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Unipolar and Bipolar Depressive Illness: Phenomenology and Response to Electroconvulsive Therapy

Unipolar and Bipolar Depressive Illness: Phenomenology and Response to Electroconvulsive Therapy Abstract We reviewed the records and depression rating-scale scores of 43 patients with endogenous depression who received electroconvulsive therapy (ECT) and classified them as having unipolar or bipolar depressive illness. We found no differences between 28 unipolar and 15 bipolar depressive patients for the severity of illness, the clinical psychopathology of the depressive syndrome, or the response to ECT. Bipolar patients had an earlier age at illness onset, an excess of women, a greater incidence of cyclothymia and mesomorphy, and a greater genetic loading for affective illness. Despite the differentiation of unipolar and bipolar depressives by various biological criteria they exhibit a homogeneous syndrome of endogenous depression and a uniform response to ECT. References 1. Leonhard K: Aufteilung der endogenen psychosen , ed 2. Berlin, Akademie Verlag, 1959. 2. Leonhard K, Korff I, Schultz H: Die tempermente in den familien der monopolaren un bipolaren phasichen psychosen . Psychiatr Neurol 143:416-434, 1962.Crossref 3. Perris C: A study of bipolar (manic-depressive) and unipolar recurrent depressive psychoses . Acta Psychiatr Scand [Suppl] 42:194, 1966. 4. Beigel A, Murphy D: Unipolar and bipolar affective illness . Arch Gen Psychiatry 24:215-220, 1971.Crossref 5. Strömgren LS: Unilateral versus bilateral electroconvulsive therapy . Acta Psychiatr Scand [Suppl] 49:240, 1973. 6. Abrams R, et al: Unilateral and bilateral electroconvulsive therapy . Arch Gen Psychiatry 27:88-91, 1972.Crossref 7. Hamilton M: A rating scale for depression . J Neurol Neurosurg Psychiatry 23:56-62, 1960.Crossref 8. Abrams R, Taylor M: Anterior bifrontal ECT: A clinical trial . Br J Psychiatry 122:587-590, 1973.Crossref 9. Baker M, et al: Depressive disease . Arch Gen Psychiatry 27:320-327, 1972.Crossref 10. Guze S, Goodwin D, Crane J: Criminality and psychiatric disorders . Arch Gen Psychiatry 20:583-591, 1969.Crossref 11. Slater E, Roth M: Clinical Psychiatry . New York, Williams & Wilkins Co, 1969. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of General Psychiatry American Medical Association

Unipolar and Bipolar Depressive Illness: Phenomenology and Response to Electroconvulsive Therapy

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References (15)

Publisher
American Medical Association
Copyright
Copyright © 1974 American Medical Association. All Rights Reserved.
ISSN
0003-990X
eISSN
1598-3636
DOI
10.1001/archpsyc.1974.01760090038006
Publisher site
See Article on Publisher Site

Abstract

Abstract We reviewed the records and depression rating-scale scores of 43 patients with endogenous depression who received electroconvulsive therapy (ECT) and classified them as having unipolar or bipolar depressive illness. We found no differences between 28 unipolar and 15 bipolar depressive patients for the severity of illness, the clinical psychopathology of the depressive syndrome, or the response to ECT. Bipolar patients had an earlier age at illness onset, an excess of women, a greater incidence of cyclothymia and mesomorphy, and a greater genetic loading for affective illness. Despite the differentiation of unipolar and bipolar depressives by various biological criteria they exhibit a homogeneous syndrome of endogenous depression and a uniform response to ECT. References 1. Leonhard K: Aufteilung der endogenen psychosen , ed 2. Berlin, Akademie Verlag, 1959. 2. Leonhard K, Korff I, Schultz H: Die tempermente in den familien der monopolaren un bipolaren phasichen psychosen . Psychiatr Neurol 143:416-434, 1962.Crossref 3. Perris C: A study of bipolar (manic-depressive) and unipolar recurrent depressive psychoses . Acta Psychiatr Scand [Suppl] 42:194, 1966. 4. Beigel A, Murphy D: Unipolar and bipolar affective illness . Arch Gen Psychiatry 24:215-220, 1971.Crossref 5. Strömgren LS: Unilateral versus bilateral electroconvulsive therapy . Acta Psychiatr Scand [Suppl] 49:240, 1973. 6. Abrams R, et al: Unilateral and bilateral electroconvulsive therapy . Arch Gen Psychiatry 27:88-91, 1972.Crossref 7. Hamilton M: A rating scale for depression . J Neurol Neurosurg Psychiatry 23:56-62, 1960.Crossref 8. Abrams R, Taylor M: Anterior bifrontal ECT: A clinical trial . Br J Psychiatry 122:587-590, 1973.Crossref 9. Baker M, et al: Depressive disease . Arch Gen Psychiatry 27:320-327, 1972.Crossref 10. Guze S, Goodwin D, Crane J: Criminality and psychiatric disorders . Arch Gen Psychiatry 20:583-591, 1969.Crossref 11. Slater E, Roth M: Clinical Psychiatry . New York, Williams & Wilkins Co, 1969.

Journal

Archives of General PsychiatryAmerican Medical Association

Published: Mar 1, 1974

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