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N. Andreasen, H. Nasrallah, Ronnie Dunn, S. Olson, W. Grove, J. Ehrhardt, J. Coffman, J. Crossett (1986)
Structural abnormalities in the frontal system in schizophrenia. A magnetic resonance imaging study.Archives of general psychiatry, 43 2
L. DeLisi, L. Goldin, J. Hamovit, M. Maxwell, D. Kurtz, E. Gershon (1986)
A family study of the association of increased ventricular size with schizophrenia.Archives of general psychiatry, 43 2
G. Nellhaus (1968)
Head circumference from birth to eighteen years. Practical composite international and interracial graphs.Pediatrics, 41 1
Jerison JJ (1973)
The Evolution of the Brain and Intelligence
H. Birx, R. Leakey, E. Dutton, S. Gould, W. Norton (1981)
The Mismeasure of ManBioScience
Broca P (1861)
Sur le volume et la forme du cerveau suivant les individus et suivant les races:Bull Soc Anthropol Paris, 2
Nellhaus G (1968)
Head circumference from birth to 18 yearsPediatrics, 41
Abstract To the Editor.— The recent report of an MRI study of the brains of schizophrenic patients compared with normal controls1 is of interest to us. Dr Andreasen and colleagues propose, on the basis of measurements performed on a midsagittal brain image, that schizophrenic men have smaller brains and craniums than normal men. They further suggest that this is consistent with an early developmental dysplastic process.To explore this proposal further, we reexamined our CT data that were reported in the same issue of the ARCHIVES.2 Total brain circumference from two CT slices that visualize the lateral ventricles were used for comparisons. Heights of all individuals were obtained. Total brain area was significantly smaller in the schizophrenic patients (N = 26) compared with controls (N = 20) for the slice maximally visualizing the lateral ventricles (t = 2.05, P =.05), but not different from controls for the slice taken through the maximal area of the References 1. Andreasen N, Nasrallah HA, Dunn V, Olson SC, Grove WM, Ehrhardt JC, Coffman JA, Crossett JHW: Structural abnormalities in the frontal system in schizophrenia: A magnetic resonance imaging study . Arch Gen Psychiatry 1986;43:136-144.Crossref 2. DeLisi LE, Goldin LR, Hamovit JR, Maxwell ME, Kurtz D, Gershon ES: A family study of the association of increased ventricular size with schizophrenia . Arch Gen Psychiatry 1986;43:148-153.Crossref 3. Nellhaus G: Head circumference from birth to 18 years . Pediatrics 1968;41:106-114. 4. Gould SJ: The Mismeasure of Man . New York, WW Norton Co, 1981. 5. Broca P: Sur le volume et la forme du cerveau suivant les individus et suivant les races: Bull Soc Anthropol Paris 1861;2:139-207. 6. Jerison JJ: The Evolution of the Brain and Intelligence . New York, Academic Press, 1973.
Archives of General Psychiatry – American Medical Association
Published: Jul 1, 1987
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