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G. Reynoso, T. Chu, D. Holyoke, E. Cohen, T. Nemoto, J. Wang, J. Chuang, P. Guinan, G. Murphy (1972)
Carcinoembryonic antigen in patients with different cancers.JAMA, 220 3
D. Thomson, J. Krupey, S. Freedman, P. Gold (1969)
The radioimmunoassay of circulating carcinoembryonic antigen of the human digestive system.Proceedings of the National Academy of Sciences of the United States of America, 64 1
R. Delwiche, N. Zamcheck, N. Marcon (1973)
Carcinoembryonic antigen in pancreatitisCancer, 31
et al Moore TL (1971)
Carcinoembryonic antigen assay in cancer of the colon and pancreas and other digestive tract disordersAm J Dig Dis, 16
Booth Sn, J. King, J. Leonard, Dykes Pw (1973)
Serum carcinoembryonic antigen in clinical disordersGut, 14
P. Gold, S. Freedman (1965)
DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUESThe Journal of Experimental Medicine, 121
S. Khoo, I. Mackay, Lo Gerfo, Krupey, Kupchik Moore, Keeley, Gottlieb Kupchik, Wilson Freedman, Gold, Khoo Warner, .. Information, Bettelheim Stevens, Leese, Turberville, Johns Alexander, Neville (1973)
Carcinoembryonic antigen in serum in diseases of the liver and pancreasJournal of Clinical Pathology, 26
P. Gerfo, J. Krupey, H. Hansen (1971)
Demonstration of an antigen common to several varieties of neoplasia.The New England journal of medicine, 285 3
(1972)
Joint National Cancer Institute of Canada/American Cancer Society Investigation: A collaborative study of a test for carcinoembryonic antigen (CEA) in the sera of patients with carcinoma of the colon and rectumCan Med Assoc J, 107
Chu TM Holyoke ED (1973)
Carcinoembryonic antigen (CEA) and gastrointestinal malignancyRev Surg, 30
T. Moore, P. Kantrowitz, N. Zamcheck (1972)
Carcinoembryonic antigen (CEA) in inflammatory bowel disease.JAMA, 222 8
P. Gold, S. Freedman (1965)
SPECIFIC CARCINOEMBRYONIC ANTIGENS OF THE HUMAN DIGESTIVE SYSTEMThe Journal of Experimental Medicine, 122
King J Dykes PW (1972)
Progress report: Carcinoembryonic antigen (CEA)Gut, 13
Hoffer PB McCartney WL (1973)
The role of the CEA as an adjunct in the diagnosis of colorectal carcinoma
et al Dhar P (1972)
Carcinoembryonic antigen (CEA) in colonic cancerJAMA, 221
P. Dhar, T. Moore, N. Zamcheck, H. Kupchik (1972)
Carcinoembryonic antigen (CEA) in colonic cancer. Use in preoperative and postoperative diagnosis and prognosis.JAMA, 221 1
N. Zamcheck, T. Moore, P. Dhar, H. Kupchik (1972)
Immunologic diagnosis and prognosis of human digestive-tract cancer: carcinoembryonic antigens.The New England journal of medicine, 286 2
P Dykes, J. King (1972)
Carcinoembryonic antigen (CEA).Gut, 13
Abstract Carcinoembryonic antigen (CEA) titers were determined in 137 patients with proven colorectal carcinoma preoperatively, and at routine intervals following operation. Preoperatively 65% of all patients had a positive test. The assay was positive in 14% with Dukes stage A tumors, 54% with B, 60% with C, and 79% with stage D lesions. Regional differences were noted with right-sided colon lesions having circulating CEA less frequently than left-sided colon tumors. The titer of CEA did not correlate directly either with the size or stage of the tumor, although marked elevations usually indicated metastatic disease. In patients with curative resections, CEA levels usually reverted to negative postoperatively, but became elevated again with recurrence of disease. Titers remained elevated in patients with D lesions who underwent palliative resection. References 1. Gold P, Freedman SO: Demonstration of tumor-specific antigens in human colonic carcinomata by immunological tolerance and absorption techniques . J Exp Med 121:439-462, 1965.Crossref 2. Gold P, Freedman SO: Specific carcinoembryonic antigens of the human digestive system . J Exp Med 122:467-481, 1965.Crossref 3. Thomson DMP, et al: The radioimmunoassay of circulating carcinoembryonic antigen of the human digestive system . Proc Natl Acad Sci USA 64:161-167, 1969.Crossref 4. LoGerfo P, Krupey J, Hansen HJ: Demonstration of an antigen common to several varieties of neoplasia . N Engl J Med 285:138-141, 1971.Crossref 5. Moore TL, et al: Carcinoembryonic antigen assay in cancer of the colon and pancreas and other digestive tract disorders . Am J Dig Dis 16:1-7, 1971.Crossref 6. Reynoso G, et al: Carcinoembryonic antigen in patients with different cancers . JAMA 220:361-365, 1972.Crossref 7. Moore TL, Kantrowitz PA, Zamchek N: Carcinoembryonic antigen (CEA) in inflammatory bowel disease . JAMA 222:944-947, 1972.Crossref 8. Joint National Cancer Institute of Canada/American Cancer Society Investigation: A collaborative study of a test for carcinoembryonic antigen (CEA) in the sera of patients with carcinoma of the colon and rectum . Can Med Assoc J 107:25-33, 1972. 9. Booth SN, et al: Serum carcinoembryonic antigen in clinical disorders . Gut 14:794-799, 1973.Crossref 10. Delwiche R, Zamchek N, Marcon N: Carcinoembryonic antigen in pancreatitis . Cancer 31:328-330, 1973.Crossref 11. Khoo SK, MacKay IR: Carcinoembryonic antigen in serum in diseases of the liver and pancreas . J Clin Pathol 26:470-475, 1973.Crossref 12. Carcinoembryonic antigen (CEA) test collaborative study. Read before the second conference of Hoffman LaRoche Inc, Nutley, NJ, 1972. 13. Zamchek N, et al: Immunologic diagnosis and prognosis of human digestive tract cancer: Carcinoembryonic antigen . N Engl J Med 286:83-86, 1972.Crossref 14. Dhar P, et al: Carcinoembryonic antigen (CEA) in colonic cancer . JAMA 221:31-35, 1972.Crossref 15. Dykes PW, King J: Progress report: Carcinoembryonic antigen (CEA) . Gut 13:1000-1012, 1972.Crossref 16. Holyoke ED, Chu TM, Murphy GP: Carcinoembryonic antigen (CEA) and gastrointestinal malignancy . Rev Surg 30:305-311, 1973. 17. McCartney WL, Hoffer PB, Paloyan D: The role of the CEA as an adjunct in the diagnosis of colorectal carcinoma . Presented as a scientific exhibit at the American College of Surgeons, Chicago, 1973.
Archives of Surgery – American Medical Association
Published: Aug 1, 1974
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