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John Gibson, William Evans (1937)
CLINICAL STUDIES OF THE BLOOD VOLUME. I. CLINICAL APPLICATION OF A METHOD EMPLOYING THE AZO DYE "EVANS BLUE" AND THE SPECTROPHOTOMETER.The Journal of clinical investigation, 16 3
K. Sterling, S. Gray (1950)
Determination of the circulating red cell volume in man by radioactive chromium.The Journal of clinical investigation, 29 12
J. Gibson (1939)
CLINICAL STUDIES OF THE BLOOD VOLUME. VI. CHANGES IN BLOOD VOLUME IN PERNICIOUS ANEMIA IN RELATION TO THE HEMATOPOIETIC RESPONSE TO INTRA-MUSCULAR LIVER EXTRACT THERAPY.The Journal of clinical investigation, 18 4
J. Williams, J. Fine (1961)
Measurement of blood volume with a new apparatus.The New England journal of medicine, 264
Abstract Introduction In recent years, much has been learned of fluid and electrolyte shifts which occur in the body. Accurate electrolyte determinations have been made possible with the development of the flame photometer and the Van Slyke machine. Likewise, blood volume determinations have become popular since the introduction of dye and radioisotope techniques for measurement.The usefulness of an accurate, convenient method for determining blood volume, adaptable to routine clinical use, is evident. Gregersen and Rawson3 defined the methodologic pitfalls which lead to serious errors with the dye techniques. The use of radioisotopes, though more accurate, requires the service of semiskilled personnel.Instruments available for measuring radioisotopes require that several steps be included in the technique. These volumetric and dilution steps not only are time consuming, but also result in an increase in the experimental error of the determination.A recently introduced instrument, the Volemetron, described by Williams and Fine, References 1. K=value for Evans blue=40.5. 2. Gibson, J. G., and Evans, W. A., Jr.: J. Clin. Invest. 16:301, 1937.Crossref 3. Gibson, J. G.: J. Clin. Invest. 18:401, 1939.Crossref 4. Gregersen, M. I., and Rawson, R. A.: Physiol. Rev. 39:307, 1959. 5. Sterling, K., and Gray, S. J.: J. Clin. Invest. 29:1614, 1950.Crossref 6. Williams, J. A., and Fine, J.: New Engl. J. Med. 264:842, 1961.Crossref
Archives of Surgery – American Medical Association
Published: Jan 1, 1963
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