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THE FACTOR OF SPASM IN THE ETIOLOGY OF PEPTIC ULCERS

THE FACTOR OF SPASM IN THE ETIOLOGY OF PEPTIC ULCERS Abstract Exalto1 was the first investigator to develop a technic which regularly produced chronic ulcerations of the jejunum. He severed the stomach immediately above the pyloric valve according to the method of von Eiselsberg. The distal and proximal ends of the stomach were closed. The jejunum was severed distal to the duodenojejunal flexure, and both ends were closed. The distal jejunum was anastomosed to the stomach near its proximal closed end. The duodenum was anastomosed into the jejunum 20 cm. distal to the gastrojejunal anastomosis, according to the method of Roux, or into the colon (fig. 1). Exalto therefore deserves the credit for the originality in implanting the duodenum into the colon and thus completely diverting the alkaline duodenal contents from the gastrojejunal anastomosis. Exalto performed a typical gastrojejunal anastomosis in seven dogs according to the method of von Eiselsberg without the short-circuiting operation of Roux. He failed to obtain References 1. Exalto, J.: Ulcus jejuni nach Gastroenterostomie , Mitt. a. d. Grenzgeb. d. Med. u. Chir. 23:13, 1911. 2. McCann, J. C.: Experimental Peptic Ulcer , Arch. Surg. 19:600 ( (Oct.) ) 1929.Crossref 3. Matthews, W. B., and Dragstedt, L. R.: The Etiology of Gastric and Duodenal Ulcers , Surg., Gynec. & Obst. 55:265 ( (Sept.) ) 1932. 4. Mann, F. C., and Williamson, C. S.: The Experimental Production of Peptic Ulcer , Ann. Surg. 77:409 ( (April) ) 1923. 5. Ivy, A. C.: Factors Concerned in Determining the Chronicity of Ulcers in the Stomach and the Upper Intestine: Susceptibility of Jejunum to Ulcer Formation; Effect of Diet on Healing of Acute Gastric Ulcers , Am. J. Surg. 11:531, 1931. 6. Steinberg, M. E., and Proffitt, J. C.: The Etiology of Postoperative Peptic Ulcers , Arch. Surg. 25:819 ( (Nov.) ) 1932. 7. Winkelbauer, A.: Studien ueber die Verhütung des Ulcus pepticum postoperativum im Experiment , Arch. f. klin. Chir. 143:649, 1926. 8. Steinberg, M. E.: The Exclusion Operation for Duodenal Ulcers , Am. J. Surg. 23:137 ( (Jan.) ) 1934. 9. Boldyreff, W.: The Self-Regulation of the Acidity of the Gastric Juice , Quart. J. Exper. Physiol. 8:1, 1915. 10. Burget, G. E., and Steinberg, M. E.: The Regurgitation of Intestinal Contents in Normal Dogs and Dogs with Posterior Gastro-Enterostomy , Am. J. Physiol. 60:308 ( (April) ) 1922. 11. Steinberg, M. E.; Brougher, J. C., and Vidgoff, I. J.: Changes in the Chemistry of the Contents of the Stomach Following Gastric Operations , Arch. Surg. 15:749 ( (Nov.) ) 1927. 12. Elman, Robert: Acidity in Duodenal Ulcer and Pyloric Obstruction , Surg., Gynec. & Obst. 49:34, 1929. 13. Cannon, W. B.: The Mechanical Factors of Digestion , London, Edward Arnold & Co., 1911. 14. Dragstedt, L. R., and Vaughn, A. M.: Gastric Ulcer Studies; the Resistance of Various Tissues to Gastric Digestion , Arch. Surg. 8:791 ( (May) ) 1924. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

THE FACTOR OF SPASM IN THE ETIOLOGY OF PEPTIC ULCERS

STEINBERG, M. E.; STARR, PAUL H.
Archives of Surgery , Volume 29 (6) – Dec 1, 1934
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References (16)

Publisher
American Medical Association
Copyright
Copyright © 1934 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1934.01180060002001
Publisher site
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Abstract

Abstract Exalto1 was the first investigator to develop a technic which regularly produced chronic ulcerations of the jejunum. He severed the stomach immediately above the pyloric valve according to the method of von Eiselsberg. The distal and proximal ends of the stomach were closed. The jejunum was severed distal to the duodenojejunal flexure, and both ends were closed. The distal jejunum was anastomosed to the stomach near its proximal closed end. The duodenum was anastomosed into the jejunum 20 cm. distal to the gastrojejunal anastomosis, according to the method of Roux, or into the colon (fig. 1). Exalto therefore deserves the credit for the originality in implanting the duodenum into the colon and thus completely diverting the alkaline duodenal contents from the gastrojejunal anastomosis. Exalto performed a typical gastrojejunal anastomosis in seven dogs according to the method of von Eiselsberg without the short-circuiting operation of Roux. He failed to obtain References 1. Exalto, J.: Ulcus jejuni nach Gastroenterostomie , Mitt. a. d. Grenzgeb. d. Med. u. Chir. 23:13, 1911. 2. McCann, J. C.: Experimental Peptic Ulcer , Arch. Surg. 19:600 ( (Oct.) ) 1929.Crossref 3. Matthews, W. B., and Dragstedt, L. R.: The Etiology of Gastric and Duodenal Ulcers , Surg., Gynec. & Obst. 55:265 ( (Sept.) ) 1932. 4. Mann, F. C., and Williamson, C. S.: The Experimental Production of Peptic Ulcer , Ann. Surg. 77:409 ( (April) ) 1923. 5. Ivy, A. C.: Factors Concerned in Determining the Chronicity of Ulcers in the Stomach and the Upper Intestine: Susceptibility of Jejunum to Ulcer Formation; Effect of Diet on Healing of Acute Gastric Ulcers , Am. J. Surg. 11:531, 1931. 6. Steinberg, M. E., and Proffitt, J. C.: The Etiology of Postoperative Peptic Ulcers , Arch. Surg. 25:819 ( (Nov.) ) 1932. 7. Winkelbauer, A.: Studien ueber die Verhütung des Ulcus pepticum postoperativum im Experiment , Arch. f. klin. Chir. 143:649, 1926. 8. Steinberg, M. E.: The Exclusion Operation for Duodenal Ulcers , Am. J. Surg. 23:137 ( (Jan.) ) 1934. 9. Boldyreff, W.: The Self-Regulation of the Acidity of the Gastric Juice , Quart. J. Exper. Physiol. 8:1, 1915. 10. Burget, G. E., and Steinberg, M. E.: The Regurgitation of Intestinal Contents in Normal Dogs and Dogs with Posterior Gastro-Enterostomy , Am. J. Physiol. 60:308 ( (April) ) 1922. 11. Steinberg, M. E.; Brougher, J. C., and Vidgoff, I. J.: Changes in the Chemistry of the Contents of the Stomach Following Gastric Operations , Arch. Surg. 15:749 ( (Nov.) ) 1927. 12. Elman, Robert: Acidity in Duodenal Ulcer and Pyloric Obstruction , Surg., Gynec. & Obst. 49:34, 1929. 13. Cannon, W. B.: The Mechanical Factors of Digestion , London, Edward Arnold & Co., 1911. 14. Dragstedt, L. R., and Vaughn, A. M.: Gastric Ulcer Studies; the Resistance of Various Tissues to Gastric Digestion , Arch. Surg. 8:791 ( (May) ) 1924.

Journal

Archives of Surgery – American Medical Association

Published: Dec 1, 1934

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