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SPECIAL COMMUNICATION John S. Kaddis, BS Human islet research is crucial to understanding the cellular biology of the Barbara J. Olack pancreas in developing therapeutic options for diabetes patients and in at- Janice Sowinski, MS tempting to prevent the development of this disease. The national Islet Cell James Cravens, MPH Resource Center Consortium provides human pancreatic islets for diabetes Juan L. Contreras, MD research while simultaneously addressing the need to improve islet isola- Joyce C. Niland, PhD tion and transplantation technologies. Since its inception in 2001, the con- sortium has supplied 297.6 million islet equivalents to 151 national and in- HE GOAL OF THIS ARTICLE IS TO ternational scientists for use in clinical and laboratory projects. Data on the highlight the use of human volume, quality, and frequency of shipments substantiate the importance pancreatic islets as a critical re- Tsource for investigators study- of human islets for diabetes research, as do the number of funded grants for ing diabetes mellitus. The national beta-cell projects and publications produced as a direct result of islets sup- Islet Cell Resource (ICR) Center Con- plied by this resource. Limitations in using human islets are discussed, along sortium is the first and largest orga-
JAMA – American Medical Association
Published: Apr 15, 2009
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