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(1914)
A Study of the Pathology of the Thyroids from Cases of Toxic-Non-Exophthalmic GoiterJournal-Lancet, 34
H. S. Plummer (1921)
Functions of the Normal and Abnormal Thyroid Gland, 3
A. S. Giordano (1923)
Histological Study of the Effect of Ligation of the Thyroid Vessels in Exopthalmic GoiterSurg. Gynec. Obst., 36
W. S. Halsted (1896)
An Experimental Study of the Thyroid Gland of Dogs with Special Consideration of Hypertrophy of this GlandRep. Johns Hopkins Hosp., 1
David Marine , C. H. and Lenhart (1909)
The Colloid Glands (Goitres), Their Etiology and Physiological SignificanceBull. Johns Hopkins Hosp., 20
(1913)
Notes on the Pathology of Simple and Exophthalmic GoiterM. Rec., 84
Leo Loeb , E. E. and Kaplan (1924)
Studies of Compensatory Hypertrophy of the Thyroid Gland: VI. The Effect of Feeding Anterior Lobe of the Pituitary Gland on the Hypertrophy of the Thyroid Gland in the Guinea-pigJ. M. Research, 44
H. Plummer (1913)
THE CLINICAL AND PATHOLOGICAL RELATIONSHIP OF SIMPLE AND EXOPHTHALMIC GOITERThe American Journal of the Medical Sciences, 146
(1887)
Function of the Thyroid GlandThe Southern Medical Record, 17
Gottfried Hämig (1897)
Anatomische Untersuchungen �ber Morbus BasedowiiArch. f. klin. Chir., 55
(1911)
Pathological Anatomy of Exophthalmic GoiterArch. Int. Med., 8
W. F. Rienhoff (1925)
The Historical Changes Brought About in Cases of Exophthalmic Goiter by the Administration of IodineBull. Johns Hopkins Hosp., 37
L. Wilson (1914)
A STUDY OP THE PATHOLOGY OF THE THYROIDS FROM CASES OF TOXIC NON‐EXOPHTHALMIC GOITERThe American Journal of the Medical Sciences, 147
David Marine (1907)
On the Occurrence and Physiological Nature of Glandular Hyperplasia of the Thyroid (Dog and Sheep) Together with Remarks on Important Clinical Human ProblemsBull. Johns Hopkins Hosp., 18
Victor Horsley (1886)
The Pathology of the Thyroid Gland, Brown LecturesLancet, 2
H. S. Plummer (1925)
The Function of the Thyroid GlandCollected Papers of The Mayo Clinic and The Mayo Foundation, 17
Leo Loeb (1919-1920)
Studies on Compensatory Hypertrophy of Thyroid Gland: IV. The Influence of Iodine on Hypertrophy of the Thyroid GlandJ. M. Research, 41
H. S. Plummer (1924)
The Value of Iodin in Exophthalmic GoiterJ. Iowa M. Soc., 14
David Marine , W. W. and Williams (1908)
The Relation of Iodine to the Structure of the Thyroid GlandArch. Int. Med., 1
E. C. Kendall (1915)
The Isolation in Crystalline Form of the Compound Containing Iodin which Occurs in the Thyroid: Its Clinical Nature and Physiological ActivityTr. A. Am. Phys., 30
Wagener (1884)
Ueber die Folgen der Extirpation der Schilddr�se nach Versuchen an ThierenWien med. Bl.
(1913)
The Pathology of the Thyroid Gland in Exophthalmic GoiterAm. J. M. Sc., 146
W. S. Halsted (1913)
Factors Which May Be Concerned in Causing Hypertrophy of the Thyroid Gland and the Effect of Excision of this Organ upon Other of the Ductless GlandsTr. A. Am. Phys., 28
R. B. Cattell (1925)
The Pathology of Exophthalmic Goiter. A Histological and Chemical Study of the Change Following Administration of Iodine (Lugol's Solution)Boston M. & S. J., 192
Loeb (1921)
Studies on Compensatory Hypertrophy of the Thyroid Gland: V. The Effect of the Administration of Thyroid, Thymus Gland and Tethelin and of a Meat Diet on the Hypertrophy of the Thyroid Gland in Guinea-PigsJ. M. Research, 42
D. Marine, C. Lenhart (1911)
THE PATHOLOGICAL ANATOMY OF THE HUMAN THYROID GLANDJAMA Internal Medicine
L. B. Wilson (1913)
The Relationship of the Clinical and Pathologic Aspects of Exophthalmic GoiterNorthwest. Med., 5
E. Kendall (1915)
The Isolation in Crystalline Form of the Compound Containing Iodin, Which Occurs in the Thyroid: Its Chemical Nature and Physiologic ActivityJAMA, 250
(1911)
The Pathological Anatomy of the Human Thyroid GlandArch. Int. Med., 7
Victor Horsley (1896)
A Discussion on the Pathology of Exophthalmic GoiterBrit. M. J., 2
W. Maccallum (1907)
THE PATHOLOGY OF EXOPHTHALMIC GOITER.JAMA
W. H. Welch (1888)
Demonstrations of Pathological Anatomy. Microscopical Specimens of the Thyroid Gland After Partial ExtirpationM. News, 3
A. Oswald (1902)
Die Chemie und Physiologie des KropfesVirchows Arch. f. path. Anat., 169
Abstract As early as 1600 B. C, the Chinese used the ash of seaweed and sponges in the treatment of goiter empirically. The use of iodine in this form continued through ancient, medieval and modern times until the introduction of the pure drug in the treatment of the thyroid gland by Coindet in 1820, which followed closely the isolation of iodine from the ash of burnt sponges and seaweed by Fyfe. Coindet reported excellent results following the administration of from five to twenty drops of the tincture daily. France used iodine extensively in the Department of the Seine about 1853. It was used in the form o.f a powder in the food or as an ointment, which is an interesting example of the popular use of iodine at this time. Baumann discovered that iodine was a normal constituent of the thyroid gland in 1895, and this gave a more reasonable basis References 1. Plummer, H. S.: The Clinical and Pathological Relationship of Simple and Exophthalmic Goiter , Am. J. M. Sc. 146:790-795, 1913.Crossref 2. Kendall, E. C.: The Isolation in Crystalline Form of the Compound Containing Iodin which Occurs in the Thyroid: Its Clinical Nature and Physiological Activity , Tr. A. Am. Phys. 30:420-449, 1915. 3. Plummer, H. S.: The Function of the Thyroid Gland , Collected Papers of The Mayo Clinic and The Mayo Foundation 17:473-499, 1925. 4. Plummer, H. S.: Functions of the Normal and Abnormal Thyroid Gland , Oxford Medicine, New York, Oxford University Press, 1921, vol. 3, pp. 839-873. 5. MacCallum, W. G.: The Pathology of Exophthalmic Goiter , J. A. M. A. 49:1158-1162 ( (Oct. 5) ) 1907.Crossref 6. Wilson, L. B.: The Relationship of the Clinical and Pathologic Aspects of Exophthalmic Goiter , Northwest. Med. 5:1-5, 1913 7. The Pathology of the Thyroid Gland in Exophthalmic Goiter , Am. J. M. Sc. 146:781-790, 1913Crossref 8. Notes on the Pathology of Simple and Exophthalmic Goiter , M. Rec. 84:373-378, 1913 9. A Study of the Pathology of the Thyroids from Cases of Toxic-Non-Exophthalmic Goiter , Journal-Lancet 34:93-97, 1914. 10. Hämig, Gottfried: Anatomische Untersuchungen über Morbus Basedowii , Arch. f. klin. Chir. 55:1-68, 1897. 11. Marine, David: On the Occurrence and Physiological Nature of Glandular Hyperplasia of the Thyroid (Dog and Sheep) Together with Remarks on Important Clinical Human Problems , Bull. Johns Hopkins Hosp. 18:359-364, 1907. 12. Horsley, Victor: The Pathology of the Thyroid Gland, Brown Lectures , Lancet 2:1163-1164, 1886. 13. Halsted, W. S.: An Experimental Study of the Thyroid Gland of Dogs with Special Consideration of Hypertrophy of this Gland , Rep. Johns Hopkins Hosp. 1:373-422, 1896. 14. Giordano, A. S., and Caylor, H. D.: Histological Study of the Effect of Ligation of the Thyroid Vessels in Exopthalmic Goiter , Surg. Gynec. Obst. 36:75-80, 1923. 15. Plummer, H. S., and Boothby, W. M.: The Value of Iodin in Exophthalmic Goiter , J. Iowa M. Soc. 14:66-73, 1924. 16. Wilson, L. B.: Personal communication to the author. 17. Marine, David; and Williams, W. W.: The Relation of Iodine to the Structure of the Thyroid Gland , Arch. Int. Med. 1:349-384 ( (May) ) 1908.Crossref 18. Wagener: Ueber die Folgen der Extirpation der Schilddrüse nach Versuchen an Thieren , Wien med. Bl. , 1884, nos. (25 and 30) . 19. Horsley, Victor: A Discussion on the Pathology of Exophthalmic Goiter , Brit. M. J. 2:895, 1896. 20. Welch, W. H.: Demonstrations of Pathological Anatomy. Microscopical Specimens of the Thyroid Gland After Partial Extirpation , M. News 3:455, 1888. 21. Halsted, W. S.: Factors Which May Be Concerned in Causing Hypertrophy of the Thyroid Gland and the Effect of Excision of this Organ upon Other of the Ductless Glands , Tr. A. Am. Phys. 28:127-135, 1913. 22. Oswald, A.: Die Chemie und Physiologie des Kropfes , Virchows Arch. f. path. Anat. 169:444-479, 1902.Crossref 23. Cattell, R. B.: The Pathology of Exophthalmic Goiter. A Histological and Chemical Study of the Change Following Administration of Iodine (Lugol's Solution) , Boston M. & S. J. 192:989-996, 1925. 24. Marine, David; and Lenhart, C. H.: The Colloid Glands (Goitres), Their Etiology and Physiological Significance , Bull. Johns Hopkins Hosp. 20:131-139, 1909 25. The Pathological Anatomy of the Human Thyroid Gland , Arch. Int. Med. 7:506-535 ( (April) ) 1911 26. Pathological Anatomy of Exophthalmic Goiter , Arch. Int. Med. 8:265-316 ( (Sept.) ) 1911. 27. Loeb, Leo: Studies on Compensatory Hypertrophy of Thyroid Gland: IV. The Influence of Iodine on Hypertrophy of the Thyroid Gland , J. M. Research 41:481-494, 1919-1920 28. Studies on Compensatory Hypertrophy of the Thyroid Gland: V. The Effect of the Administration of Thyroid, Thymus Gland and Tethelin and of a Meat Diet on the Hypertrophy of the Thyroid Gland in Guinea-Pigs , Loeb J. M. Research 42:77-89, 1921. 29. Loeb, Leo; and Kaplan, E. E.: Studies of Compensatory Hypertrophy of the Thyroid Gland: VI. The Effect of Feeding Anterior Lobe of the Pituitary Gland on the Hypertrophy of the Thyroid Gland in the Guinea-pig , J. M. Research 44:557-578, 1924. 30. Rienhoff, W. F.: The Historical Changes Brought About in Cases of Exophthalmic Goiter by the Administration of Iodine , Bull. Johns Hopkins Hosp. 37:285-306, 1925.
Archives of Surgery – American Medical Association
Published: Dec 1, 1927
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