Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Discontinuance of Immunosuppression

Discontinuance of Immunosuppression This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.—Our experience at the University of Wisconsin permits me to agree with Dr Najarian's editorial comments on the article by Owens et al concerning the discontinuance of immunosuppression in renal transplant patients (Arch Surg 110:1450-1451, 1975). We have recently reviewed our immunosuppressive protocol at the University of Wisconsin, after finding that several patients had voluntarily stopped taking the drugs without informing the physician. Eight patients (five living related donor recipients and three cadaver recipients) stopped all immunosuppression against medical advice. This represents a 4% incidence of major lapses in immunosuppression, and is probably lower than the actual incidence. In addition, several other transplantation patients had their immunosuppressive therapy removed by medical advice due to severe infection or leukopenia. Two of the mixed leukocyte culture (MLC)-nonidentical living related donor recipients underwent severe rejection following cessation of immunosuppressive therapy; this was ultimately fatal to both. This occurred despite the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Discontinuance of Immunosuppression

Archives of Surgery , Volume 111 (5) – May 1, 1976

Discontinuance of Immunosuppression

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.—Our experience at the University of Wisconsin permits me to agree with Dr Najarian's editorial comments on the article by Owens et al concerning the discontinuance of immunosuppression in renal transplant patients (Arch Surg 110:1450-1451, 1975). We have recently reviewed our immunosuppressive protocol at the University of...
Loading next page...
 
/lp/american-medical-association/discontinuance-of-immunosuppression-wpGjXhbyr0

References (0)

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1976.01360230114029
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.—Our experience at the University of Wisconsin permits me to agree with Dr Najarian's editorial comments on the article by Owens et al concerning the discontinuance of immunosuppression in renal transplant patients (Arch Surg 110:1450-1451, 1975). We have recently reviewed our immunosuppressive protocol at the University of Wisconsin, after finding that several patients had voluntarily stopped taking the drugs without informing the physician. Eight patients (five living related donor recipients and three cadaver recipients) stopped all immunosuppression against medical advice. This represents a 4% incidence of major lapses in immunosuppression, and is probably lower than the actual incidence. In addition, several other transplantation patients had their immunosuppressive therapy removed by medical advice due to severe infection or leukopenia. Two of the mixed leukocyte culture (MLC)-nonidentical living related donor recipients underwent severe rejection following cessation of immunosuppressive therapy; this was ultimately fatal to both. This occurred despite the

Journal

Archives of SurgeryAmerican Medical Association

Published: May 1, 1976

There are no references for this article.