Pseudomembranous Colitis After the Prophylactic Use of Clindamycin

Abstract

Abstract Clindamycin has become a popular antibiotic choice following a number of surgical procedures. Clindamycin is a semi-synthetic, wide-spectrum antibiotic derived from the parent compound, lincomycin, and was introduced because it had far fewer gastrointestinal side-effects than lincomycin. A number of verified hospitalized cases of pseudomembranous colitis associated with oral clindamycin administration have been noted in the literature.1,2 Pseudomembranous colitis can be a very severe...