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The Synthetic Vascular Graft: New Concepts, New Materials

The Synthetic Vascular Graft: New Concepts, New Materials Abstract From the results of our previous studies,4,5 in over 350 experimental pigs and dogs we have been able to establish the following reasonable specifications for the ideal synthetic vascular graft material. The synthetic graft wall should have the following characteristics: 1. No toxicity, no allergenic potential. "Biological reactivity," over a range varying from that of lead and glass to that of Teflon, does not appear to be a limiting factor in the ultimate fate of the synthetic graft. 2. No deterioration of the synthetic fiber upon biological implantation for prolonged periods of time. This specification is not met by the use of Ivalon, nylon, or Orlon. Vinyon-N, polyester (Dacron), polytetrafluoroethylene (Teflon), high-density polyethylene (Marlex), and polypropylene appear to meet this specification. 3. A material with desirable mechanical handling of properties will be: A. Scrunchable. This term is meant to imply the ability of a graft to readjust its wall References 1. Sawyer, P. N., and Valmont, I.: Evidence of Active Ion Transport Across Large Canine Blood-Vessel Walls , Nature 189:470-472, 1961.Crossref 2. Sawyer, P. N., and Wesolowski, S. A.: Electric Current of Injured Tissue and Vascular Occlusion , Ann. Surg. 153:34-42, 1961.Crossref 3. Voorhees, A.: Discussion at Meeting of the New York Society for Cardiovascular Surgery, 1961. 4. Wesolowski, S. A.: Evaluation of Tissue and Prosthetic Vascular Grafts , Springfield, Ill., Charles C Thomas, Publisher, 1961. 5. Wesolowski, S. A.; Fries, C. C.; Karlson, K. E.; DeBakey, M. E., and Sawyer, P. N.: Porosity-Primary Determinant of Ultimate Fate of Synthetic Vascular Grafts , Surgery 50:91-96, 1961. 6. Wesolowski, S. A.; Fries, C. C., and Sawyer, P. N.: The Unimportance of Biological Reactivity of the Vascular Graft Wall , Trans. Am. Soc. Art. Int. Organs. 7:296-300, 1961. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

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References (5)

Publisher
American Medical Association
Copyright
Copyright © 1962 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1962.01300190060009
Publisher site
See Article on Publisher Site

Abstract

Abstract From the results of our previous studies,4,5 in over 350 experimental pigs and dogs we have been able to establish the following reasonable specifications for the ideal synthetic vascular graft material. The synthetic graft wall should have the following characteristics: 1. No toxicity, no allergenic potential. "Biological reactivity," over a range varying from that of lead and glass to that of Teflon, does not appear to be a limiting factor in the ultimate fate of the synthetic graft. 2. No deterioration of the synthetic fiber upon biological implantation for prolonged periods of time. This specification is not met by the use of Ivalon, nylon, or Orlon. Vinyon-N, polyester (Dacron), polytetrafluoroethylene (Teflon), high-density polyethylene (Marlex), and polypropylene appear to meet this specification. 3. A material with desirable mechanical handling of properties will be: A. Scrunchable. This term is meant to imply the ability of a graft to readjust its wall References 1. Sawyer, P. N., and Valmont, I.: Evidence of Active Ion Transport Across Large Canine Blood-Vessel Walls , Nature 189:470-472, 1961.Crossref 2. Sawyer, P. N., and Wesolowski, S. A.: Electric Current of Injured Tissue and Vascular Occlusion , Ann. Surg. 153:34-42, 1961.Crossref 3. Voorhees, A.: Discussion at Meeting of the New York Society for Cardiovascular Surgery, 1961. 4. Wesolowski, S. A.: Evaluation of Tissue and Prosthetic Vascular Grafts , Springfield, Ill., Charles C Thomas, Publisher, 1961. 5. Wesolowski, S. A.; Fries, C. C.; Karlson, K. E.; DeBakey, M. E., and Sawyer, P. N.: Porosity-Primary Determinant of Ultimate Fate of Synthetic Vascular Grafts , Surgery 50:91-96, 1961. 6. Wesolowski, S. A.; Fries, C. C., and Sawyer, P. N.: The Unimportance of Biological Reactivity of the Vascular Graft Wall , Trans. Am. Soc. Art. Int. Organs. 7:296-300, 1961.

Journal

Archives of SurgeryAmerican Medical Association

Published: Jan 1, 1962

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