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Cross Clamping of the Descending Thoracic Aorta: Effect on Blood Flow, Blood Pressure, and Survival; an Experimental Study

Cross Clamping of the Descending Thoracic Aorta: Effect on Blood Flow, Blood Pressure, and... Abstract Occlusion of the thoracic aorta for prolonged periods of time is often followed by ischemic damage or death. Considerable variation in the ability of animals and man to withstand this insult has been recorded in the literature. Since the amount of collateral blood flow reaching the lower part of the body during the time of aortic cross clamping is probably one of the most important factors contributing to the animal's eventual survival, it seemed worth while to study some of the circumstances that might affect this mechanism. In this report, the influence of the level and extent of aortic occlusion relative to the amount of collateral blood flow serving the tissues below the clamps was studied. Methods Mongrel dogs were used. Anesthesia was induced and maintained by the intravenous administration of 3 to 4 ml. of 5% thiopental sodium. An endotracheal tube was passed, and oxygen was administered by means References 1. King, H., and Bounous, G.: Cardiac Input in Hypothermia, Surg. Gynec. & Obst., to be published. 2. Pontius, R. G.; Brockman, H. LeR.; Hardy E. G.; Cooley, D. A., and De Bakey, M. E.: The Use of Hypothermia in the Prevention of Paraplegia Following Temporary Aortic Occlusion: Experimental Observations , Surgery 36:33, 1954. 3. De Bakey, M. E., in discussion on King, H., and Shumacker, H. B.: Mechanical By-Pass During Thoracic Aortic Cross-Clamping , J. Thoracic Surg. 34:485-499, 1957, p. 498. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives Surgery American Medical Association

Cross Clamping of the Descending Thoracic Aorta: Effect on Blood Flow, Blood Pressure, and Survival; an Experimental Study

A.M.A. Archives Surgery , Volume 78 (4) – Apr 1, 1959

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References (2)

Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved.
ISSN
0096-6908
DOI
10.1001/archsurg.1959.04320040015006
Publisher site
See Article on Publisher Site

Abstract

Abstract Occlusion of the thoracic aorta for prolonged periods of time is often followed by ischemic damage or death. Considerable variation in the ability of animals and man to withstand this insult has been recorded in the literature. Since the amount of collateral blood flow reaching the lower part of the body during the time of aortic cross clamping is probably one of the most important factors contributing to the animal's eventual survival, it seemed worth while to study some of the circumstances that might affect this mechanism. In this report, the influence of the level and extent of aortic occlusion relative to the amount of collateral blood flow serving the tissues below the clamps was studied. Methods Mongrel dogs were used. Anesthesia was induced and maintained by the intravenous administration of 3 to 4 ml. of 5% thiopental sodium. An endotracheal tube was passed, and oxygen was administered by means References 1. King, H., and Bounous, G.: Cardiac Input in Hypothermia, Surg. Gynec. & Obst., to be published. 2. Pontius, R. G.; Brockman, H. LeR.; Hardy E. G.; Cooley, D. A., and De Bakey, M. E.: The Use of Hypothermia in the Prevention of Paraplegia Following Temporary Aortic Occlusion: Experimental Observations , Surgery 36:33, 1954. 3. De Bakey, M. E., in discussion on King, H., and Shumacker, H. B.: Mechanical By-Pass During Thoracic Aortic Cross-Clamping , J. Thoracic Surg. 34:485-499, 1957, p. 498.

Journal

A.M.A. Archives SurgeryAmerican Medical Association

Published: Apr 1, 1959

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