Access the full text.
Sign up today, get DeepDyve free for 14 days.
H. C. Engell (1955)
Cancer Cells in the Circulating BloodActa chir. scandinav.
E. R. Fisher (1955)
The Cytologic Demonstration and Significance of Tumor Cells in the Mesenteric Venous Blood in Patients with Colorectal CarcinomaSurg. Gynec, & Obst., 100
L. Aschoff (1906)
Ein Fall von MyelomMünchen. med. Wchnschr., 53
G. E. Moore , A. Sandberg (1957)
Clinical and Experimental Observations of the Occurrence and Fate of Tumor Cells in the Blood StreamAnn. Surg., 146
T. R. Ashworth (1869)
A Case of Cancer in Which Cells Similar to Those in the Tumours Were Seen in the Blood After DeathAustralian M. J., 14
K. Schleip (1906)
Zur Diagnose von Knochenmarkstumoren aus dem BlutbefundeZtschr. klin. Med., 59
S. Roberts , A. Watne, R. McGrath, E. McGrew (1958)
Technique and Results of Isolation of Cancer Cells from the Circulating BloodA. M. A. Arch. Surg., 76
G. R. Ward (1913)
The Blood in Cancer with Bone MetastasesLancet, 1
W. H. Cole , D. Packard (1954)
Carcinoma of the Colon with Special Reference to Prevention of RecurrenceJ. A. M. A., 155
Abstract Although it is generally believed that malignant tumors in children are associated with a poorer prognosis than are malignancies in adults, the reasons for such an assumption, other than clinical observation, have not been made clear. Vascular dissemination of cancer in children may be of importance in this regard. This study is concerned with that aspect of the vascular dissemination dealing with the carriage of cancer cells in the circulating blood of children, and the occurrence of these cells during an operative procedure. Historical Review Since 1869, when Ashworth1 reported cells in the blood which appeared to be similar to the cells of the patient's multiple malignant skin tumors, several investigators2-4 have reported "abnormal cells" in the blood stream.In 1954 Cole, Packard, and Southwick,5 using the Papanicolaou slain, reported cancer cells in the fluid perfused through the major artery and collected from the vein of a References 1. Ashworth, T. R.: A Case of Cancer in Which Cells Similar to Those in the Tumours Were Seen in the Blood After Death , Australian M. J. 14:146, 1869. 2. Schleip, K.: Zur Diagnose von Knochenmarkstumoren aus dem Blutbefunde , Ztschr. klin. Med. 59:261, 1906. 3. Aschoff, L.: Ein Fall von Myelom , München. med. Wchnschr. 53:337, 1906. 4. Ward, G. R.: The Blood in Cancer with Bone Metastases , Lancet 1:676, 1913.Crossref 5. Cole, W. H.; Packard, D., and Southwick, H. W.: Carcinoma of the Colon with Special Reference to Prevention of Recurrence , J. A. M. A. 155:1549, 1954.Crossref 6. Fisher, E. R., and Turnbull, R. B., Jr.: The Cytologic Demonstration and Significance of Tumor Cells in the Mesenteric Venous Blood in Patients with Colorectal Carcinoma , Surg. Gynec, & Obst. 100:102, 1955. 7. Engell, H. C.: Cancer Cells in the Circulating Blood , Acta chir. scandinav. , (Supp. 201) , 1955. 8. Moore, G. E.; Sandberg, A., and Schubarg, J. R.: Clinical and Experimental Observations of the Occurrence and Fate of Tumor Cells in the Blood Stream , Ann. Surg. 146:580, 1957. 9. Roberts, S.; Watne, A.; McGrath, R.; McGrew, E., and Cole, W. H.: Technique and Results of Isolation of Cancer Cells from the Circulating Blood , A. M. A. Arch. Surg. 76:334, 1958. 10. Roberts, S. S.; Watne, A.; McGrath, R.; McGrew, E., and Cole, W. H.: The Response of Cancer Cells in the Circulating Blood to Surgical Stress and Chemotherapy, S. Forum, to be published.
A.M.A. Archives Surgery – American Medical Association
Published: May 1, 1959
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.