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J. Myburgh, D. Cooper, S. Finfer, B. Venkatesh, Daryl Jones, A. Higgins, Nicole Bishop, Tracey Higlett (2008)
Epidemiology and 12-month outcomes from traumatic brain injury in australia and new zealand.The Journal of trauma, 64 4
C. Gross, G. Anderson, N. Powe (1999)
The relation between funding by the National Institutes of Health and the burden of disease.The New England journal of medicine, 340 24
Zhao (种), Jing-Qiong Kang, K. Maiese (2002)
Hematopoietic Factor Erythropoietin Fosters Neuroprotection through Novel Signal Transduction CascadesJournal of Cerebral Blood Flow & Metabolism, 22
K. Maiese, Zhao (种) (2004)
Insights into oxidative stress and potential novel therapeutic targets for Alzheimer disease.Restorative neurology and neuroscience, 22 2
Fiona Doetsch, I. Caillé, D. Lim, J. García-Verdugo, A. Álvarez-Buylla (1999)
Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian BrainCell, 97
H. Corwin, A. Gettinger, T. Fabian, A. May, R. Pearl, S. Heard, R. An, P. Bowers, P. Burton, M. Klausner, M. Corwin (2007)
Efficacy and safety of epoetin alfa in critically ill patients.The New England journal of medicine, 357 10
S. Juul, R. McPherson, L. Bauer, K. Ledbetter, C. Gleason, D. Mayock (2008)
A Phase I/II Trial of High-Dose Erythropoietin in Extremely Low Birth Weight Infants: Pharmacokinetics and SafetyPediatrics, 122
H. Corwin (2006)
The role of erythropoietin therapy in the critically ill.Transfusion medicine reviews, 20 1
Zhao (种), Jing-Qiong Kang, K. Maiese (2002)
Angiogenesis and plasticity: role of erythropoietin in vascular systems.Journal of hematotherapy & stem cell research, 11 6
P. Talving, T. Lustenberger, L. Kobayashi, K. Inaba, Galinos Barmparas, B. Schnüriger, L. Lam, L. Chan, D. Demetriades (2010)
Erythropoiesis Stimulating Agent Administration Improves Survival After Severe Traumatic Brain Injury: A Matched Case Control StudyAnnals of Surgery, 251
M. Brines, P. Ghezzi, Sonja Keenan, D. Agnello, N. Lanerolle, C. Cerami, L. Itri, A. Cerami (2000)
Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury.Proceedings of the National Academy of Sciences of the United States of America, 97 19
C. Bennett, S. Silver, B. Djulbegovic, A. Samaras, C. Blau, Kara Gleason, S. Barnato, Kathleen Elverman, D. Courtney, J. McKoy, B. Edwards, C. Tigue, D. Raisch, P. Yarnold, D. Dorr, T. Kuzel, M. Tallman, S. Trifilio, D. West, S. Lai, M. Henke (2008)
Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia.JAMA, 299 8
Zhao (种), Jing-Qiong Kang, K. Maiese (2003)
Apaf-1, Bcl-xL, Cytochrome c, and Caspase-9 Form the Critical Elements for Cerebral Vascular Protection by ErythropoietinJournal of Cerebral Blood Flow & Metabolism, 23
L. Napolitano, T. Fabian, K. Kelly, J. Bailey, E. Block, W. Langholff, C. Enny, H. Corwin (2008)
Improved survival of critically ill trauma patients treated with recombinant human erythropoietin.The Journal of trauma, 65 2
G. Grasso, M. Buemi, C. Alafaci, A. Sfacteria, M. Passalacqua, A. Sturiale, G. Calapai, G. Vico, G. Piedimonte, F. Salpietro, F. Tomasello (2002)
Beneficial effects of systemic administration of recombinant human erythropoietin in rabbits subjected to subarachnoid hemorrhageProceedings of the National Academy of Sciences of the United States of America, 99
T. Shingo, S. Sorokan, T. Shimazaki, S. Weiss (2001)
Erythropoietin Regulates the In Vitro and In Vivo Production of Neuronal Progenitors by Mammalian Forebrain Neural Stem CellsThe Journal of Neuroscience, 21
J. Fauchère, C. Dame, R. Vonthein, B. Koller, S. Arri, M. Wolf, H. Bucher (2008)
An Approach to Using Recombinant Erythropoietin for Neuroprotection in Very Preterm InfantsPediatrics, 122
G. Grasso, A. Sfacteria, F. Meli, V. Fodale, M. Buemi, D. Iacopino (2007)
Neuroprotection by erythropoietin administration after experimental traumatic brain injuryBrain Research, 1182
A. Anagnostou, Ziyao Liu, M. Steiner, K. Chin, Eun Lee, N. Kessimian, C. Noguchi (1994)
Erythropoietin receptor mRNA expression in human endothelial cells.Proceedings of the National Academy of Sciences of the United States of America, 91 9
H. Ehrenreich, K. Weissenborn, H. Prange, D. Schneider, C. Weimar, K. Wartenberg, P. Schellinger, M. Bohn, H. Bécker, Martin Wegrzyn, P. Jähnig, M. Herrmann, M. Knauth, M. Bähr, W. Heide, A. Wagner, S. Schwab, H. Reichmann, G. Schwendemann, R. Dengler, A. Kastrup, C. Bartels (2009)
Recombinant Human Erythropoietin in the Treatment of Acute Ischemic StrokeStroke, 40
K. Sakamaki (2004)
Regulation of endothelial cell death and its role in angiogenesis and vascular regression.Current neurovascular research, 1 4
H. Corwin, A. Gettinger, R. Pearl, M. Fink, M. Levy, M. Shapiro, M. Corwin, T. Colton (2002)
Efficacy of recombinant human erythropoietin in critically ill patients: a randomized controlled trial.JAMA, 288 22
Ş. Genç, Tolga Koroglu, K. Genc (2004)
Erythropoietin as a novel neuroprotectant.Restorative neurology and neuroscience, 22 2
G. Grasso, F. Graziano, A. Sfacteria, F. Carletti, F. Meli, R. Maugeri, M. Passalacqua, F. Certo, M. Fazio, M. Buemi, D. Iacopino (2009)
NEUROPROTECTIVE EFFECT OF ERYTHROPOIETIN AND DARBEPOETIN ALFA AFTER EXPERIMENTAL INTRACEREBRAL HEMORRHAGENeurosurgery, 65
Zhao (种), Jing-Qiong Kang, K. Maiese (2002)
Erythropoietin Is a Novel Vascular Protectant Through Activation of Akt1 and Mitochondrial Modulation of Cysteine ProteasesCirculation: Journal of the American Heart Association, 106
A. Nichol, D. Cooper (2009)
Can we improve neurological outcomes in severe traumatic brain injury? Something old (early prophylactic hypothermia) and something new (erythropoietin).Injury, 40 5
D. Thurman, C. Alverson, K. Dunn, Janet Guerrero, J. Sniezek (1999)
Traumatic brain injury in the United States: A public health perspective.The Journal of head trauma rehabilitation, 14 6
K. Maiese, Faqi Li, Zhao (种) (2005)
New avenues of exploration for erythropoietin.JAMA, 293 1
C. Hukkelhoven, E. Steyerberg, Anneke Rampen, E. Farace, J. Habbema, L. Marshall, G. Murray, A. Maas (2003)
Patient age and outcome following severe traumatic brain injury: an analysis of 5600 patients.Journal of neurosurgery, 99 4
ORIGINAL ARTICLE Erythropoiesis-Stimulating Agent Administration and Survival After Severe Traumatic Brain Injury A Prospective Study Peep Talving, MD, PhD; Thomas Lustenberger, MD; Kenji Inaba, MD; Lydia Lam, MD; Shahin Mohseni, MD; Linda Chan, PhD; Demetrios Demetriades, MD, PhD Objective: To validate previous findings of the effects injury, vital signs on admission, Abbreviated Injury Scale of erythropoiesis-stimulating agent (ESA) administra- scores, Injury Severity Scores, and specific intracranial in- tion following severe traumatic brain injury. juries. Patients who received ESA experienced signifi- cantly longer lengths of stay in the SICU (mean [SD], 16.1 Design: Prospective observational study of all patients [1.3] days vs 8.6 [0.8] days; P.001) and comparable SICU- with severe traumatic brain injury admitted to the sur- free days. There was no statistically significant difference gical intensive care unit (SICU) at our institution from in the incidence of major in-hospital complications includ- January 1, 2009, to December 31, 2010 (head Abbrevi- ing deep venous thrombosis and pulmonary embolism when ated Injury Scale score 3). Propensity scores were cal- comparing the 2 study cohorts. The Glasgow Coma Scale culated to match patients who received ESA within 30 mean [standard error of the mean] score was 3.0 [0.4] and days after
JAMA Surgery – American Medical Association
Published: Mar 1, 2012
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