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EXPERIMENTAL ESOPHAGEAL AND PHARYNGOCERVICAL FISTULA

EXPERIMENTAL ESOPHAGEAL AND PHARYNGOCERVICAL FISTULA Abstract ESOPHAGEAL fistulas in the laboratory animal have been utilized for a variety of experimental purposes. Pavlov and Schumova-Simanovskaia1 used dogs with cervical and gastric fistulas in their studies on the relationship of the vagus nerves to gastric secretion. Pavlov2 states that neck infection in the dog is serious and often fatal. In 1929 Saint and Mann3 cited the appalling mortality associated with experimental surgery of the esophagus and called attention to the factors of poor blood supply and lack of a true serosa. Saint4 later stressed the risk of fatal infection of the pleura and the cellular tissues of the neck. Allen5 mentions the frequency of mediastinitis during the course of experimental surgery when the lumen of the esophagus is opened. After the clinical experiences of Sturgeon6 and Lahey7 with esophageal diverticulas, both Allen5 and Markowitz8 advocated the use of two References 1. Pavlov, I. P.: The Work of the Digestive Glands , ed. 2, translated by W. H. Thompson, London, Charles Griffin and Co., 1910. 2. Pavlov, I. P.: Die operative Methodik der Studiums der Verdauungsdrüsen , Handb. physiol. Method. 2:150, 1908. 3. Saint, J. H., and Mann, F. C.: Experimental Surgery of the Esophagus , Arch. Surg. 18:2324 ( (June) ) 1929.Crossref 4. Saint, J. H.: Surgery of the Esophagus , Arch. Surg. 19:53 ( (July) ) 1929.Crossref 5. Allen, D. S.: Further Experimental Reconstruction of the Esophagus with Autogenous Fascia Lata Transplants , Arch. Surg. 10:374 ( (Jan.) ) 1925.Crossref 6. Sturgeon, C. T.: Esophageal Diverticulum , J. A. M. A. 92:379 ( (Feb. 2) ) 1929.Crossref 7. Lahey, F. H.: The Surgical Management of Pharyngo-Oesophageal Diverticulum , Surg., Gynec. & Obst. 51:227, 1930. 8. Markowitz, J.: Experimental Surgery , ed. 2, Baltimore, Williams & Wilkins Company, 1949. 9. Andrus, W. DeW., and Donnelly, J. L.: Effects of Certain Operations on the Esophagus of the Dog , Arch. Surg. 20:1 ( (Jan.) ) 1930. 10. Wilder, T. S., and Stokes, J. S.: Esophageal Fistula in the Experimental Animal , Arch. Surg. 23:111 ( (July) ) 1931. 11. Dragstedt, C. A., and Mullinex, R. B.: Experimental Esophageal Obstruction , Arch. Surg. 24:152 ( (Jan.) ) 1932 12. Experimental Esophageal Fistula , J. Lab. & Clin. Med. 16:591, 1931. 13. Howe, C. W.; Porell, W. J., and Ware, P. F.: Assessment of Gastric Secretory Responses in Relation to Peptic Ulcer, Arch. Surg., to be published. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives Surgery American Medical Association

EXPERIMENTAL ESOPHAGEAL AND PHARYNGOCERVICAL FISTULA

WARE, PAUL F.; HOWE, CHESTER W.
A.M.A. Archives Surgery , Volume 63 (2) – Aug 1, 1951
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References (12)

Publisher
American Medical Association
Copyright
Copyright © 1951 American Medical Association. All Rights Reserved.
ISSN
0096-6908
DOI
10.1001/archsurg.1951.01250040233012
Publisher site
See Article on Publisher Site

Abstract

Abstract ESOPHAGEAL fistulas in the laboratory animal have been utilized for a variety of experimental purposes. Pavlov and Schumova-Simanovskaia1 used dogs with cervical and gastric fistulas in their studies on the relationship of the vagus nerves to gastric secretion. Pavlov2 states that neck infection in the dog is serious and often fatal. In 1929 Saint and Mann3 cited the appalling mortality associated with experimental surgery of the esophagus and called attention to the factors of poor blood supply and lack of a true serosa. Saint4 later stressed the risk of fatal infection of the pleura and the cellular tissues of the neck. Allen5 mentions the frequency of mediastinitis during the course of experimental surgery when the lumen of the esophagus is opened. After the clinical experiences of Sturgeon6 and Lahey7 with esophageal diverticulas, both Allen5 and Markowitz8 advocated the use of two References 1. Pavlov, I. P.: The Work of the Digestive Glands , ed. 2, translated by W. H. Thompson, London, Charles Griffin and Co., 1910. 2. Pavlov, I. P.: Die operative Methodik der Studiums der Verdauungsdrüsen , Handb. physiol. Method. 2:150, 1908. 3. Saint, J. H., and Mann, F. C.: Experimental Surgery of the Esophagus , Arch. Surg. 18:2324 ( (June) ) 1929.Crossref 4. Saint, J. H.: Surgery of the Esophagus , Arch. Surg. 19:53 ( (July) ) 1929.Crossref 5. Allen, D. S.: Further Experimental Reconstruction of the Esophagus with Autogenous Fascia Lata Transplants , Arch. Surg. 10:374 ( (Jan.) ) 1925.Crossref 6. Sturgeon, C. T.: Esophageal Diverticulum , J. A. M. A. 92:379 ( (Feb. 2) ) 1929.Crossref 7. Lahey, F. H.: The Surgical Management of Pharyngo-Oesophageal Diverticulum , Surg., Gynec. & Obst. 51:227, 1930. 8. Markowitz, J.: Experimental Surgery , ed. 2, Baltimore, Williams & Wilkins Company, 1949. 9. Andrus, W. DeW., and Donnelly, J. L.: Effects of Certain Operations on the Esophagus of the Dog , Arch. Surg. 20:1 ( (Jan.) ) 1930. 10. Wilder, T. S., and Stokes, J. S.: Esophageal Fistula in the Experimental Animal , Arch. Surg. 23:111 ( (July) ) 1931. 11. Dragstedt, C. A., and Mullinex, R. B.: Experimental Esophageal Obstruction , Arch. Surg. 24:152 ( (Jan.) ) 1932 12. Experimental Esophageal Fistula , J. Lab. & Clin. Med. 16:591, 1931. 13. Howe, C. W.; Porell, W. J., and Ware, P. F.: Assessment of Gastric Secretory Responses in Relation to Peptic Ulcer, Arch. Surg., to be published.

Journal

A.M.A. Archives Surgery – American Medical Association

Published: Aug 1, 1951

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