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ORIGINAL ARTICLE Albumin Use Guidelines and Outcome in a Surgical Intensive Care Unit Anthony Charles, MD; Maryanne Purtill, MD; Sharon Dickinson, RN, MSN, CCRN; Michael Kraft, PharmD; Melissa Pleva, PharmD; Craig Meldrum, BBA; Lena Napolitano, MD Hypothesis: Restrictive albumin use guidelines in the costs were obtained from the pharmacy prospective surgical intensive care unit (SICU) will not increase mor- database. tality and will result in cost savings. Results: A total of 1361 patients were included in the study. A statistically significant reduction in albumin use (54%) Design: Prospective cohort study. was found in the fourth quarter (P=.004), and a substan- Setting: Tertiary teaching hospital. tial cost saving was realized (56% reduction in cost) with the albumin use guidelines. Restrictive use of albumin had Patients: All patients admitted to the SICU from July no negative impact on ICU mortality. Mean Acute Physi- 1, 2004, through July 1, 2005, were included in this ology and Chronic Health Evaluation III scores on ICU day study. 1 were not different. No significant difference in mean ICU length of stay was noted. Maintained reduction in the use Interventions: Patients in the first 3 quarters of the study of albumin was documented during the next
JAMA Surgery – American Medical Association
Published: Oct 1, 2008
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