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Evolving From Reductionism to Holism

Evolving From Reductionism to Holism COMMENTARY MEDICINE AND LAW Is There a Future for Systems Medicine? tal factors—and how these components contribute to the Howard J. Federoff, MD, PhD course of health and disease. Stemming from systems biol- Lawrence O. Gostin, JD ogy, systems medicine incorporates interactions between all components of health and disease. Care for the whole per- EALTH REFORM DISCUSSIONS REVOLVE AROUND HOW son—derived from the medical tenets of cura personalis— best to achieve the goals of cost containment, in- exemplifies the connectivity and integration at multiple lev- creased access to care, and improved quality. How- els of systems medicine, expanding medicine beyond Hever, in the current health reform debate, little reductionism. Positing this holistic approach requires not attention is paid to how medicine is currently taught and only new organizing principles but also retention of medi- practiced. It has long been understood that the fundamen- cine’s rigorous scientific foundation. tal tenets of health arise from understanding the interac- Why Transition Toward Systems Medicine tion among genomics, the external environment, and be- havior. Modern medicine often neglects this comprehensive A key feature of systems medicine is that existing net- model and treats disease in isolation, without taking into works, through dynamic (time-dependent) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Evolving From Reductionism to Holism

JAMA , Volume 302 (9) – Sep 2, 2009

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References (11)

Publisher
American Medical Association
Copyright
Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2009.1264
pmid
19724047
Publisher site
See Article on Publisher Site

Abstract

COMMENTARY MEDICINE AND LAW Is There a Future for Systems Medicine? tal factors—and how these components contribute to the Howard J. Federoff, MD, PhD course of health and disease. Stemming from systems biol- Lawrence O. Gostin, JD ogy, systems medicine incorporates interactions between all components of health and disease. Care for the whole per- EALTH REFORM DISCUSSIONS REVOLVE AROUND HOW son—derived from the medical tenets of cura personalis— best to achieve the goals of cost containment, in- exemplifies the connectivity and integration at multiple lev- creased access to care, and improved quality. How- els of systems medicine, expanding medicine beyond Hever, in the current health reform debate, little reductionism. Positing this holistic approach requires not attention is paid to how medicine is currently taught and only new organizing principles but also retention of medi- practiced. It has long been understood that the fundamen- cine’s rigorous scientific foundation. tal tenets of health arise from understanding the interac- Why Transition Toward Systems Medicine tion among genomics, the external environment, and be- havior. Modern medicine often neglects this comprehensive A key feature of systems medicine is that existing net- model and treats disease in isolation, without taking into works, through dynamic (time-dependent)

Journal

JAMAAmerican Medical Association

Published: Sep 2, 2009

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