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SPECIAL COMMUNICATION CLINICIAN’S CORNER Rethinking Screening for Breast Cancer and Prostate Cancer Laura Esserman, MD, MBA After 20 years of screening for breast and prostate cancer, several observa- Yiwey Shieh, AB tions can be made. First, the incidence of these cancers increased after Ian Thompson, MD the introduction of screening but has never returned to prescreening levels. REAST CANCER AND PROSTATE Second, the increase in the relative fraction of early stage cancers has in- cancer account for 26% of all creased. Third, the incidence of regional cancers has not decreased at a com- cancers in the United States, mensurate rate. One possible explanation is that screening may be increas- Bwith an estimated 386 560 pa- ing the burden of low-risk cancers without significantly reducing the burden tients diagnosed annually: 194 280 for of more aggressively growing cancers and therefore not resulting in the an- breast cancer and 192 280 for prostate ticipated reduction in cancer mortality. To reduce morbidity and mortality cancer For both, there are remarkable differences between outcomes of local- from prostate cancer and breast cancer, new approaches for screening, early ized vs advanced disease (breast can- detection, and prevention for both diseases should be considered. cer:
JAMA – American Medical Association
Published: Oct 21, 2009
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