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Proportion of Adults With Sickle Cell Anemia and Pain Crises Receiving Hydroxyurea

Proportion of Adults With Sickle Cell Anemia and Pain Crises Receiving Hydroxyurea Letters RESEARCH LETTER Table. Characteristics of 2086 Adults With Probable Sickle Cell Anemia (SCA) Reported in a Large Commercial Insurance Database Between Proportion of Adults With Sickle Cell Anemia January 1, 2009, and June 30, 2013 and Pain Crises Receiving Hydroxyurea Adults With The recommendation from the 2014 National Heart, Lung, and Probable SCA Blood Institute guidelines to treat all adults with sickle cell Age, median (25th-75th percentile), y 39 (28-52) anemia (SCA) and 3 or more moderate to severe pain crises Female sex 1231 (59.0) [56.9-61.1] within 1 year with hydroxyurea was rated as strong based on 2,3 Duration of continuous enrollment, 30.0 (13.9-52.9) high-quality evidence reviewed in 2008. Despite benefits in median (25th-75th percentile), mo reducing pain crises, hospitalizations, blood transfusions, and Filled ≥1 prescription for hydroxyurea 369 (17.7) possibly mortality, it is thought that hydroxyurea is under- during enrollment period [16.1-19.4] used, although the extent of its use is unknown. We sought Average number of emergency visits 0.70 (0-2.10) or hospitalizations for pain per year, to document the use of hydroxyurea when indicated for SCA median (25th-75th percentile) in a large insurance claims database. Emergency visit or hospitalization for pain during enrollment period ≥1 1420 (68.1) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Proportion of Adults With Sickle Cell Anemia and Pain Crises Receiving Hydroxyurea

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References (8)

Publisher
American Medical Association
Copyright
Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2015.3075
pmid
25919532
Publisher site
See Article on Publisher Site

Abstract

Letters RESEARCH LETTER Table. Characteristics of 2086 Adults With Probable Sickle Cell Anemia (SCA) Reported in a Large Commercial Insurance Database Between Proportion of Adults With Sickle Cell Anemia January 1, 2009, and June 30, 2013 and Pain Crises Receiving Hydroxyurea Adults With The recommendation from the 2014 National Heart, Lung, and Probable SCA Blood Institute guidelines to treat all adults with sickle cell Age, median (25th-75th percentile), y 39 (28-52) anemia (SCA) and 3 or more moderate to severe pain crises Female sex 1231 (59.0) [56.9-61.1] within 1 year with hydroxyurea was rated as strong based on 2,3 Duration of continuous enrollment, 30.0 (13.9-52.9) high-quality evidence reviewed in 2008. Despite benefits in median (25th-75th percentile), mo reducing pain crises, hospitalizations, blood transfusions, and Filled ≥1 prescription for hydroxyurea 369 (17.7) possibly mortality, it is thought that hydroxyurea is under- during enrollment period [16.1-19.4] used, although the extent of its use is unknown. We sought Average number of emergency visits 0.70 (0-2.10) or hospitalizations for pain per year, to document the use of hydroxyurea when indicated for SCA median (25th-75th percentile) in a large insurance claims database. Emergency visit or hospitalization for pain during enrollment period ≥1 1420 (68.1)

Journal

JAMA – American Medical Association

Published: Apr 28, 2015

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