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References (27)
-
P. Autier, M. Boniol, C. Pizot, P. Mullie (2014)
Vitamin D status and ill health: a systematic review.The lancet. Diabetes & endocrinology, 2 1
-
Liu (2006)
1770Science, 311
-
E. Etten, C. Mathieu (2005)
Immunoregulation by 1,25-dihydroxyvitamin D3: Basic conceptsThe Journal of Steroid Biochemistry and Molecular Biology, 97
-
Gaëlle Annweiler, M. Corvaisier, J. Gautier, V. Dubée, E. Legrand, G. Sacco, C. Annweiler (2020)
Vitamin D Supplementation Associated to Better Survival in Hospitalized Frail Elderly COVID-19 Patients: The GERIA-COVID Quasi-Experimental StudyNutrients, 12
-
J. Pieters (2006)
Faculty Opinions recommendation of Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. -
M. Aglipay, C. Birken, P. Parkin, M. Loeb, K. Thorpe, Yang Chen, A. Laupacis, M. Mamdani, C. Macarthur, J. Hoch, T. Mazzulli, J. Maguire (2017)
Effect of High-Dose vs Standard-Dose Wintertime Vitamin D Supplementation on Viral Upper Respiratory Tract Infections in Young Healthy ChildrenJAMA, 318
-
P. Bacchetti, C. McCulloch, M. Segal (2008)
Simple, Defensible Sample Sizes Based on Cost EfficiencyBiometrics, 64
-
PT Liu, S Stenger, H Li (2006)
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response, 311
-
A. Franco, T. Freitas, W. Bernardo, R. Pereira (2017)
Vitamin D supplementation and disease activity in patients with immune-mediated rheumatic diseasesMedicine, 96
-
P. Bacchetti (2010)
Current sample size conventions: Flaws, harms, and alternativesBMC Medicine, 8
-
M. Kearns, J. Alvarez, V. Tangpricha (2014)
Large, single-dose, oral vitamin D supplementation in adult populations: a systematic review.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 20 4
-
P. Ilie, S. Stefanescu, Lee Smith (2020)
The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortalityAging Clinical and Experimental Research, 32
-
Research Original Investigation Effect of a Single High Dose of Vitamin D 3 in Patients With Moderate to Severe -
G. Carpagnano, V. Lecce, V. Quaranta, A. Zito, E. Buonamico, E. Capozza, A. Palumbo, G. Gioia, V. Valerio, O. Resta (2020)
Vitamin D deficiency as a predictor of poor prognosis in patients with acute respiratory failure due to COVID-19Journal of Endocrinological Investigation, 44
-
A. Martineau, David Jolliffe, R. Hooper, L. Greenberg, J. Aloia, P. Bergman, G. Dubnov-Raz, S. Esposito, D. Ganmaa, A. Ginde, E. Goodall, C. Grant, C. Griffiths, W. Janssens, I. Laaksi, S. Manaseki-Holland, D. Mauger, D. Murdoch, R. Neale, J. Rees, S. Simpson, I. Stelmach, G. Kumar, M. Urashima, C. Camargo (2017)
Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant dataThe BMJ, 356
-
J. Hernández, D. Nan, M. Fernández-Ayala, M. Garcia-Unzueta, M. Hernández-Hernández, M. López-Hoyos, P. Muñoz-Cacho, J. Olmos, M. Gutiérrez-Cuadra, J. Ruiz-Cubillan, J. Crespo, V. Martínez-Taboada (2020)
Vitamin D Status in Hospitalized Patients with SARS-CoV-2 InfectionThe Journal of Clinical Endocrinology and Metabolism
-
G. Campbell, S. Spector (2012)
Autophagy induction by vitamin D inhibits both Mycobacterium tuberculosis and human immunodeficiency virus type 1Autophagy, 8
-
M. Laplana, J. Royo, J. Fibla (2018)
Vitamin D Receptor polymorphisms and risk of enveloped virus infection: A meta-analysis.Gene, 678
-
A. Martineau, N. Forouhi (2020)
Vitamin D for COVID-19: a case to answer?The Lancet. Diabetes & Endocrinology, 8
-
J. Cannell, R. Vieth, J. Umhau, M. Holick, W. Grant, S. Madronich, C. Garland, E. Giovannucci (2006)
Epidemic influenza and vitamin DEpidemiology and Infection, 134
-
H. Kaufman, J. Niles, M. Kroll, Caixia Bi, M. Holick (2020)
SARS-CoV-2 positivity rates associated with circulating 25-hydroxyvitamin D levelsPLoS ONE, 15
-
Fiona Mitchell (2020)
Vitamin-D and COVID-19: do deficient risk a poorer outcome?The Lancet. Diabetes & Endocrinology, 8
-
(2020)
Mechanisms in endocrinology: vitamin D and COVID-19. -
J. Sabetta, P. DePetrillo, R. Cipriani, J. Smardin, Lillian Burns, M. Landry (2010)
Serum 25-Hydroxyvitamin D and the Incidence of Acute Viral Respiratory Tract Infections in Healthy AdultsPLoS ONE, 5
-
D. Meltzer, Thomas Best, Hui Zhang, T. Vokes, V. Arora, J. Solway (2020)
Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test ResultsJAMA Network Open, 3
-
O. Aibana, Chuan-Chin Huang, S. Aboud, A. Arnedo-Pena, M. Becerra, J. Bellido-Blasco, R. Bhosale, R. Calderón, S. Chiang, C. Contreras, G. Davaasambuu, W. Fawzi, M. Franke, J. Galea, D. Garcia-Ferrer, M. Gil-Fortuño, B. Gomila-Sard, Amita Gupta, N. Gupte, R. Hussain, J. Iborra-Millet, N. Iqbal, J. Juan-Cerdán, A. Kinikar, L. Lecca, V. Mave, N. Meseguer-Ferrer, G. Montepiedra, F. Mugusi, O. Owolabi, J. Parsonnet, Freddy Roach-Poblete, M. Romeu-García, S. Spector, C. Sudfeld, M. Tenforde, T. Togun, R. Yataco, Zibiao Zhang, M. Murray (2019)
Vitamin D status and risk of incident tuberculosis disease: A nested case-control study, systematic review, and individual-participant data meta-analysisPLoS Medicine, 16
-
Bilezikian (2020)
R133Eur J Endocrinol, 183
- Publisher
- American Medical Association
- Copyright
- Copyright 2021 American Medical Association. All Rights Reserved.
- ISSN
- 0098-7484
- eISSN
- 1538-3598
- DOI
- 10.1001/jama.2020.26848
- Publisher site
- See Article on Publisher Site
Abstract
Key PointsQuestionWhat is the effect of a single high dose of vitamin D3 on hospital length of stay among hospitalized patients with moderate to severe coronavirus disease 2019 (COVID-19)? FindingsIn this randomized clinical trial that involved 240 hospitalized patients with moderate to severe COVID-19, a single dose of 200 000 IU of vitamin D3, compared with placebo, did not significantly reduce hospital length of stay (median of 7.0 vs 7.0 days; unadjusted hazard ratio for hospital discharge, 1.07). MeaningThe study does not support the use of a high dose of vitamin D3 for treatment of moderate to severe COVID-19 in hospitalized patients.
Journal
JAMA – American Medical Association
Published: Mar 16, 2021