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COMMENTARY ONLINE FIRST Mandatory HPV Vaccination and Political Debate to 24 years (44.8% for ages 20-24 years), followed by a Lawrence O. Gostin, JD gradual decline through age 59 years; high-risk HPV types are detected in only 3.4% of women tested. ACCINATIONS ARE AMONG THE MOST COST- Nononcogenic HPV types 6 and 11 are associated with effective and widely used public health interven- genital warts and recurrent respiratory papillomatosis. High- tions but have provoked popular resistance, with risk HPV types are detected in virtually all cervical, vagi- Vcompulsory vaccination framed as an unwarranted nal, and vulvar cancers in women, and HPV types 16 and state interference. When the US Food and Drug Administra- 18 are associated with 70% of cervical cancers. Each year, tion (FDA) approved a human papillomavirus (HPV) vac- more than 12 000 new cervical cancer cases are diagnosed cine in 2006, conservative religious groups strongly opposed in the United States, with more than 4000 deaths from cer- a mandate, arguing it would condone premarital sex and un- vical cancer occurring annually. Human papillomavirus also dermine parental rights. Yet Governor Rick Perry signed an is associated with cancer of the penis, as well as cancers of executive
JAMA – American Medical Association
Published: Oct 19, 2011
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