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THE BREAKING STRENGTH OF HEALING FRACTURED FIBULAE OF RATS: IV. OBSERVATIONS ON A HIGH CARBOHYDRATE DIET

THE BREAKING STRENGTH OF HEALING FRACTURED FIBULAE OF RATS: IV. OBSERVATIONS ON A HIGH... Abstract In previous papers we have considered the effect of a standard diet1 and of a high fat diet2 on the breaking strength of healing fractured fibulae in albino rats. In our present paper we shall report the results of a study of the influence exerted on the breaking strength of similar fractures by a high carbohydrate diet. The absorption of calcium and phosphorus from the gastro-intestinal tract has been shown to be favored by acidic intestinal contents.3 Consequently the foods that produce such contents are advantageous in the assimilation of these salts. Lactose, for one, establishes acid-producing flora in the intestine, while corn starch changes the reaction of the tract but slightly.4 In agreement with the changes in the hydrogen ion concentration produced by these two carbohydrates, it has been demonstrated experimentally that lactose increases the absorption of calcium and phosphorus, while starch diets are followed References 1. McKeown, R. M.; Lindsay, M. K.; Harvey, S. C., and Howes, E. L.: The Breaking Strength of Healing Fractured Fibulae of Rats: II. Observations on a Standard Diet , Arch. Surg. 24:458 ( (March) ) 1932.Crossref 2. McKeown, R. M.; Lindsay, M. K.; Harvey, S. C., and Lumsden, R. W.: The Breaking Strength of Healing Fractured Fibulae of Rats: III. Observations on a High Fat Diet , Arch. Surg. 25:467 ( (Sept.) ) 1932.Crossref 3. Orr; W. J.; Holt, L. E., Jr.; Wilkins, L., and Boone, F. H.: The Relation of Calcium and Phosphorus in the Diet to the Absorption of These Elements from the Intestine , Am. J. Dis. Child. 28:574 ( (Nov.) ) 1924. 4. Irving, L., and Ferguson, J.: Proc. Soc. Exper. Biol. & Med. 22:527, 1925. 5. Mitchell, H. S.: Am. J. Physiol. 79:537, 1927. 6. Bergeim, O.: J. Biol. Chem. 70:35, 1926. 7. Block, C. E.: Brit. M. J. 1:293, 1921. 8. Bolliger, A., and Hartman, F. W.: J. Biol. Chem. 64:91, 1925. 9. Harrop, G. A., and Benedict, E. M.: J. Biochem. 59:683, 1924. 10. Lambie, C. G., and Redhead, F. A.: Biochem. J. 21:549, 1927. 11. Martland, M., and Robison, R.: Biochem. J. 23:237, 1929. 12. Kay, H. D.: Biochem. J. 20:798, 1926. 13. Goodwin, H. W., and Robison, R.: Biochem. J. 18:1161, 1924. 14. Hoag, J. R., and Palmer, L. S.: J. Biol. Chem. 76:367, 1928. 15. Bethke, R. M.; Steenbock, H., and Nelson, M.: J. Biol. Chem. 58:71, 1923. 16. Cori, C. F., and Cori, G. T.: J. Biol. Chem. 79:321, 1928. 17. Reed, C. I.: Am. J. Physiol. 89:230, 1929. 18. McKeown, Lindsay, Harvey and Howes (footnote 1). McKeown, Lindsay, Harvey and Lumsden (footnote 2). 19. Moise, T. S., and Smith, A. H.: J. Exper. Med. 40:13, 1924. 20. Osborne, T. B., and Mendel, L. B.: J. Biol. Chem. 37:557, 1919. 21. Smith, A. H., and Carey, E.: J. Biol. Chem. 53:425, 1923. 22. Kay, H. D.: J. Biol. Chem. 99:249, 1930. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

THE BREAKING STRENGTH OF HEALING FRACTURED FIBULAE OF RATS: IV. OBSERVATIONS ON A HIGH CARBOHYDRATE DIET

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References (17)

Publisher
American Medical Association
Copyright
Copyright © 1932 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1932.01160220110004
Publisher site
See Article on Publisher Site

Abstract

Abstract In previous papers we have considered the effect of a standard diet1 and of a high fat diet2 on the breaking strength of healing fractured fibulae in albino rats. In our present paper we shall report the results of a study of the influence exerted on the breaking strength of similar fractures by a high carbohydrate diet. The absorption of calcium and phosphorus from the gastro-intestinal tract has been shown to be favored by acidic intestinal contents.3 Consequently the foods that produce such contents are advantageous in the assimilation of these salts. Lactose, for one, establishes acid-producing flora in the intestine, while corn starch changes the reaction of the tract but slightly.4 In agreement with the changes in the hydrogen ion concentration produced by these two carbohydrates, it has been demonstrated experimentally that lactose increases the absorption of calcium and phosphorus, while starch diets are followed References 1. McKeown, R. M.; Lindsay, M. K.; Harvey, S. C., and Howes, E. L.: The Breaking Strength of Healing Fractured Fibulae of Rats: II. Observations on a Standard Diet , Arch. Surg. 24:458 ( (March) ) 1932.Crossref 2. McKeown, R. M.; Lindsay, M. K.; Harvey, S. C., and Lumsden, R. W.: The Breaking Strength of Healing Fractured Fibulae of Rats: III. Observations on a High Fat Diet , Arch. Surg. 25:467 ( (Sept.) ) 1932.Crossref 3. Orr; W. J.; Holt, L. E., Jr.; Wilkins, L., and Boone, F. H.: The Relation of Calcium and Phosphorus in the Diet to the Absorption of These Elements from the Intestine , Am. J. Dis. Child. 28:574 ( (Nov.) ) 1924. 4. Irving, L., and Ferguson, J.: Proc. Soc. Exper. Biol. & Med. 22:527, 1925. 5. Mitchell, H. S.: Am. J. Physiol. 79:537, 1927. 6. Bergeim, O.: J. Biol. Chem. 70:35, 1926. 7. Block, C. E.: Brit. M. J. 1:293, 1921. 8. Bolliger, A., and Hartman, F. W.: J. Biol. Chem. 64:91, 1925. 9. Harrop, G. A., and Benedict, E. M.: J. Biochem. 59:683, 1924. 10. Lambie, C. G., and Redhead, F. A.: Biochem. J. 21:549, 1927. 11. Martland, M., and Robison, R.: Biochem. J. 23:237, 1929. 12. Kay, H. D.: Biochem. J. 20:798, 1926. 13. Goodwin, H. W., and Robison, R.: Biochem. J. 18:1161, 1924. 14. Hoag, J. R., and Palmer, L. S.: J. Biol. Chem. 76:367, 1928. 15. Bethke, R. M.; Steenbock, H., and Nelson, M.: J. Biol. Chem. 58:71, 1923. 16. Cori, C. F., and Cori, G. T.: J. Biol. Chem. 79:321, 1928. 17. Reed, C. I.: Am. J. Physiol. 89:230, 1929. 18. McKeown, Lindsay, Harvey and Howes (footnote 1). McKeown, Lindsay, Harvey and Lumsden (footnote 2). 19. Moise, T. S., and Smith, A. H.: J. Exper. Med. 40:13, 1924. 20. Osborne, T. B., and Mendel, L. B.: J. Biol. Chem. 37:557, 1919. 21. Smith, A. H., and Carey, E.: J. Biol. Chem. 53:425, 1923. 22. Kay, H. D.: J. Biol. Chem. 99:249, 1930.

Journal

Archives of SurgeryAmerican Medical Association

Published: Oct 1, 1932

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