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R. Guttmann, C. Carpenter, R. Lindquist, J. Merrill (1967)
TREATMENT WITH HETEROLOGOUS ANTITHYMUS SERA: NEPHRITIS ASSOCIATED WITH MODIFICATION OF RENAL ALLOGRAFT REJECTION AND THE IMMUNE STATUS OF THE HOST TO THE FOREIGN PROTEINTransplantation, 5
Leo Sosula, Paul Beaumont, Frederick Hollows, K. Jonson (1972)
Dilatation and endothelial proliferation of retinal capillaries in streptozotocin-diabetic rats: quantitative electron microscopy.Investigative ophthalmology, 11 11
S. Greenberg (1962)
Glomerular changes in chronic alloxan diabetes.Archives of pathology, 73
R. Michel, R. Guttmann, J. Knaack, J. Klassen, J. Beudoin, D. Morehouse (1975)
Antilymphocyte globulin in renal transplantation: Nephrotic syndrome and infection as possible complications.Archives of surgery, 110 1
Ballinger Wf, P. Lacy (1972)
Transplantation of intact pancreatic islets in rats.Surgery, 72 2
S. Moskalewski (1965)
ISOLATION AND CULTURE OF THE ISLETS OF LANGERHANS OF THE GUINEA PIG.General and comparative endocrinology, 5
R. Lindquist, R. Guttmann, C. Carpenter, J. Merrill (1969)
NEPHRITIS INDUCED BY ANTILYMPHOCYTE SERUM AN ELECTRON MICROSCOPIC AND IMMUNOHISTOCHEMICAL STUDYTransplantation, 8
Stilmant MM Couser WG (1974)
Glomerular dysfunction associated with aging in the ratClin Res, 22
Gray BN (1973)
Transplantation of isolated pancreatic islet tissue in experimental diabetes: Current studies in the Sias Surgical LaboratoryLahey Clin Foundation Bull, 22
P. Kimmelstiel, C. Wilson (1936)
Intercapillary Lesions in the Glomeruli of the Kidney.The American journal of pathology, 12 1
Watkins E Gray BN (1973)
Reversion of streptozotocin-induced diabetes after syngeneic transplantation of isolated islets into the portal vascular bedClin Res, 21
R. Gates, M. Hunt, R. Smith, N. Lazarus (1972)
Return to normal of blood-glucose, plasma-insulin, and weight gain in New Zealand obese mice after implantation of islets of Langerhans.Lancet, 2 7777
S. Mauer, D. Sutherland, M. Steffes, R. Leonard, J. Najarian, A. Michael, D. Brown (1974)
Pancreatic Islet Transplantation: Effects on the Glomerular Lesions of Experimental Diabetes in the RatDiabetes, 23
S. Mauer, A. Michael, A. Fish, D. Brown (1972)
Spontaneous immunoglobulin and complement deposition in glomeruli of diabetic rats.Laboratory investigation; a journal of technical methods and pathology, 27 5
Abstract • Isolated pancreatic islets from Wistar-Lewis rats were transplanted into the liver of diabetic allogeneic recipients to assess ability to prevent diabetic renal and ophthalmic complications. At nine months, the diabetic animals without transplants showed significant increase in PAS-positive material in the renal glomerular mesangium and thickening of glomerular arterioles as compared with normal nondiabetic animals. New vessel formation was also significant in the retina and retinal capillary dilation. Animals in which diabetes had been corrected by early pancreatic islet transplantation were completely protected from these changes, showing no significant pathologic change when compared with normal animals. (Arch Surg 111:254-257, 1976) References 1. Moskalewski S: Isolation and culture of the islets of Langerhans of the guinea pig . Gen Comp Endocrinol 5:342-353, 1965.Crossref 2. Ballinger WF, Lacy PE: Transplantation of intact pancreatic islets in rats . Surgery 72:175-186, 1972. 3. Gates RJ, Hunt MI, Smith R, et al: Return to normal of blood-glucose, plasma-insulin, and weight gain in New Zealand obese mice after implantation of islets of Langerhans . Lancet 2:567-570, 1972.Crossref 4. Gray BN, Watkins E: Reversion of streptozotocin-induced diabetes after syngeneic transplantation of isolated islets into the portal vascular bed . Clin Res 21:979, 1973. 5. Gray BN: Transplantation of isolated pancreatic islet tissue in experimental diabetes: Current studies in the Sias Surgical Laboratory . Lahey Clin Foundation Bull 22:146-152, 1973. 6. Sosula L, Beaumont P, Hollows FC, et al: Dilatation and endothelial proliferation of retinal capillaries in streptozotocin-diabetic rats: Quantitative electron microscopy . Invest Ophthalmol 11:926-935, 1972. 7. Couser WG, Stilmant MM, Lowenstein LM: Glomerular dysfunction associated with aging in the rat . Clin Res 22:719A, 1974. 8. Mauer SM, Michael AF, Fish AJ, et al: Spontaneous immunoglobulin and complement deposition in glomeruli of diabetic rats . Lab Invest 27:488-494, 1972. 9. Mauer SM, Sutherland DE, Steffes MW, et al: Pancreatic islet transplantation: Effects on the glomerular lesions of experimental diabetes in the rat . Diabetes 23:748-753, 1974. 10. Guttman RD, Carpenter CB, Lindquist RR, et al: Treatment with heterologous antithymus sera: Nephritis associated with modification of renal allograft rejection and the immune status of the host to the foreign protein . Transplantation 5( (suppl) ):1115-1120, 1967.Crossref 11. Lindquist RR, Guttmann RD, Carpenter CB, et al: Nephritis induced by antilymphocyte serum: An electron microscopic and immunohistochemical study . Transplantation 8:545-557, 1969.Crossref 12. Michel RP, Guttmann RD, Knaack J, et al: Antilymphocyte globulin in renal transplantation: Nephrotic syndrome and infection as possible complications . Arch Surg 110:90-93, 1975.Crossref 13. Greenberg SR: Glomerular changes in chronic alloxan diabetes . Arch Pathol 73:263-273, 1962. 14. Kimmelstiel P, Wilson C: Intercapillary lesions in the glomeruli of the kidney . Am J Path 12:83-97, 1936.
Archives of Surgery – American Medical Association
Published: Mar 1, 1976
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