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Ileal Tumor Causing Carcinoid Syndrome Without Hepatic Metastases

Ileal Tumor Causing Carcinoid Syndrome Without Hepatic Metastases Abstract To the Editor.—A recent case prompted us to review accumulating evidence that carcinoid syndrome may complicate gastrointestinal carcinoid tumors in the absence of liver metastases.1,2 Report of a Case.—A 51-year-old man with several years' history of diarrhea, facial flushing, and weight loss was found to have an elevated urinary 5-hydroxyindoleacetic acid level (50 mg/24 hr). Liver function test results and liver scan were normal. Arteriography suggested an ileal carcinoid. Liver biopsy showed a few granulomas consistent with allopurinol use but no evidence of metastatic disease. At laparotomy, an enlarged mass was found in the mesentery at the middle of the ileum, with extensive lymphadenopathy extending along the superior mesenteric artery to the periaortic nodes. The liver appeared normal during careful palpation and visualization. Following resection of an ileal carcinoid and much of the mesenteric tumor, diarrhea decreased, but the urinary 5-hydroxyindoleacetic acid level remained elevated. A computed References 1. Feldman JM, Jones RS: Carcinoid syndrome from gastrointestinal carcinoids without liver metastasis . Ann Surg 1982;196:33-37.Crossref 2. Strodel WE, Talpos G, Eckhauser F, et al: Surgical therapy for small-bowel carcinoid tumors . Arch Surg 1983;118:391-397.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Ileal Tumor Causing Carcinoid Syndrome Without Hepatic Metastases

ROSENBERG, JOEL M.; WELCH, JOHN P.
Archives of Surgery , Volume 119 (4) – Apr 1, 1984
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Ileal Tumor Causing Carcinoid Syndrome Without Hepatic Metastases

Abstract

Abstract To the Editor.—A recent case prompted us to review accumulating evidence that carcinoid syndrome may complicate gastrointestinal carcinoid tumors in the absence of liver metastases.1,2 Report of a Case.—A 51-year-old man with several years' history of diarrhea, facial flushing, and weight loss was found to have an elevated urinary 5-hydroxyindoleacetic acid level (50 mg/24 hr). Liver function test results and liver scan were normal. Arteriography suggested an ileal...
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References (2)

Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1984.01390160107021
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.—A recent case prompted us to review accumulating evidence that carcinoid syndrome may complicate gastrointestinal carcinoid tumors in the absence of liver metastases.1,2 Report of a Case.—A 51-year-old man with several years' history of diarrhea, facial flushing, and weight loss was found to have an elevated urinary 5-hydroxyindoleacetic acid level (50 mg/24 hr). Liver function test results and liver scan were normal. Arteriography suggested an ileal carcinoid. Liver biopsy showed a few granulomas consistent with allopurinol use but no evidence of metastatic disease. At laparotomy, an enlarged mass was found in the mesentery at the middle of the ileum, with extensive lymphadenopathy extending along the superior mesenteric artery to the periaortic nodes. The liver appeared normal during careful palpation and visualization. Following resection of an ileal carcinoid and much of the mesenteric tumor, diarrhea decreased, but the urinary 5-hydroxyindoleacetic acid level remained elevated. A computed References 1. Feldman JM, Jones RS: Carcinoid syndrome from gastrointestinal carcinoids without liver metastasis . Ann Surg 1982;196:33-37.Crossref 2. Strodel WE, Talpos G, Eckhauser F, et al: Surgical therapy for small-bowel carcinoid tumors . Arch Surg 1983;118:391-397.Crossref

Journal

Archives of Surgery – American Medical Association

Published: Apr 1, 1984

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