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Association of Screening and Treatment With Breast Cancer Mortality by Molecular Subtype in US Women, 2000-2012

Association of Screening and Treatment With Breast Cancer Mortality by Molecular Subtype in US... Key PointsQuestionWhat are the associations of screening and adjuvant treatment with reductions in US breast cancer mortality rates by molecular subtype? FindingsIn this study of 6 simulation models that projected US breast cancer mortality trends for women aged 30 to 79 years, advances in treatment, such as use of newer adjuvant therapies, compared with screening advances were associated with greater estimated reductions in overall breast cancer mortality from 2000 to 2012, although the associations varied by breast cancer molecular subtype. MeaningSimulation modeling estimated that advances in treatment were associated with greater decreases in breast cancer mortality rates than advances in screening, although these associations varied by molecular subtype. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

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References (36)

Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2017.19130
pmid
29318276
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionWhat are the associations of screening and adjuvant treatment with reductions in US breast cancer mortality rates by molecular subtype? FindingsIn this study of 6 simulation models that projected US breast cancer mortality trends for women aged 30 to 79 years, advances in treatment, such as use of newer adjuvant therapies, compared with screening advances were associated with greater estimated reductions in overall breast cancer mortality from 2000 to 2012, although the associations varied by breast cancer molecular subtype. MeaningSimulation modeling estimated that advances in treatment were associated with greater decreases in breast cancer mortality rates than advances in screening, although these associations varied by molecular subtype.

Journal

JAMAAmerican Medical Association

Published: Jan 9, 2018

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