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Prioritizing Dissemination and Implementation Science in Cardiometabolic Medicine

Prioritizing Dissemination and Implementation Science in Cardiometabolic Medicine Opinion EDITORIAL Prioritizing Dissemination and Implementation Science in Cardiometabolic Medicine CONNECTing the Dots Ankeet S. Bhatt, MD, MBA; Scott D. Solomon, MD; Muthiah Vaduganathan, MD, MPH charge plans that included rationale for prescribed medica- Heart failure with reduced ejection fraction serves as a pro- totypical example in which advances in scientific discovery tions and contingency plans. have not been fully realized in clinical practice. In recent years, The in-hospital and postdischarge intervention did not stepwise progress in discovery science has afforded the avail- result in improvement in clinical outcomes or measures of ability of several disease- quality of care, based on the coprimary outcomes of time to modifying therapies. Com- first heart failure rehospitalization or death or change in a Related article page 314 plete uptake of contemporary composite heart failure quality-of-care score (based on per- multidrug regimens is estimated to provide significant im- centage of recommendations followed). Specifically, heart provements in longevity and event-free survival. However, failure rehospitalization or all-cause mortality occurred in deep, pervasive gaps have remained in the optimal adoption 38.6% in the intervention group vs 39.2% in the usual care of these therapies. Similar implementation gaps exist group (adjusted hazard ratio, 0.92 [95% CI, 0.81 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Prioritizing Dissemination and Implementation Science in Cardiometabolic Medicine

JAMA , Volume 326 (4) – Jul 27, 2021

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References (11)

Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2021.9847
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Prioritizing Dissemination and Implementation Science in Cardiometabolic Medicine CONNECTing the Dots Ankeet S. Bhatt, MD, MBA; Scott D. Solomon, MD; Muthiah Vaduganathan, MD, MPH charge plans that included rationale for prescribed medica- Heart failure with reduced ejection fraction serves as a pro- totypical example in which advances in scientific discovery tions and contingency plans. have not been fully realized in clinical practice. In recent years, The in-hospital and postdischarge intervention did not stepwise progress in discovery science has afforded the avail- result in improvement in clinical outcomes or measures of ability of several disease- quality of care, based on the coprimary outcomes of time to modifying therapies. Com- first heart failure rehospitalization or death or change in a Related article page 314 plete uptake of contemporary composite heart failure quality-of-care score (based on per- multidrug regimens is estimated to provide significant im- centage of recommendations followed). Specifically, heart provements in longevity and event-free survival. However, failure rehospitalization or all-cause mortality occurred in deep, pervasive gaps have remained in the optimal adoption 38.6% in the intervention group vs 39.2% in the usual care of these therapies. Similar implementation gaps exist group (adjusted hazard ratio, 0.92 [95% CI, 0.81

Journal

JAMAAmerican Medical Association

Published: Jul 27, 2021

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