Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Intestinal Injuries Following Irradiation of Pelvic Viscera for Malignancy

Intestinal Injuries Following Irradiation of Pelvic Viscera for Malignancy Abstract The occurrence of irradiation lesions in the intestinal tract subsequent to the treatment of malignancies is well known. In a survey of intestinal obstruction at the University of Illinois Hospitals for the period between Jan. 1, 1947, and December, 1955, twelve cases of intestinal injury secondary to pelvic irradiation for malignant disease of the reproductive organs were encountered and are the subject of this report. All were females and all showed, among other manifestations, partial or complete obstruction of the bowel. There were four deaths, a mortality rate of 33%. Our purpose here is to review these cases, point out the diagnostic features of benign irradiation stricture, and discuss methods of treatment. Many reports have appeared in the literature regarding the destructive effects of pelvic References 1. References 17 and 24. 2. Aldridge, A. H.: Intestinal Injuries Resulting from Irradiation Treatment of Uterine Carcinoma , Am. J. Obst. & Gynec. 44:833, 1942. 3. Bacon, H.: Radiation Proctitis , Radiology 29:574, 1937. 4. Black, W. A., and Waugh, J. M.: Resection for Strictures of the Recto-Sigmoid Following Radium Treatment for Carcinoma of Cervix , Proc. Staff Meet. Mayo Clin. 20:87 ( (March 2) ) 1945. 5. Buie, L. A., and Malmgren, G. E.: Factitial Proctitis: Justifiable Lesion Found in Patients Following Irradiation , Internat. Clin. 3:68, 1930. 6. Cathie, I. A.: Ulceration of Small Intestines Following Irradiation of the Pelvis , Am. J. Roentgenol. 39:895, 1938. 7. Cutler, M.: Complications of Radio-Therapy in Cancer of Cervix , Surg. Gynec. & Obst. 74:867, 1942. 8. Desjardins, A. U.: Action of Roentgen Rays and Radium on the Gastrointestinal Tract , Am. J. Roentgenol. 26:145, 1931. 9. Feder, I. A., and Leichtling, M.: Factitial Sigmoiditis: Report of a Case , Rev. Gastroenterol. 19:902, 1952. 10. Frank, R. C., and Pohle, E. A.: Late Radiation Reaction in the Small Intestine Manifest 8 Years After Therapy , Ann. Surg. 133:104, 1951. 11. Gardner, C. E., and Anlyan, W. G.: Radiation Injury to the Small Intestine , Surgery 31:746, 1952. 12. Hesly, W. P., and Frazell, E.: Methods and Results of Treatment in Carcinoma of the Cervix at Memorial Hospital , Am. J. Obst. & Gynec. 34:593, 1937. 13. Ferguson, C. H.: Secondary Effects of Radiation upon the Rectum Following Treatment of Extra Rectal Pelvic Lesions , Am. J. Digest. Dis. 4:712, 1938. 14. Jones, T. E.: Benign Stricture of Intestine Due to Irradiation , S. Clin. North America 19:1185, 1939. 15. Jones, T. E.: Radiation Strictures of Bowel , Am. J. Obst. & Gynec. 29:309, 1935. 16. Maas, J. M.: Intestinal Changes Secondary to Irradiation of Pelvic Malignancies , Am. J. Obst. & Gynec. 56:249, 1948. 17. Mulligan, R. M.: Lesions Produced in Gastrointestinal Tract by Irradiation: General Review and Case Report , Am. J. Path. 18:515, 1942. 18. Pemberton, F.: Complications of Radiation Treatment in Gynecology , Am. J. Obst. & Gynec. 24:552, 1932. 19. Handle, L. M., and Buie, L.: Factitial Proctitis , Am. J. Obst. & Gynec. 45:505, 1943. 20. Requarth, W., and Roberts, S.: Intestinal Obstruction, to be published. 21. Wiley, H. M., and Sugarbaker, E. D.: Roentgenotherapeutic Changes in the Small Intestine: Surgical Aspects , Cancer 3:629, 1950. 22. Warren, S., and Friedmann, N.: Pathology and Pathologic Diagnosis of Radiation Lesions in Gastrointestinal Tract , Am. J. Path. 18:499, 1942. 23. Waterman, G. W., and Tracy, E. M.: Complications Following the Use of Low Intensity, Long Radium Element Needles in the Treatment of Cancer of the Cervix Uteri , Am. J. Roentgenol. 60:788, 1948. 24. White, W. C.: Acute Intestinal Obstruction Following Treatment of Carcinoma of Cervix Uteri , Am. J. Surg. 105:292, 1937. 25. White, W. C., and Finn, F. W.: Late Complications Following Irradiation of Pelvic Viscera , Am. J. Obst. & Gynec. 62:65, 1951. 26. Wigby, P. E.: Post-Irradiation Stricture of Rectum and Sigmoid Following Treatment for Cervical Cancer , Am. J. Roentgenol. 49:307, 1943. 27. Todd, T. F.: Rectal Ulceration Following Irradiation Treatment of Carcinoma Cervix Uteri: Pseudocarcinoma of Rectum , Surg. Gynec. & Obst. 67:617, 1938. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives Surgery American Medical Association

Intestinal Injuries Following Irradiation of Pelvic Viscera for Malignancy

REQUARTH, WILLIAM; ROBERTS, STUART
A.M.A. Archives Surgery , Volume 73 (4) – Oct 1, 1956
Download PDF
7 pages

Loading next page...
 
/lp/american-medical-association/intestinal-injuries-following-irradiation-of-pelvic-viscera-for-PbhDdW78YH

References (31)

Publisher
American Medical Association
Copyright
Copyright © 1956 American Medical Association. All Rights Reserved.
ISSN
0096-6908
DOI
10.1001/archsurg.1956.01280040138016
Publisher site
See Article on Publisher Site

Abstract

Abstract The occurrence of irradiation lesions in the intestinal tract subsequent to the treatment of malignancies is well known. In a survey of intestinal obstruction at the University of Illinois Hospitals for the period between Jan. 1, 1947, and December, 1955, twelve cases of intestinal injury secondary to pelvic irradiation for malignant disease of the reproductive organs were encountered and are the subject of this report. All were females and all showed, among other manifestations, partial or complete obstruction of the bowel. There were four deaths, a mortality rate of 33%. Our purpose here is to review these cases, point out the diagnostic features of benign irradiation stricture, and discuss methods of treatment. Many reports have appeared in the literature regarding the destructive effects of pelvic References 1. References 17 and 24. 2. Aldridge, A. H.: Intestinal Injuries Resulting from Irradiation Treatment of Uterine Carcinoma , Am. J. Obst. & Gynec. 44:833, 1942. 3. Bacon, H.: Radiation Proctitis , Radiology 29:574, 1937. 4. Black, W. A., and Waugh, J. M.: Resection for Strictures of the Recto-Sigmoid Following Radium Treatment for Carcinoma of Cervix , Proc. Staff Meet. Mayo Clin. 20:87 ( (March 2) ) 1945. 5. Buie, L. A., and Malmgren, G. E.: Factitial Proctitis: Justifiable Lesion Found in Patients Following Irradiation , Internat. Clin. 3:68, 1930. 6. Cathie, I. A.: Ulceration of Small Intestines Following Irradiation of the Pelvis , Am. J. Roentgenol. 39:895, 1938. 7. Cutler, M.: Complications of Radio-Therapy in Cancer of Cervix , Surg. Gynec. & Obst. 74:867, 1942. 8. Desjardins, A. U.: Action of Roentgen Rays and Radium on the Gastrointestinal Tract , Am. J. Roentgenol. 26:145, 1931. 9. Feder, I. A., and Leichtling, M.: Factitial Sigmoiditis: Report of a Case , Rev. Gastroenterol. 19:902, 1952. 10. Frank, R. C., and Pohle, E. A.: Late Radiation Reaction in the Small Intestine Manifest 8 Years After Therapy , Ann. Surg. 133:104, 1951. 11. Gardner, C. E., and Anlyan, W. G.: Radiation Injury to the Small Intestine , Surgery 31:746, 1952. 12. Hesly, W. P., and Frazell, E.: Methods and Results of Treatment in Carcinoma of the Cervix at Memorial Hospital , Am. J. Obst. & Gynec. 34:593, 1937. 13. Ferguson, C. H.: Secondary Effects of Radiation upon the Rectum Following Treatment of Extra Rectal Pelvic Lesions , Am. J. Digest. Dis. 4:712, 1938. 14. Jones, T. E.: Benign Stricture of Intestine Due to Irradiation , S. Clin. North America 19:1185, 1939. 15. Jones, T. E.: Radiation Strictures of Bowel , Am. J. Obst. & Gynec. 29:309, 1935. 16. Maas, J. M.: Intestinal Changes Secondary to Irradiation of Pelvic Malignancies , Am. J. Obst. & Gynec. 56:249, 1948. 17. Mulligan, R. M.: Lesions Produced in Gastrointestinal Tract by Irradiation: General Review and Case Report , Am. J. Path. 18:515, 1942. 18. Pemberton, F.: Complications of Radiation Treatment in Gynecology , Am. J. Obst. & Gynec. 24:552, 1932. 19. Handle, L. M., and Buie, L.: Factitial Proctitis , Am. J. Obst. & Gynec. 45:505, 1943. 20. Requarth, W., and Roberts, S.: Intestinal Obstruction, to be published. 21. Wiley, H. M., and Sugarbaker, E. D.: Roentgenotherapeutic Changes in the Small Intestine: Surgical Aspects , Cancer 3:629, 1950. 22. Warren, S., and Friedmann, N.: Pathology and Pathologic Diagnosis of Radiation Lesions in Gastrointestinal Tract , Am. J. Path. 18:499, 1942. 23. Waterman, G. W., and Tracy, E. M.: Complications Following the Use of Low Intensity, Long Radium Element Needles in the Treatment of Cancer of the Cervix Uteri , Am. J. Roentgenol. 60:788, 1948. 24. White, W. C.: Acute Intestinal Obstruction Following Treatment of Carcinoma of Cervix Uteri , Am. J. Surg. 105:292, 1937. 25. White, W. C., and Finn, F. W.: Late Complications Following Irradiation of Pelvic Viscera , Am. J. Obst. & Gynec. 62:65, 1951. 26. Wigby, P. E.: Post-Irradiation Stricture of Rectum and Sigmoid Following Treatment for Cervical Cancer , Am. J. Roentgenol. 49:307, 1943. 27. Todd, T. F.: Rectal Ulceration Following Irradiation Treatment of Carcinoma Cervix Uteri: Pseudocarcinoma of Rectum , Surg. Gynec. & Obst. 67:617, 1938.

Journal

A.M.A. Archives Surgery – American Medical Association

Published: Oct 1, 1956

There are no references for this article.