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References (7)
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R. Illingworth (1955)
Sudden Mental Deterioration with Convulsions in InfancyArchives of Disease in Childhood, 30
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Massive Spasms in Infancy and ChildhoodEpilepsia, C4
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Infantile spasms with mental retardation. II. Treatment with cortisone and adrenocorticotropin.Pediatrics, 22 6
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Atlas of electroencephalography -
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[Electroencephalogram in looking, nodding and salaam and other types of convulsion in children].Archiv fur Psychiatrie und Nervenkrankheiten, vereinigt mit Zeitschrift fur die gesamte Neurologie und Psychiatrie, 189 1
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Henry Baird, L. Borofsky (1957)
Infantile myoclonic seizures.The Journal of pediatrics, 50 3
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E. Gibbs, M. Fleming, F. Gibbs (1954)
Diagnosis and prognosis of hypsarhythmia and infantile spasms.Pediatrics, 13 1
- Publisher
- American Medical Association
- Copyright
- Copyright © 1959 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
- ISSN
- 0098-7484
- eISSN
- 1538-3598
- DOI
- 10.1001/jama.1959.03010220032009
- Publisher site
- See Article on Publisher Site
Abstract
Hypsarhythmia is a type of epilepsy which has, in the past, had an extremely poor prognosis. Eleven per cent of the patients died before the third year of life, and 87% of those who lived were feeble-minded. The present series of 60 children were treated with corticotropin for one year, with marked improvement in 36 and almost complete relief in 5 as judged by electroencephalographic criteria and subjective symptoms. The mode of action of the drug was not explained, and its effectiveness in the individual case could not be predicted from a knowledge of the etiology. By contrast with the poor results obtained in the past, these recent results with corticotropin are encouraging.
Journal
JAMA – American Medical Association
Published: Sep 26, 1959