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Treatment of Venous Thrombosis and Its Sequelae

Treatment of Venous Thrombosis and Its Sequelae Abstract Venous thrombosis affects numerous sites in human beings, and signs and symptoms resulting from its presence are extremely variable. Small veins, large veins, minor tributaries, and major stems show protean effects when they are involved by thrombosis. The causative factors, too, are numerous and extremely variable—blood stasis, changes in known and unknown coagulation factors and trauma, malignancy, systemic diseases: cardiac, pulmonary, hepatic, hematogenous, vascular. These features are important, but the objectives of this discussion will be confined mainly to treatment. A classification of venous thrombosis may be very useful in discussing the practical aspects of treatment, and with this in view the following is a classification based on anatomic location, degree of involvement, and presence or absence of infection in thrombus. Classification A. Superficial vein thrombosisB. Deep vein thrombosisMildSeverePhlegmasia alba dolensPhlegmasia cerulea dolensC. Septic thrombosisUsing this classification it is possible to segregate the References 1. Merck Sharp & Dohme. 2. Ortho Pharmaceutical Corp. 3. Cohen, S. I., and Warren, R.: Fibrinolysis , New Engl. J. Med. 264:79-84, 1961.Crossref 4. Cohen, S. I., and Warren, R.: Fibrinolysis (Concluded) , New Engl. J. Med. 264:128-134, 1961.Crossref 5. Collins, C. G., and Ayers, W. B.: Suppurative Pelvic Thrombophlebitis: III. Surgical Technique , Surgery 30:319-328, 1951. 6. Haimovici, H.: Gangrene of the Extremities of Venous Origin , Circulation 1:225-240, 1950.Crossref 7. Homans, J.: Deep Quiet Venous Thrombosis in the Lower Limb: Preferred Levels for Interruption of Veins; Iliac Sector or Ligation , Surg. Gynec. Obstet. 79:70-82, 1944. 8. Jorpes, J. E.: Anticoagulant Therapy in Thrombosis , Surg. Gynec. Obstet. 84:677-681, 1947. 9. Mahorner, H.: A New Method of Management for Thrombosis of Deep Veins of the Extremities: Thrombectomy, Restoration of the Lumen and Heparinization , Amer. Surg. 20:487-498, 1954. 10. Mahorner, H.; Castleberry, J. W., and Coleman, W. O.: Attempts to Restore Function in Major Veins Which are the Site of Massive Thrombosis , Ann. Surg. 146:510-522, 1957.Crossref 11. Moser, K. M.: Thrombolysis with Fibrinolysin (Plasmin): New Therapeutic Approach to Thromboembolism , J.A.M.A. 167:1695-1704, 1958.Crossref 12. Moser, K. M., and Hajjar, G. C.: The Combined Use of Fibrinolytic and Anticoagulant Agents , Amer. J. Cardiol. 6:496-502, 1960.Crossref 13. Sawyer, W. D.; Alkjaersig, N.; Fletcher, A. P., and Sherry, S.: Thrombolytic Therapy , Arch. Intern. Med. 107:274-289, 1961.Crossref 14. Serio, V.: Über Blutdruck und Blutkreislauf in den Krampfadern der unteren Extremitäten , Acta Chir. Scand. 80:41-81, 1937 15. Acta Soc. Med. Fenn. Duodecim 27:1-9, 1939. 16. Stürup, H., and Højensgard, I. C.: Venous Pressure in Varicose Veins in Patients with Incompetent Communicating Veins: A Study of the Statics and Dynamics of the Venous System of the Lower Extremity Under Pathological Conditions , Acta Chir. Scand. 99:518-525, 1950. 17. Warren, R.; White, E. A., and Belcher, C. D.: Venous Pressures in the Saphenous System in Normal, Varicose, and Postphlebitic Extremities , Surgery 26:435-445, 1949. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Treatment of Venous Thrombosis and Its Sequelae

Archives of Surgery , Volume 85 (3) – Sep 1, 1962

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References (18)

Publisher
American Medical Association
Copyright
Copyright © 1962 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1962.01310030003001
Publisher site
See Article on Publisher Site

Abstract

Abstract Venous thrombosis affects numerous sites in human beings, and signs and symptoms resulting from its presence are extremely variable. Small veins, large veins, minor tributaries, and major stems show protean effects when they are involved by thrombosis. The causative factors, too, are numerous and extremely variable—blood stasis, changes in known and unknown coagulation factors and trauma, malignancy, systemic diseases: cardiac, pulmonary, hepatic, hematogenous, vascular. These features are important, but the objectives of this discussion will be confined mainly to treatment. A classification of venous thrombosis may be very useful in discussing the practical aspects of treatment, and with this in view the following is a classification based on anatomic location, degree of involvement, and presence or absence of infection in thrombus. Classification A. Superficial vein thrombosisB. Deep vein thrombosisMildSeverePhlegmasia alba dolensPhlegmasia cerulea dolensC. Septic thrombosisUsing this classification it is possible to segregate the References 1. Merck Sharp & Dohme. 2. Ortho Pharmaceutical Corp. 3. Cohen, S. I., and Warren, R.: Fibrinolysis , New Engl. J. Med. 264:79-84, 1961.Crossref 4. Cohen, S. I., and Warren, R.: Fibrinolysis (Concluded) , New Engl. J. Med. 264:128-134, 1961.Crossref 5. Collins, C. G., and Ayers, W. B.: Suppurative Pelvic Thrombophlebitis: III. Surgical Technique , Surgery 30:319-328, 1951. 6. Haimovici, H.: Gangrene of the Extremities of Venous Origin , Circulation 1:225-240, 1950.Crossref 7. Homans, J.: Deep Quiet Venous Thrombosis in the Lower Limb: Preferred Levels for Interruption of Veins; Iliac Sector or Ligation , Surg. Gynec. Obstet. 79:70-82, 1944. 8. Jorpes, J. E.: Anticoagulant Therapy in Thrombosis , Surg. Gynec. Obstet. 84:677-681, 1947. 9. Mahorner, H.: A New Method of Management for Thrombosis of Deep Veins of the Extremities: Thrombectomy, Restoration of the Lumen and Heparinization , Amer. Surg. 20:487-498, 1954. 10. Mahorner, H.; Castleberry, J. W., and Coleman, W. O.: Attempts to Restore Function in Major Veins Which are the Site of Massive Thrombosis , Ann. Surg. 146:510-522, 1957.Crossref 11. Moser, K. M.: Thrombolysis with Fibrinolysin (Plasmin): New Therapeutic Approach to Thromboembolism , J.A.M.A. 167:1695-1704, 1958.Crossref 12. Moser, K. M., and Hajjar, G. C.: The Combined Use of Fibrinolytic and Anticoagulant Agents , Amer. J. Cardiol. 6:496-502, 1960.Crossref 13. Sawyer, W. D.; Alkjaersig, N.; Fletcher, A. P., and Sherry, S.: Thrombolytic Therapy , Arch. Intern. Med. 107:274-289, 1961.Crossref 14. Serio, V.: Über Blutdruck und Blutkreislauf in den Krampfadern der unteren Extremitäten , Acta Chir. Scand. 80:41-81, 1937 15. Acta Soc. Med. Fenn. Duodecim 27:1-9, 1939. 16. Stürup, H., and Højensgard, I. C.: Venous Pressure in Varicose Veins in Patients with Incompetent Communicating Veins: A Study of the Statics and Dynamics of the Venous System of the Lower Extremity Under Pathological Conditions , Acta Chir. Scand. 99:518-525, 1950. 17. Warren, R.; White, E. A., and Belcher, C. D.: Venous Pressures in the Saphenous System in Normal, Varicose, and Postphlebitic Extremities , Surgery 26:435-445, 1949.

Journal

Archives of SurgeryAmerican Medical Association

Published: Sep 1, 1962

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