Poloxamer 188 for Sickle Cell Disease
Abstract
Research Editor's Note Poloxamer 188 for Sickle Cell Disease Editor's Note Jody Zylke, MD Although effective treatments exist to prevent painful The trial by Casella et al was completed in 2016, 5 years vaso-occlusive episodes in patients with sickle cell dis- ago, and is much older than the randomized clinical trials that ease (ie, hydroxyurea), finding therapies to reduce the se- JAMA usually publishes. Why did the editors decide to ac- verity or duration of episodes once they...