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Chloroquine Suppresses Skin Cancers —For a While

Chloroquine Suppresses Skin Cancers —For a While Chloroquine is giving researchers a scientific headache. On the one hand, the antimalarial drug appears to have a suppressive effect on skin cancers, while on the other hand, prolonged use may produce serious side effects, such as eye damage. This was the conclusion of three dermatologists from Baylor University (Houston), in a paper read at the XII International Congress of Dermatology at Washington last month. "Although the results obtained in this study strongly suggest that chloroquine has a suppressive effect on carcinogenesis, the absence of statistical significance at some sites indicates that reservations are in order," concluded Dr. John M. Knox, who presented the paper for his colleagues, Drs. Robert G. Freeman and Charles L. Heaton. "The findings from this study are not of sufficient magnitude to justify the routine prolonged use of a drug that may produce serious side effects, such as irreversible degenerative changes in the eyes." So http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Chloroquine Suppresses Skin Cancers —For a While

JAMA , Volume 182 (1) – Oct 6, 1962
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Chloroquine Suppresses Skin Cancers —For a While

Abstract


Chloroquine is giving researchers a scientific headache. On the one hand, the antimalarial drug appears to have a suppressive effect on skin cancers, while on the other hand, prolonged use may produce serious side effects, such as eye damage.
This was the conclusion of three dermatologists from Baylor University (Houston), in a paper read at the XII International Congress of Dermatology at Washington last month.
"Although the results obtained in this study...
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Publisher
American Medical Association
Copyright
Copyright © 1962 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1962.03050400113046
Publisher site
See Article on Publisher Site

Abstract

Chloroquine is giving researchers a scientific headache. On the one hand, the antimalarial drug appears to have a suppressive effect on skin cancers, while on the other hand, prolonged use may produce serious side effects, such as eye damage. This was the conclusion of three dermatologists from Baylor University (Houston), in a paper read at the XII International Congress of Dermatology at Washington last month. "Although the results obtained in this study strongly suggest that chloroquine has a suppressive effect on carcinogenesis, the absence of statistical significance at some sites indicates that reservations are in order," concluded Dr. John M. Knox, who presented the paper for his colleagues, Drs. Robert G. Freeman and Charles L. Heaton. "The findings from this study are not of sufficient magnitude to justify the routine prolonged use of a drug that may produce serious side effects, such as irreversible degenerative changes in the eyes." So

Journal

JAMA – American Medical Association

Published: Oct 6, 1962

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