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Efficacy of Influenza Vaccine in Nursing Homes

Efficacy of Influenza Vaccine in Nursing Homes From December 10, 1982, to March 4, 1983, when influenza A (H3N2) viruses circulated in Michigan, outbreaks of influenza-like illness were identified in seven nursing homes in Genesee County; 272 (27%) of 1,018 residents were affected. Unvaccinated residents were more likely than vaccinated residents to become ill (risk ratio [RR], 2.6; 95% confidence interval [CI], 1.8-3.6) and were subsequently more likely to be hospitalized (RR, 2.4; 95% CI, 1.2-4.8), develop roentgenographically proven pneumonia (RR, 2.9; 95% CI, 1.6-5.3), or die (RR, 5.6; 95% CI, 1.2-9.1). Similar observations were made during investigations in six of the eight remaining nursing homes in Genesee County, in which 57 (12%) of 458 residents became ill sporadically. These findings suggest that influenza vaccine can reduce the incidence and severity of influenza virus infections among the elderly and chronically ill and underscore the importance of vaccination programs for those in nursing homes and in the general community. (JAMA 1985;253:1136-1139) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

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References (12)

Publisher
American Medical Association
Copyright
Copyright © 1985 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1985.03350320060017
Publisher site
See Article on Publisher Site

Abstract

From December 10, 1982, to March 4, 1983, when influenza A (H3N2) viruses circulated in Michigan, outbreaks of influenza-like illness were identified in seven nursing homes in Genesee County; 272 (27%) of 1,018 residents were affected. Unvaccinated residents were more likely than vaccinated residents to become ill (risk ratio [RR], 2.6; 95% confidence interval [CI], 1.8-3.6) and were subsequently more likely to be hospitalized (RR, 2.4; 95% CI, 1.2-4.8), develop roentgenographically proven pneumonia (RR, 2.9; 95% CI, 1.6-5.3), or die (RR, 5.6; 95% CI, 1.2-9.1). Similar observations were made during investigations in six of the eight remaining nursing homes in Genesee County, in which 57 (12%) of 458 residents became ill sporadically. These findings suggest that influenza vaccine can reduce the incidence and severity of influenza virus infections among the elderly and chronically ill and underscore the importance of vaccination programs for those in nursing homes and in the general community. (JAMA 1985;253:1136-1139)

Journal

JAMAAmerican Medical Association

Published: Feb 22, 1985

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