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Key PointsQuestionWhat are the associations of screening and adjuvant treatment with reductions in US breast cancer mortality rates by molecular subtype? FindingsIn this study of 6 simulation models that projected US breast cancer mortality trends for women aged 30 to 79 years, advances in treatment, such as use of newer adjuvant therapies, compared with screening advances were associated with greater estimated reductions in overall breast cancer mortality from 2000 to 2012, although the associations varied by breast cancer molecular subtype. MeaningSimulation modeling estimated that advances in treatment were associated with greater decreases in breast cancer mortality rates than advances in screening, although these associations varied by molecular subtype.
JAMA – American Medical Association
Published: Jan 9, 2018
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