. Kalogeropoulos, V. Georgiopoulou, G. Fonarow, M. Gheorghiade, J. Butler (2016)
Trends in Utilization of Surrogate Endpoints in Contemporary Cardiovascular Clinical Trials.The American journal of cardiology, 117 11
Letters Published Online: February 5, 2020. doi:10.1001/jamacardio.2019.5807 convolution kernel (B26f). When motion artifact was present, itwasdistinguishedbyvisualanalysisofanexperiencedobserver Conflict of Interest Disclosures: None reported. and colorized pixels related to motion were excluded. Additional Contributions: We thank Werner Klotz (Department of Internal Medicine II, Medical University Innsbruck, Innsbruck, Austria) and Markus Although we agree that cardiac motion, beam hardening, Erhardt (Department of Radiology, Medical University Innsbruck) for their and partial volume effects may produce substantial artifact, contribution to drafting this letter. No compensation was received for these these issues were not significant limitations in our study. Ar- contributions. tifacts related to motion would be expected to produce blurred 1. Klauser AS, Halpern EJ, Strobl S, et al. Dual-energy computed tomography areas of colorization corresponding to areas of maximum detection of cardiovascular monosodium urate deposits in patients with gout. JAMA Cardiol. 2019;4(10):1019-1028. doi:10.1001/jamacardio.2019.3201 motion, such as the mid–right coronary artery, not the well- 2. Chhana A, Doyle A, Sevao A, et al. Advanced imaging assessment of gout: defined color-coded regions corresponding to vascular plaques comparison of dual-energy CT and MRI with anatomical pathology. Ann Rheum that we observed. Dual-energy findings related to beam hard- Dis. 2018;77(4):629-630. doi:10.1136/annrheumdis-2017-211343 ening might be expected to streak
JAMA Cardiology – American Medical Association
Published: Apr 19, 2020
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