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Effect of Food Additives on Hyperphosphatemia Among Patients With End-stage Renal Disease

Effect of Food Additives on Hyperphosphatemia Among Patients With End-stage Renal Disease ORIGINAL CONTRIBUTION Effect of Food Additives on Hyperphosphatemia Among Patients With End-stage Renal Disease A Randomized Controlled Trial Catherine Sullivan, MS, RD, LD Context High dietary phosphorus intake has deleterious consequences for renal pa- Srilekha S. Sayre, MS, RD, LD tients and is possibly harmful for the general public as well. To prevent hyperphos- phatemia, patients with end-stage renal disease limit their intake of foods that are natu- Janeen B. Leon, MS, RD, LD rally high in phosphorus. However, phosphorus-containing additives are increasingly Rhoderick Machekano, MPH, PhD being added to processed and fast foods. The effect of such additives on serum phos- phorus levels is unclear. Thomas E. Love, PhD Objective To determine the effect of limiting the intake of phosphorus-containing David Porter, BA food additives on serum phosphorus levels among patients with end-stage renal Marquisha Marbury, AAS disease. Ashwini R. Sehgal, MD Design, Setting, and Participants Cluster randomized controlled trial at 14 long- term hemodialysis facilities in northeast Ohio. Two hundred seventy-nine patients with elevated baseline serum phosphorus levels (5.5 mg/dL) were recruited between May NDIVIDUALS WITH MODERATE TO and October 2007. Two shifts at each of 12 large facilities and 1 shift at each of 2 severe http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Effect of Food Additives on Hyperphosphatemia Among Patients With End-stage Renal Disease

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References (52)

Publisher
American Medical Association
Copyright
Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2009.96
pmid
19211470
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL CONTRIBUTION Effect of Food Additives on Hyperphosphatemia Among Patients With End-stage Renal Disease A Randomized Controlled Trial Catherine Sullivan, MS, RD, LD Context High dietary phosphorus intake has deleterious consequences for renal pa- Srilekha S. Sayre, MS, RD, LD tients and is possibly harmful for the general public as well. To prevent hyperphos- phatemia, patients with end-stage renal disease limit their intake of foods that are natu- Janeen B. Leon, MS, RD, LD rally high in phosphorus. However, phosphorus-containing additives are increasingly Rhoderick Machekano, MPH, PhD being added to processed and fast foods. The effect of such additives on serum phos- phorus levels is unclear. Thomas E. Love, PhD Objective To determine the effect of limiting the intake of phosphorus-containing David Porter, BA food additives on serum phosphorus levels among patients with end-stage renal Marquisha Marbury, AAS disease. Ashwini R. Sehgal, MD Design, Setting, and Participants Cluster randomized controlled trial at 14 long- term hemodialysis facilities in northeast Ohio. Two hundred seventy-nine patients with elevated baseline serum phosphorus levels (5.5 mg/dL) were recruited between May NDIVIDUALS WITH MODERATE TO and October 2007. Two shifts at each of 12 large facilities and 1 shift at each of 2 severe

Journal

JAMA – American Medical Association

Published: Feb 11, 2009

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