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The chief object of this inquiry has been to determine whether the large arteries can be occluded long enough to make it possible to observe the effect of the arrested circulation in the territory supplied by the occluded vessel, without irreparably damaging the artery during the period of observation. How long can an artery be occluded so as to arrest all flow of blood through its lumen without permanently obliterating it? What is the utmost limit of time that compression with a removable metallic band can be maintained before permanent damage, leading to thrombosis, occurs in the intima? What are the changes that occur in the vessel after occlusion has been maintained for a certain number of hours, or days, at the time of the constriction and after constriction has been removed? The importance of testing the efficiency of the collateral circulation before permanently obstructing or obliterating an important surgical
JAMA – American Medical Association
Published: Jan 28, 1911
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