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Randomized Trial Needed to Confirm Whether Dalcetrapib Improves Outcomes for Specific ADCY9 Genotype—Reply

Randomized Trial Needed to Confirm Whether Dalcetrapib Improves Outcomes for Specific ADCY9... Letters 4. JensenMD,RyanDH,ApovianCM,etal;AmericanCollegeofCardiology/American cardiovascular outcomes in patients with a recent acute HeartAssociationTaskForceonPracticeGuidelines;ObesitySociety.2013AHA/ACC/ coronary syndrome and AA genotype at the rs1967309 SNP TOS guideline for the management of overweight and obesity in adults: a report of in the ADCY9 gene. the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. J Am Coll Cardiol. 2014;63(25, pt B): 2985-3023. doi:10.1016/j.jacc.2013.11.004 Marc A. Pfeffer, MD, PhD Marie-Pierre Dubé, PhD Randomized Clinical Trial Needed to Confirm Jean-Claude Tardif, MD Whether Dalcetrapib Improves Outcomes Author Affiliations: Cardiovascular Division, Brigham and Women’s Hospital, for Specific ADCY9 Genotype Boston, Massachusetts (Pfeffer); Montreal Heart Institute, Université de To the Editor Nissen et al conducted a nested case-control study Montréal Beaulieu-Saucier, Montreal, Quebec, Canada (Dubé); Montreal Heart from a subgroup of the Assessment of Clinical Effects of Cho- Institute Coordinating Center, Universite de Montréal, Montreal, Quebec, Canada (Tardif). lesteryl Ester Transfer Protein Inhibition with Evacetrapib in Corresponding Author: Marc A. Pfeffer, MD, PhD, Cardiovascular Division, Patients at a High Risk for Vascular Outcomes (ACCELERATE) Brigham and Women’s Hospital, 75 Francis St, Boston, MA 02115 trial “to determine whether the association between the SNP (mpfeffer@rics.bwh.harvard.edu). [single-nucleotide polymorphism] in the ADCY9 gene and a http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Cardiology American Medical Association

Randomized Trial Needed to Confirm Whether Dalcetrapib Improves Outcomes for Specific ADCY9 Genotype—Reply

JAMA Cardiology , Volume 3 (9) – Sep 8, 2018

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References (6)

Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
2380-6583
eISSN
2380-6591
DOI
10.1001/jamacardio.2018.2382
Publisher site
See Article on Publisher Site

Abstract

Letters 4. JensenMD,RyanDH,ApovianCM,etal;AmericanCollegeofCardiology/American cardiovascular outcomes in patients with a recent acute HeartAssociationTaskForceonPracticeGuidelines;ObesitySociety.2013AHA/ACC/ coronary syndrome and AA genotype at the rs1967309 SNP TOS guideline for the management of overweight and obesity in adults: a report of in the ADCY9 gene. the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. J Am Coll Cardiol. 2014;63(25, pt B): 2985-3023. doi:10.1016/j.jacc.2013.11.004 Marc A. Pfeffer, MD, PhD Marie-Pierre Dubé, PhD Randomized Clinical Trial Needed to Confirm Jean-Claude Tardif, MD Whether Dalcetrapib Improves Outcomes Author Affiliations: Cardiovascular Division, Brigham and Women’s Hospital, for Specific ADCY9 Genotype Boston, Massachusetts (Pfeffer); Montreal Heart Institute, Université de To the Editor Nissen et al conducted a nested case-control study Montréal Beaulieu-Saucier, Montreal, Quebec, Canada (Dubé); Montreal Heart from a subgroup of the Assessment of Clinical Effects of Cho- Institute Coordinating Center, Universite de Montréal, Montreal, Quebec, Canada (Tardif). lesteryl Ester Transfer Protein Inhibition with Evacetrapib in Corresponding Author: Marc A. Pfeffer, MD, PhD, Cardiovascular Division, Patients at a High Risk for Vascular Outcomes (ACCELERATE) Brigham and Women’s Hospital, 75 Francis St, Boston, MA 02115 trial “to determine whether the association between the SNP (mpfeffer@rics.bwh.harvard.edu). [single-nucleotide polymorphism] in the ADCY9 gene and a

Journal

JAMA CardiologyAmerican Medical Association

Published: Sep 8, 2018

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