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Comparative Study of New Device for Measuring Blood Volume

Comparative Study of New Device for Measuring Blood Volume Abstract Introduction In recent years, much has been learned of fluid and electrolyte shifts which occur in the body. Accurate electrolyte determinations have been made possible with the development of the flame photometer and the Van Slyke machine. Likewise, blood volume determinations have become popular since the introduction of dye and radioisotope techniques for measurement.The usefulness of an accurate, convenient method for determining blood volume, adaptable to routine clinical use, is evident. Gregersen and Rawson3 defined the methodologic pitfalls which lead to serious errors with the dye techniques. The use of radioisotopes, though more accurate, requires the service of semiskilled personnel.Instruments available for measuring radioisotopes require that several steps be included in the technique. These volumetric and dilution steps not only are time consuming, but also result in an increase in the experimental error of the determination.A recently introduced instrument, the Volemetron, described by Williams and Fine, References 1. K=value for Evans blue=40.5. 2. Gibson, J. G., and Evans, W. A., Jr.: J. Clin. Invest. 16:301, 1937.Crossref 3. Gibson, J. G.: J. Clin. Invest. 18:401, 1939.Crossref 4. Gregersen, M. I., and Rawson, R. A.: Physiol. Rev. 39:307, 1959. 5. Sterling, K., and Gray, S. J.: J. Clin. Invest. 29:1614, 1950.Crossref 6. Williams, J. A., and Fine, J.: New Engl. J. Med. 264:842, 1961.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Comparative Study of New Device for Measuring Blood Volume

Archives of Surgery , Volume 86 (1) – Jan 1, 1963

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1963 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1963.01310070166022
Publisher site
See Article on Publisher Site

Abstract

Abstract Introduction In recent years, much has been learned of fluid and electrolyte shifts which occur in the body. Accurate electrolyte determinations have been made possible with the development of the flame photometer and the Van Slyke machine. Likewise, blood volume determinations have become popular since the introduction of dye and radioisotope techniques for measurement.The usefulness of an accurate, convenient method for determining blood volume, adaptable to routine clinical use, is evident. Gregersen and Rawson3 defined the methodologic pitfalls which lead to serious errors with the dye techniques. The use of radioisotopes, though more accurate, requires the service of semiskilled personnel.Instruments available for measuring radioisotopes require that several steps be included in the technique. These volumetric and dilution steps not only are time consuming, but also result in an increase in the experimental error of the determination.A recently introduced instrument, the Volemetron, described by Williams and Fine, References 1. K=value for Evans blue=40.5. 2. Gibson, J. G., and Evans, W. A., Jr.: J. Clin. Invest. 16:301, 1937.Crossref 3. Gibson, J. G.: J. Clin. Invest. 18:401, 1939.Crossref 4. Gregersen, M. I., and Rawson, R. A.: Physiol. Rev. 39:307, 1959. 5. Sterling, K., and Gray, S. J.: J. Clin. Invest. 29:1614, 1950.Crossref 6. Williams, J. A., and Fine, J.: New Engl. J. Med. 264:842, 1961.Crossref

Journal

Archives of SurgeryAmerican Medical Association

Published: Jan 1, 1963

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