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K. Perry, R. Fuller (1992)
Effect of fluoxetine on serotonin and dopamine concentration in microdialysis fluid from rat striatum.Life sciences, 50 22
V. Molina, S. Gobaille, P. Mandel (1986)
Effects of serotonin‐mimetic drugs on mouse‐killing behaviorAggressive Behavior, 12
C. Salzman, A. Wolfson, A. Schatzberg, J. Looper, Rebecca Henke, M. Albanese, J. Schwartz, E. Miyawaki (1995)
Effect of fluoxetine on anger in symptomatic volunteers with borderline personality disorder.Journal of clinical psychopharmacology, 15 1
R. Fuller (1994)
Uptake inhibitors increase extracellular serotonin concentration measured by brain microdialysis.Life sciences, 55 3
G. Brown, F. Goodwin (1984)
DIAGNOSTIC, CLINICAL AND PERSONALITY CHARACTERISTICS OF AGGRESSIVE MEN WITH LOW 5-HIAAClinical Neuropharmacology, 7
P. Markovitz, J. Calabrese, S. Schulz, Herbert Meltzer (1991)
Fluoxetine in the treatment of borderline and schizotypal personality disorders.The American journal of psychiatry, 148 8
R. Depue, M. Spoont (1986)
A Behavioral Dimension of ConstraintAnnals of the New York Academy of Sciences, 487
T. Kobylski (1988)
Diagnostic and Statistical Manual of Mental Disorders, Third Edition, RevisedPsychosomatics, 29
R. Kavoussi, Jennifer Liu, E. Coccaro (1994)
An open trial of sertraline in personality disordered patients with impulsive aggression.The Journal of clinical psychiatry, 55 4
E. Coccaro, J. Astill, J. Herbert, A. Schut (1990)
Fluoxetine treatment of impulsive aggression in DSM-III-R personality disorder patients.Journal of clinical psychopharmacology, 10 5
Spoont MR Depue RA (1986)
Conceptualizing a serotonin trait: a behavioral dimension of constraintAnn N Y Acad Sci, 487
M. Linnoila, M. Virkkunen, M. Scheinin, A. Nuutila, R. Rimón, F. Goodwin (1983)
Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentration differentiates impulsive from nonimpulsive violent behavior.Life sciences, 33 26
Handlesman L Bernstein DP (1995)
Neuropsychiatry of Behavior Disorders
H. Moss, J. Yao, G. Panzak (1990)
Serotonergic responsivity and behavioral dimensions in antisocial personality disorder with substance abuseBiological Psychiatry, 28
Fuller RW (1994)
Minireview: uptake inhibitors increase extracellular serotonin concentration measures by brain microdialysisLife Sci, 55
R. Limson, D. Goldman, A. Roy, D. Lamparski, B. Ravitz, B. Adinoff, M. Linnoila (1991)
Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls.Archives of general psychiatry, 48 5
B. Birmaher, Michael Stanley, Laurence Greenhill, Janet Twomey, Antigony Gavrilescu, Harris Rabinovich (1990)
Platelet imipramine binding in children and adolescents with impulsive behavior.Journal of the American Academy of Child and Adolescent Psychiatry, 29 6
M. Kruesi, J. Rapoport, S. Hamburger, E. Hibbs, William Potter, M. Lenane, Gerald Brown (1990)
Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents.Archives of general psychiatry, 47 5
Stone Mh (1989)
The role of pharmacotherapy in the treatment of patients with borderline personality disorder.Psychopharmacology Bulletin, 25
Candace Brown, T. Kent, S. Bryant, R. Gevedon, Jan Campbell, A. Felthous, E. Barratt, R. Rose (1989)
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M. Sheard, J. Marini (1978)
Treatment of human aggressive behavior: four case studies of the effect of lithium.Comprehensive psychiatry, 19 1
V. O’Keane, E. Moloney, Helen O’Neill, A. O'Connor, C. Smith, T. Dinan (1992)
Blunted Prolactin Responses to d-Fenfluramine in SociopathyBritish Journal of Psychiatry, 160
M. Virkkunen, R. Rawlings, R. Tokola, R. Poland, A. Guidotti, C. Nemeroff, G. Bissette, K. Kalogeras, S. Karonen, M. Linnoila (1994)
CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers.Archives of general psychiatry, 51 1
E. Coccaro, S. Gabriel, L. Siever (1990)
Buspirone challenge: preliminary evidence for a role for central 5-HT1a receptor function in impulsive aggressive behavior in humans.Psychopharmacology bulletin, 26 3
P. Blier, C. Montigny, Y. Chaput (1987)
Modifications of the Serotonin System by Antidepressant Treatments: Implications for the Therapeutic Response in Major DepressionJournal of Clinical Psychopharmacology, 7
A. DeLongis, S. Folkman, R. Lazarus (1988)
The impact of daily stress on health and mood: psychological and social resources as mediators.Journal of personality and social psychology, 54 3
Rapoport JL MJP (1990)
CSF metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescentsArch Gen Psychiatry, 47
Gerald Brown, F. Goodwin, J. Ballenger, P. Goyer, L. Major (1979)
Aggression in humans correlates with cerebrospinal fluid amine metabolitesPsychiatry Research, 1
R. Cowdry, D. Gardner (1988)
Pharmacotherapy of borderline personality disorder. Alprazolam, carbamazepine, trifluoperazine, and tranylcypromine.Archives of general psychiatry, 45 2
Daniel Klein, Paige Ouimette, Helen Kelly, Tova Ferro, L. Riso (1994)
Test-retest reliability of team consensus best-estimate diagnoses of axis I and II disorders in a family study.The American journal of psychiatry, 151 7
E. Coccaro, L. Siever, H. Klar, G. Maurer, Karen Cochrane, T. Cooper, R. Mohs, K. Davis (1989)
Serotonergic studies in patients with affective and personality disorders. Correlates with suicidal and impulsive aggressive behavior.Archives of general psychiatry, 46 7
Moloney E O'Keane V (1992)
Blunted prolactin responses to D-fenfluramine in sociopathy: evidence for subsensitivity of central serotonergic functionBr J Psychiatry, 160
Chang M Suckow RS (1992)
A sensitive and selective liquid chromatographic method using fluorescence detection for plasma fluoxetine and norfluoxetineClin Chem, 38
Siever LJ Coccaro EF (1989)
Serotonergic studies in affective and personality disorder patients: correlates with suicidal and impulsive aggressive behaviorArch Gen Psychiatry, 46
D. Marazziti, A. Rotondo, S. Presta, Maria Pancioli-Guadagnucci, L. Palego, L. Conti (1993)
Role of serotonin in human aggressive behaviourAggressive Behavior, 19
E. Coccaro, R. Kavoussi, Y. Sheline, J. Lish, J. Csernansky (1996)
Impulsive aggression in personality disorder correlates with tritiated paroxetine binding in the platelet.Archives of general psychiatry, 53 6
E. Coccaro, Philip Harvey, E. Kupsaw-Lawrence, J. Herbert, D. Bernstein (1991)
Development of neuropharmacologically based behavioral assessments of impulsive aggressive behavior.The Journal of neuropsychiatry and clinical neurosciences, 3 2
M. Sheard, J. Marini, C. Bridges, E. Wagner (1976)
The effect of lithium on impulsive aggressive behavior in man.The American journal of psychiatry, 133 12
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Maurizio Fava, J. Rosenbaum, J. Pava, Mary McCarthy, Ronald Steingard, E. Bouffides (1993)
Anger attacks in unipolar depression, Part 1: Clinical correlates and response to fluoxetine treatment.The American journal of psychiatry, 150 8
M. Norden (1989)
Fluoxetine in borderline personality disorderProgress in Neuro-Psychopharmacology and Biological Psychiatry, 13
Eichelman B (1995)
Impulsive Aggression and Disorders of Impulse Control
J. Heiligenstein, E. Coccaro, J. Potvin, C. Beasley, B. Dornseif, D. Masica (1992)
Fluoxetine Not Associated With Increased Violence or Aggression in Controlled Clinical TrialsAnnals of Clinical Psychiatry, 4
J. Leckman, D. Sholomskas, Douglas Thompson, Arthur Belanger, Myrna Weissman (1982)
Best estimate of lifetime psychiatric diagnosis: a methodological study.Archives of general psychiatry, 39 8
Gerald Brown, M. Ebert, P. Goyer, D. Jimerson, W. Klein, W. Bunney, F. Goodwin (1982)
Aggression, suicide, and serotonin: relationships to CSF amine metabolites.The American journal of psychiatry, 139 6
Calabrese JR Markovitz PJ (1991)
Fluoxetine in borderline and schizotypal personality disorderAm J Psychiatry, 148
E. Coccaro (1993)
Psychopharmacologic studies in patients with personality disorders: review and perspectiveJournal of Personality Disorders, 7
Yudofsky SC Silver JM (1986)
Biological Psychiatry
J. Cornelius, P. Soloff, J. Perel, R. Ulrich (1990)
Fluoxetine trial in borderline personality disorder.Psychopharmacology bulletin, 26 1
J. Cornelius, P. Soloff, James Perel, Richard Ulrich (1993)
Continuation pharmacotherapy of borderline personality disorder with haloperidol and phenelzine.The American journal of psychiatry, 150 12
Zimmerman Pfohl B (1989)
Structured Interview for the Diagnosis of DSM-III-R Personality Disorders
Martin Teicher, C. Glod, S. Aaronson, P. Gunter, A. Schatzberg, J. Cole (1989)
Open assessment of the safety and efficacy of thioridazine in the treatment of patients with borderline personality disorder.Psychopharmacology bulletin, 25 4
R. Suckow, M. Zhang, T. Cooper (1992)
Sensitive and selective liquid-chromatographic assay of fluoxetine and norfluoxetine in plasma with fluorescence detection after precolumn derivatization.Clinical chemistry, 38 9
Endicott J Spitzer RL (1978)
Schedule for Affective Disorders and Schizophrenia
Abstract Background: Evidence of an inverse relationship between central serotonergic (serotonin [5-hydroxytryptamine]) system function and impulsive aggressive behavior has been accumulating for more than 2 decades. If so, pharmacological enhancement of serotonin activity should be expected to reduce impulsive aggressive behavior in subjects in whom this behavior is prominent. Methods: A double-blind, placebo-controlled trial of the selective serotonin-uptake inhibitor fluoxetine hydrochloride was conducted in 40 nonmajor-depressed, nonbipolar or schizophrenic, DSM-III-R personality—disordered individuals with current histories of impulsive aggressive behavior and irritability. Measures included the Overt Aggression Scale—Modified for Outpatients, Clinical Global Impression Rating of Improvement, and several secondary measures of aggression, depression, and anxiety. 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Archives of General Psychiatry – American Medical Association
Published: Dec 1, 1997
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