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Infant Pertussis Epidemiology and Implications for Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis (Tdap) Vaccination

Infant Pertussis Epidemiology and Implications for Tetanus Toxoid, Reduced Diphtheria Toxoid, and... ARTICLE Infant Pertussis Epidemiology and Implications for Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis (Tdap) Vaccination King County, Washington, 2002 Through 2007 Matthew P. Hanson, MD, DTM&H; Tao S. Kwan-Gett, MD, MPH; Atar Baer, PhD; Krista Rietberg, MPH; Mara Ohrt, MPH; Jeffrey S. Duchin, MD Objectives: To describe the epidemiology of infant Results: Among 176 confirmed cases of infants with per- pertussis in King County, Washington, and to better tussis,themedianagewas3months(agerange,0-11months); 80.1%wereyoungerthan6months.Seventy-sevenpercent understand the implications for tetanus toxoid, wereage-appropriatelyvaccinated.Between2002and2007, reduced diphtheria toxoid, and acellular pertussis theoverallmeanannualincidencewas136casesper100 000 (Tdap) vaccination among older children, adolescents, infantpopulation.Comparedwithameanannualincidence and adults. of73casesper100 000infantpopulationamongwhites,the incidencewas246casesper100 000infantpopulationamong Design: Retrospective analysis of reported pertussis cases blacks (rate ratio [RR], 3.37; 95% confidence interval [CI], among infants younger than 1 year, January 1, 2002, 2.59-4.44)and194casesper100 000infantpopulationamong through December 31, 2007. Hispanics (RR, 2.66; 95% CI, 2.02-3.53). Households were the suspected exposure location for 70.0% of cases. Case Setting: King County, Washington. households had a median of 3 (range, 1-15) Tdap-eligible persons. Participants: Reported pertussis cases among infants younger than 1 year between 2002 and 2007. Conclusions: The burden of infant pertussis in King County, Washington, was high between 2002 and 2007, Main Outcome Measures: Bordetella pertussis from especially http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

Infant Pertussis Epidemiology and Implications for Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis (Tdap) Vaccination

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References (36)

Publisher
American Medical Association
Copyright
Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/archpediatrics.2011.85
pmid
21727277
Publisher site
See Article on Publisher Site

Abstract

ARTICLE Infant Pertussis Epidemiology and Implications for Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis (Tdap) Vaccination King County, Washington, 2002 Through 2007 Matthew P. Hanson, MD, DTM&H; Tao S. Kwan-Gett, MD, MPH; Atar Baer, PhD; Krista Rietberg, MPH; Mara Ohrt, MPH; Jeffrey S. Duchin, MD Objectives: To describe the epidemiology of infant Results: Among 176 confirmed cases of infants with per- pertussis in King County, Washington, and to better tussis,themedianagewas3months(agerange,0-11months); 80.1%wereyoungerthan6months.Seventy-sevenpercent understand the implications for tetanus toxoid, wereage-appropriatelyvaccinated.Between2002and2007, reduced diphtheria toxoid, and acellular pertussis theoverallmeanannualincidencewas136casesper100 000 (Tdap) vaccination among older children, adolescents, infantpopulation.Comparedwithameanannualincidence and adults. of73casesper100 000infantpopulationamongwhites,the incidencewas246casesper100 000infantpopulationamong Design: Retrospective analysis of reported pertussis cases blacks (rate ratio [RR], 3.37; 95% confidence interval [CI], among infants younger than 1 year, January 1, 2002, 2.59-4.44)and194casesper100 000infantpopulationamong through December 31, 2007. Hispanics (RR, 2.66; 95% CI, 2.02-3.53). Households were the suspected exposure location for 70.0% of cases. Case Setting: King County, Washington. households had a median of 3 (range, 1-15) Tdap-eligible persons. Participants: Reported pertussis cases among infants younger than 1 year between 2002 and 2007. Conclusions: The burden of infant pertussis in King County, Washington, was high between 2002 and 2007, Main Outcome Measures: Bordetella pertussis from especially

Journal

JAMA PediatricsAmerican Medical Association

Published: Jul 1, 2011

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