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Mobilization of Lipids by Perfusion of Pancreatic Juice in Hind Limbs of Dogs

Mobilization of Lipids by Perfusion of Pancreatic Juice in Hind Limbs of Dogs Abstract The infusion of pancreatic juice intravenously caused a drop in total lipid levels in serum. The intra-arterial perfusion of both nonactivated and activated pancreatic juice produced a rise in the perfusate levels of lipids. The mechanisms by which pancreatic juice causes a drop in systemic lipid levels while causing an elevation of lipid levels in the perfused hind limb remains unexplained. The perfusion of the juice produced no recognizable ill effects on the perfused limb. References 1. Wilder LW, DeJode LR, Milstein SW, et al: Mobilization of atherosclerotic plaque calcium with EDTA utilizing the isolation-perfusion principle . Surgery 52: 793-795, 1962. 2. Robertson AL: Enzymatic intimectomy of segmental vascular lesions . Circulation 38( (suppl 6) ):164, 1969. 3. Mansfield AO, Howard JM: In vitro mobilization of atherosclerotic plaque lipids: I. Incubation procedures . Arch Surg 92:407-413, 1966.Crossref 4. Mansfield AO, Howard JM: In vitro mobilization of atherosclerotic plaque lipids. II. Perfusion . Arch Surg 92:414-417, 1966.Crossref 5. Dimbiloglu ME, Appert HE, Howard JM, et al: Relative tolerance of the dog to intravenous infusions of pancreatic juice . Surgery 64:805-813, 1968. 6. Yacoub RS, Appert HE, Pairent FW, et al: Systemic manifestations of acute pancreatitis: Effects of the intravenous infusion of pancreatic juice . Arch Surg 99:47-53, 1969.Crossref 7. Yacoub RS, Appert HE, Howard JM: The metabolism of pancreatic amylase and lipase infused intravenously into dogs . Arch Surg 99:54-58, 1969.Crossref 8. Somogyi M: Blood diastase as an indicator of liver function . Proc Soc Exp Biol Med 32:538-540, 1934.Crossref 9. Cherry IS, Crandall LA Jr: The specificity of pancreatic lipase: Its appearance in the blood after pancreatic injury . Amer J Physiol 100:266-273, 1932. 10. Bragdon JH: Colorimetric determination of blood lipids . J Biol Chem 190:513-517, 1951. 11. Zak B, Dickenman RC, White EG, et al: Rapid estimation of free and total cholesterol . Amer J Clin Path 24:1307-1315, 1954. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Mobilization of Lipids by Perfusion of Pancreatic Juice in Hind Limbs of Dogs

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References (11)

Publisher
American Medical Association
Copyright
Copyright © 1970 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1970.01340280047012
Publisher site
See Article on Publisher Site

Abstract

Abstract The infusion of pancreatic juice intravenously caused a drop in total lipid levels in serum. The intra-arterial perfusion of both nonactivated and activated pancreatic juice produced a rise in the perfusate levels of lipids. The mechanisms by which pancreatic juice causes a drop in systemic lipid levels while causing an elevation of lipid levels in the perfused hind limb remains unexplained. The perfusion of the juice produced no recognizable ill effects on the perfused limb. References 1. Wilder LW, DeJode LR, Milstein SW, et al: Mobilization of atherosclerotic plaque calcium with EDTA utilizing the isolation-perfusion principle . Surgery 52: 793-795, 1962. 2. Robertson AL: Enzymatic intimectomy of segmental vascular lesions . Circulation 38( (suppl 6) ):164, 1969. 3. Mansfield AO, Howard JM: In vitro mobilization of atherosclerotic plaque lipids: I. Incubation procedures . Arch Surg 92:407-413, 1966.Crossref 4. Mansfield AO, Howard JM: In vitro mobilization of atherosclerotic plaque lipids. II. Perfusion . Arch Surg 92:414-417, 1966.Crossref 5. Dimbiloglu ME, Appert HE, Howard JM, et al: Relative tolerance of the dog to intravenous infusions of pancreatic juice . Surgery 64:805-813, 1968. 6. Yacoub RS, Appert HE, Pairent FW, et al: Systemic manifestations of acute pancreatitis: Effects of the intravenous infusion of pancreatic juice . Arch Surg 99:47-53, 1969.Crossref 7. Yacoub RS, Appert HE, Howard JM: The metabolism of pancreatic amylase and lipase infused intravenously into dogs . Arch Surg 99:54-58, 1969.Crossref 8. Somogyi M: Blood diastase as an indicator of liver function . Proc Soc Exp Biol Med 32:538-540, 1934.Crossref 9. Cherry IS, Crandall LA Jr: The specificity of pancreatic lipase: Its appearance in the blood after pancreatic injury . Amer J Physiol 100:266-273, 1932. 10. Bragdon JH: Colorimetric determination of blood lipids . J Biol Chem 190:513-517, 1951. 11. Zak B, Dickenman RC, White EG, et al: Rapid estimation of free and total cholesterol . Amer J Clin Path 24:1307-1315, 1954.

Journal

Archives of SurgeryAmerican Medical Association

Published: Oct 1, 1970

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