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ARTICLE Infant Pertussis Epidemiology and Implications for Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis (Tdap) Vaccination King County, Washington, 2002 Through 2007 Matthew P. Hanson, MD, DTM&H; Tao S. Kwan-Gett, MD, MPH; Atar Baer, PhD; Krista Rietberg, MPH; Mara Ohrt, MPH; Jeffrey S. Duchin, MD Objectives: To describe the epidemiology of infant Results: Among 176 confirmed cases of infants with per- pertussis in King County, Washington, and to better tussis,themedianagewas3months(agerange,0-11months); 80.1%wereyoungerthan6months.Seventy-sevenpercent understand the implications for tetanus toxoid, wereage-appropriatelyvaccinated.Between2002and2007, reduced diphtheria toxoid, and acellular pertussis theoverallmeanannualincidencewas136casesper100 000 (Tdap) vaccination among older children, adolescents, infantpopulation.Comparedwithameanannualincidence and adults. of73casesper100 000infantpopulationamongwhites,the incidencewas246casesper100 000infantpopulationamong Design: Retrospective analysis of reported pertussis cases blacks (rate ratio [RR], 3.37; 95% confidence interval [CI], among infants younger than 1 year, January 1, 2002, 2.59-4.44)and194casesper100 000infantpopulationamong through December 31, 2007. Hispanics (RR, 2.66; 95% CI, 2.02-3.53). Households were the suspected exposure location for 70.0% of cases. Case Setting: King County, Washington. households had a median of 3 (range, 1-15) Tdap-eligible persons. Participants: Reported pertussis cases among infants younger than 1 year between 2002 and 2007. Conclusions: The burden of infant pertussis in King County, Washington, was high between 2002 and 2007, Main Outcome Measures: Bordetella pertussis from especially
JAMA Pediatrics – American Medical Association
Published: Jul 1, 2011
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