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Correction of Heart Defects With Cardiopulmonary Bypass: Report of a Case Using Frozen Autologous Blood

Correction of Heart Defects With Cardiopulmonary Bypass: Report of a Case Using Frozen Autologous... Abstract OBTAINING an adequate quantity of compatible blood for major surgical procedures in individuals with unusual blood groups and rare serum antibodies is a longstanding problem of blood banks and surgeons. Corrective cardiac surgery employing complete cardiopulmonary bypass and the disc oxygenator poses a particularly demanding example of this problem. Autologous blood in small quantities has been used clinically when anticipated blood requirements are minimal and the blood can be obtained from the patient within two to three weeks prior to surgery, this limit being imposed by conventional blood preservation methods. Recent advances in cryobiology and the preservation of blood in the frozen state at −85 C for prolonged periods of time suggested a new approach to the problem of major surgery in the rare blood group individuals. This report describes the successful use of frozen autologous blood alone during surgical correction on cardiopulmonary bypass of an interventricular septal defect with References 1. Race, R.R., and Sanger, R.: Blood Groups in Man , ed 4, Oxford: Blackwell Scientific Publications, 1962, pp 327-335. 2. Jenkins, W.J., et al: The 1 Antigen and Antibody , Vox Sang 5:97, 1960.Crossref 3. Huggins, CE.: Frozen Blood , Ann Surg 160:643, 1964.Crossref 4. Huggins, C.E., and Grove-Rasmussen, M.: Advances in Blood Preservation , Postgrad Med 37:557, 1965. 5. Huggins, C.E.: Frozen Blood: Theory and Practice , JAMA 193:941, 1965.Crossref 6. Grove-Rasmussen, M.: Routine Compatibility Testing: Standards of the AABB as Applied to Compatibility Tests , Transfusion 4:200, 1964.Crossref 7. Wiener, A.S., et al: Type-Specific Cold Auto-Antibodies as a Cause of Acquired Hemolytic Anemia and Hemolytic Transfusion Reaction: Biologic Test With Bovine Red Cells , Ann Intern Med 44:221, 1956.Crossref 8. Huggins, C.E.: Frozen Blood: Clinical Experience , Surgery 60:771966. 9. Beall, A.C., Jr., et al: Open Heart Surgery Without Blood Transfusion , Arch Surg 94:567, 1967.Crossref 10. Huggins, C.E.: Frozen Blood: Principles of Practical Preservation , Monogr Surg Sci 3:133, 1966. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Correction of Heart Defects With Cardiopulmonary Bypass: Report of a Case Using Frozen Autologous Blood

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References (10)

Publisher
American Medical Association
Copyright
Copyright © 1968 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1968.01330200155033
Publisher site
See Article on Publisher Site

Abstract

Abstract OBTAINING an adequate quantity of compatible blood for major surgical procedures in individuals with unusual blood groups and rare serum antibodies is a longstanding problem of blood banks and surgeons. Corrective cardiac surgery employing complete cardiopulmonary bypass and the disc oxygenator poses a particularly demanding example of this problem. Autologous blood in small quantities has been used clinically when anticipated blood requirements are minimal and the blood can be obtained from the patient within two to three weeks prior to surgery, this limit being imposed by conventional blood preservation methods. Recent advances in cryobiology and the preservation of blood in the frozen state at −85 C for prolonged periods of time suggested a new approach to the problem of major surgery in the rare blood group individuals. This report describes the successful use of frozen autologous blood alone during surgical correction on cardiopulmonary bypass of an interventricular septal defect with References 1. Race, R.R., and Sanger, R.: Blood Groups in Man , ed 4, Oxford: Blackwell Scientific Publications, 1962, pp 327-335. 2. Jenkins, W.J., et al: The 1 Antigen and Antibody , Vox Sang 5:97, 1960.Crossref 3. Huggins, CE.: Frozen Blood , Ann Surg 160:643, 1964.Crossref 4. Huggins, C.E., and Grove-Rasmussen, M.: Advances in Blood Preservation , Postgrad Med 37:557, 1965. 5. Huggins, C.E.: Frozen Blood: Theory and Practice , JAMA 193:941, 1965.Crossref 6. Grove-Rasmussen, M.: Routine Compatibility Testing: Standards of the AABB as Applied to Compatibility Tests , Transfusion 4:200, 1964.Crossref 7. Wiener, A.S., et al: Type-Specific Cold Auto-Antibodies as a Cause of Acquired Hemolytic Anemia and Hemolytic Transfusion Reaction: Biologic Test With Bovine Red Cells , Ann Intern Med 44:221, 1956.Crossref 8. Huggins, C.E.: Frozen Blood: Clinical Experience , Surgery 60:771966. 9. Beall, A.C., Jr., et al: Open Heart Surgery Without Blood Transfusion , Arch Surg 94:567, 1967.Crossref 10. Huggins, C.E.: Frozen Blood: Principles of Practical Preservation , Monogr Surg Sci 3:133, 1966.

Journal

Archives of SurgeryAmerican Medical Association

Published: Feb 1, 1968

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