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Hat Size in Schizophrenia

Hat Size in Schizophrenia Abstract To the Editor.— The recent report of an MRI study of the brains of schizophrenic patients compared with normal controls1 is of interest to us. Dr Andreasen and colleagues propose, on the basis of measurements performed on a midsagittal brain image, that schizophrenic men have smaller brains and craniums than normal men. They further suggest that this is consistent with an early developmental dysplastic process.To explore this proposal further, we reexamined our CT data that were reported in the same issue of the ARCHIVES.2 Total brain circumference from two CT slices that visualize the lateral ventricles were used for comparisons. Heights of all individuals were obtained. Total brain area was significantly smaller in the schizophrenic patients (N = 26) compared with controls (N = 20) for the slice maximally visualizing the lateral ventricles (t = 2.05, P =.05), but not different from controls for the slice taken through the maximal area of the References 1. Andreasen N, Nasrallah HA, Dunn V, Olson SC, Grove WM, Ehrhardt JC, Coffman JA, Crossett JHW: Structural abnormalities in the frontal system in schizophrenia: A magnetic resonance imaging study . Arch Gen Psychiatry 1986;43:136-144.Crossref 2. DeLisi LE, Goldin LR, Hamovit JR, Maxwell ME, Kurtz D, Gershon ES: A family study of the association of increased ventricular size with schizophrenia . Arch Gen Psychiatry 1986;43:148-153.Crossref 3. Nellhaus G: Head circumference from birth to 18 years . Pediatrics 1968;41:106-114. 4. Gould SJ: The Mismeasure of Man . New York, WW Norton Co, 1981. 5. Broca P: Sur le volume et la forme du cerveau suivant les individus et suivant les races: Bull Soc Anthropol Paris 1861;2:139-207. 6. Jerison JJ: The Evolution of the Brain and Intelligence . New York, Academic Press, 1973. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of General Psychiatry American Medical Association

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References (7)

Publisher
American Medical Association
Copyright
Copyright © 1987 American Medical Association. All Rights Reserved.
ISSN
0003-990X
eISSN
1598-3636
DOI
10.1001/archpsyc.1987.01800190092015
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— The recent report of an MRI study of the brains of schizophrenic patients compared with normal controls1 is of interest to us. Dr Andreasen and colleagues propose, on the basis of measurements performed on a midsagittal brain image, that schizophrenic men have smaller brains and craniums than normal men. They further suggest that this is consistent with an early developmental dysplastic process.To explore this proposal further, we reexamined our CT data that were reported in the same issue of the ARCHIVES.2 Total brain circumference from two CT slices that visualize the lateral ventricles were used for comparisons. Heights of all individuals were obtained. Total brain area was significantly smaller in the schizophrenic patients (N = 26) compared with controls (N = 20) for the slice maximally visualizing the lateral ventricles (t = 2.05, P =.05), but not different from controls for the slice taken through the maximal area of the References 1. Andreasen N, Nasrallah HA, Dunn V, Olson SC, Grove WM, Ehrhardt JC, Coffman JA, Crossett JHW: Structural abnormalities in the frontal system in schizophrenia: A magnetic resonance imaging study . Arch Gen Psychiatry 1986;43:136-144.Crossref 2. DeLisi LE, Goldin LR, Hamovit JR, Maxwell ME, Kurtz D, Gershon ES: A family study of the association of increased ventricular size with schizophrenia . Arch Gen Psychiatry 1986;43:148-153.Crossref 3. Nellhaus G: Head circumference from birth to 18 years . Pediatrics 1968;41:106-114. 4. Gould SJ: The Mismeasure of Man . New York, WW Norton Co, 1981. 5. Broca P: Sur le volume et la forme du cerveau suivant les individus et suivant les races: Bull Soc Anthropol Paris 1861;2:139-207. 6. Jerison JJ: The Evolution of the Brain and Intelligence . New York, Academic Press, 1973.

Journal

Archives of General PsychiatryAmerican Medical Association

Published: Jul 1, 1987

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