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ADENOCARCINOMA ARISING IN DIVERTICULUM OF URINARY BLADDER

ADENOCARCINOMA ARISING IN DIVERTICULUM OF URINARY BLADDER Abstract CARCINOMA within a diverticulum of the urinary bladder is rare. In culling the world literature, 200 cases have been found reported. Of this group, only two were adenocarcinoma.* This incidence corresponds to that of neoplasms of glandular structure in the bladder in general. Glandular elements are usually absent in the normal bladder except for those found at the neck and in the trigone, arising in the subtrigonal and subcervical glands of Albarran.3 Many theories have been advanced to explain the finding of glandular tissue in an organ that is almost exclusively lined with transitional epithelium. Urachal remnants—the fetal allantoid duct—may proliferate and undergo malignant change. The embryonic cloaca-like origin of the bladder may be important in the formation of mucus-producing glands. Glandular elements appear in the bladder through a process of metaplasia as a result of chronic infection or chronic irritation, usually secondary to calculi or prostatic obstruction. REPORT References 1. References 1 and 2. 2. Abeshouse, B. S., and Goldstein, A. E.: Primary Carcinoma in a Diverticulum of the Bladder , J. Urol. 49:534. 1943. 3. Boylan, R. N.; Greene, L., and McDonald, J. R.: Epithelial Neoplasms Arising in Diverticula of the Urinary Bladder , J. Urol. 65:1041, 1951. 4. Albarran, J.: Les tumeurs de la vessie , Paris, G. Steinheil, 1892, pp. 78-79. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives Surgery American Medical Association

ADENOCARCINOMA ARISING IN DIVERTICULUM OF URINARY BLADDER

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1954 American Medical Association. All Rights Reserved.
ISSN
0096-6908
DOI
10.1001/archsurg.1954.01270050156027
Publisher site
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Abstract

Abstract CARCINOMA within a diverticulum of the urinary bladder is rare. In culling the world literature, 200 cases have been found reported. Of this group, only two were adenocarcinoma.* This incidence corresponds to that of neoplasms of glandular structure in the bladder in general. Glandular elements are usually absent in the normal bladder except for those found at the neck and in the trigone, arising in the subtrigonal and subcervical glands of Albarran.3 Many theories have been advanced to explain the finding of glandular tissue in an organ that is almost exclusively lined with transitional epithelium. Urachal remnants—the fetal allantoid duct—may proliferate and undergo malignant change. The embryonic cloaca-like origin of the bladder may be important in the formation of mucus-producing glands. Glandular elements appear in the bladder through a process of metaplasia as a result of chronic infection or chronic irritation, usually secondary to calculi or prostatic obstruction. REPORT References 1. References 1 and 2. 2. Abeshouse, B. S., and Goldstein, A. E.: Primary Carcinoma in a Diverticulum of the Bladder , J. Urol. 49:534. 1943. 3. Boylan, R. N.; Greene, L., and McDonald, J. R.: Epithelial Neoplasms Arising in Diverticula of the Urinary Bladder , J. Urol. 65:1041, 1951. 4. Albarran, J.: Les tumeurs de la vessie , Paris, G. Steinheil, 1892, pp. 78-79.

Journal

A.M.A. Archives Surgery – American Medical Association

Published: Nov 1, 1954

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