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Treatment Outcome in Recurrent Head and Neck Cancer

Treatment Outcome in Recurrent Head and Neck Cancer Abstract • One hundred cases of recurrent oral, pharyngeal, or laryngeal squamous cancer were reviewed to determine the contribution of retreatment of such lesions to overall survival. Thirty percent (8/27) of locally recurrent T1-2 primary lesions and 4% (1/28) of recurrent T3-4 lesions were cured by retreatment. Forty-five percent (5/11) of patients with conversion of N0 necks were salvaged, while no cures of neck recurrence after an earlier elective (four) or therapeutic (22) neck dissection were seen. Three of eight patients with isolated lung recurrence were salvaged. Patients benefiting most from retreatment were those with local recurrence of small primary lesions, conversion of a previously N0 neck, or isolated lung disease. Those with other types of recurrence were helped much less. (Arch Surg 114:39-42, 1979) References 1. Gilbert H, Kagan AR: Recurrence patterns in squamous cell carcinoma of the oral cavity, pharynx and larynx . J Surg Oncol 6:357-380, 1974.Crossref 2. Jesse RH, Fletcher GH, Lindberg RD, et al: Cancer of the head and neck , in Clark RL, Howe CG (ed): Cancer Patient Care at M. D. Anderson Hospital and Tumor Institute . Chicago, Year Book Medical Publishers Inc, 1976, pp 89-124. 3. Crews QE, Fletcher GH: Comparative evaluation of the sequential use of irradiation and surgery in primary tumors of the oral cavity, oropharynx, larynx and hypopharynx . Am J Roentgenol 111:73-77, 1971.Crossref 4. Fayos JV: Carcinoma of the endolarynx: Results of irradiation . Cancer 35:1525-1532, 1975.Crossref 5. Vermund H, Gollin FF: Role of radiotherapy in the treatment of cancer of the tongue . Cancer 32:333-345, 1973.Crossref 6. Botstein C, Silver C, Ariaratnam L: Treatment of carcinoma of the oral tongue by radium needle implantation . Am J Surg 132:523-524, 1976.Crossref 7. DeSanto LW, Lillie J, Devine K: Surgical salvage after radiation for laryngeal cancer . Laryngoscope 86:649-657, 1976.Crossref 8. Healy GB, Strong MS, Uchmakii A, et al: Carcinoma of the palatine arch: The rational of treatment selection . Am J Surg 132:498-503, 1976.Crossref 9. Whitehurst JO, Droulis CA: Surgical treatment of squamous cell carcinoma of the oral tongue . Arch Otolaryngol 103:212-215, 1977.Crossref 10. Chu W, Litwin S, Strawitz JG: A comparison of resection and radiation in the control of cancer within the mouth . Surg Gynecol Obstet 146:38-42, 1978. 11. Silver CE: Surgical management of neoplasms of the larynx, hypopharynx and cervical esophagus , in Current Problems in Surgery . Chicago, Year Book Medical Publishers Inc, 1977, vol 14. 12. Daly CJ, Strong EW: Carcinoma of the glottic larynx . Am J Surg 130:489-493, 1975.Crossref 13. Marquez A: Management of recurrent cancer of the head and neck , in Conley J (ed): Cancer of the Head and Neck . Washington, DC, Butterworth & Co, 1967, pp 56-61. 14. Williams RG: Recurrent head and neck cancer: The results of treatment . Br J Surg 61:691-697, 1974.Crossref 15. Jesse RH, Barkley HT, Lindberg RD, et al: Cancer of the oral cavity: Is elective neck dissection beneficial? Am J Surg 120:505-508, 1970.Crossref 16. Shah JP, Tollefson HR: Epidermoid carcinoma of the supraglottic larynx: Role of neck dissection in initial surgical treatment . Am J Surg 128:494-499, 1974.Crossref 17. Mendelson BC, Woods JE, Beahrs OH: Neck dissection in the treatment of carcinoma of the anterior two-thirds of the tongue . Surg Gynecol Obstet 143:75-80, 1976. 18. Fletcher GH: Textbook of Radiotherapy , ed 2. Philadelphia, Lea & Febiger, 1973, p 170. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Treatment Outcome in Recurrent Head and Neck Cancer

Archives of Surgery , Volume 114 (1) – Jan 1, 1979

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References (23)

Publisher
American Medical Association
Copyright
Copyright © 1979 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1979.01370250041008
Publisher site
See Article on Publisher Site

Abstract

Abstract • One hundred cases of recurrent oral, pharyngeal, or laryngeal squamous cancer were reviewed to determine the contribution of retreatment of such lesions to overall survival. Thirty percent (8/27) of locally recurrent T1-2 primary lesions and 4% (1/28) of recurrent T3-4 lesions were cured by retreatment. Forty-five percent (5/11) of patients with conversion of N0 necks were salvaged, while no cures of neck recurrence after an earlier elective (four) or therapeutic (22) neck dissection were seen. Three of eight patients with isolated lung recurrence were salvaged. Patients benefiting most from retreatment were those with local recurrence of small primary lesions, conversion of a previously N0 neck, or isolated lung disease. Those with other types of recurrence were helped much less. (Arch Surg 114:39-42, 1979) References 1. Gilbert H, Kagan AR: Recurrence patterns in squamous cell carcinoma of the oral cavity, pharynx and larynx . J Surg Oncol 6:357-380, 1974.Crossref 2. Jesse RH, Fletcher GH, Lindberg RD, et al: Cancer of the head and neck , in Clark RL, Howe CG (ed): Cancer Patient Care at M. D. Anderson Hospital and Tumor Institute . Chicago, Year Book Medical Publishers Inc, 1976, pp 89-124. 3. Crews QE, Fletcher GH: Comparative evaluation of the sequential use of irradiation and surgery in primary tumors of the oral cavity, oropharynx, larynx and hypopharynx . Am J Roentgenol 111:73-77, 1971.Crossref 4. Fayos JV: Carcinoma of the endolarynx: Results of irradiation . Cancer 35:1525-1532, 1975.Crossref 5. Vermund H, Gollin FF: Role of radiotherapy in the treatment of cancer of the tongue . Cancer 32:333-345, 1973.Crossref 6. Botstein C, Silver C, Ariaratnam L: Treatment of carcinoma of the oral tongue by radium needle implantation . Am J Surg 132:523-524, 1976.Crossref 7. DeSanto LW, Lillie J, Devine K: Surgical salvage after radiation for laryngeal cancer . Laryngoscope 86:649-657, 1976.Crossref 8. Healy GB, Strong MS, Uchmakii A, et al: Carcinoma of the palatine arch: The rational of treatment selection . Am J Surg 132:498-503, 1976.Crossref 9. Whitehurst JO, Droulis CA: Surgical treatment of squamous cell carcinoma of the oral tongue . Arch Otolaryngol 103:212-215, 1977.Crossref 10. Chu W, Litwin S, Strawitz JG: A comparison of resection and radiation in the control of cancer within the mouth . Surg Gynecol Obstet 146:38-42, 1978. 11. Silver CE: Surgical management of neoplasms of the larynx, hypopharynx and cervical esophagus , in Current Problems in Surgery . Chicago, Year Book Medical Publishers Inc, 1977, vol 14. 12. Daly CJ, Strong EW: Carcinoma of the glottic larynx . Am J Surg 130:489-493, 1975.Crossref 13. Marquez A: Management of recurrent cancer of the head and neck , in Conley J (ed): Cancer of the Head and Neck . Washington, DC, Butterworth & Co, 1967, pp 56-61. 14. Williams RG: Recurrent head and neck cancer: The results of treatment . Br J Surg 61:691-697, 1974.Crossref 15. Jesse RH, Barkley HT, Lindberg RD, et al: Cancer of the oral cavity: Is elective neck dissection beneficial? Am J Surg 120:505-508, 1970.Crossref 16. Shah JP, Tollefson HR: Epidermoid carcinoma of the supraglottic larynx: Role of neck dissection in initial surgical treatment . Am J Surg 128:494-499, 1974.Crossref 17. Mendelson BC, Woods JE, Beahrs OH: Neck dissection in the treatment of carcinoma of the anterior two-thirds of the tongue . Surg Gynecol Obstet 143:75-80, 1976. 18. Fletcher GH: Textbook of Radiotherapy , ed 2. Philadelphia, Lea & Febiger, 1973, p 170.

Journal

Archives of SurgeryAmerican Medical Association

Published: Jan 1, 1979

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