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COMMENTARY MEDICINE AND LAW Is There a Future for Systems Medicine? tal factors—and how these components contribute to the Howard J. Federoff, MD, PhD course of health and disease. Stemming from systems biol- Lawrence O. Gostin, JD ogy, systems medicine incorporates interactions between all components of health and disease. Care for the whole per- EALTH REFORM DISCUSSIONS REVOLVE AROUND HOW son—derived from the medical tenets of cura personalis— best to achieve the goals of cost containment, in- exemplifies the connectivity and integration at multiple lev- creased access to care, and improved quality. How- els of systems medicine, expanding medicine beyond Hever, in the current health reform debate, little reductionism. Positing this holistic approach requires not attention is paid to how medicine is currently taught and only new organizing principles but also retention of medi- practiced. It has long been understood that the fundamen- cine’s rigorous scientific foundation. tal tenets of health arise from understanding the interac- Why Transition Toward Systems Medicine tion among genomics, the external environment, and be- havior. Modern medicine often neglects this comprehensive A key feature of systems medicine is that existing net- model and treats disease in isolation, without taking into works, through dynamic (time-dependent)
JAMA – American Medical Association
Published: Sep 2, 2009
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