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Male Circumcision for the Prevention of Acquisition and Transmission of Sexually Transmitted Infections

Male Circumcision for the Prevention of Acquisition and Transmission of Sexually Transmitted... REVIEW ARTICLE Male Circumcision for the Prevention of Acquisition and Transmission of Sexually Transmitted Infections The Case for Neonatal Circumcision Aaron A. R. Tobian, MD, PhD; Ronald H. Gray, MD, MSc; Thomas C. Quinn, MD, MSc he American Academy of Pediatrics (AAP) male circumcision policy states that while there are potential medical benefits of newborn male circumcision, the data are insuf- ficient to recommend routine neonatal circumcision. Since 2005, however, 3 random- T ized trials have evaluated male circumcision for prevention of sexually transmitted in- fections. The trials found that circumcision decreases human immunodeficiency virus acquisition by 53% to 60%, herpes simplex virus type 2 acquisition by 28% to 34%, and human papillomavi- rus prevalence by 32% to 35% in men. Among female partners of circumcised men, bacterial vagi- nosis was reduced by 40%, and Trichomonas vaginalis infection was reduced by 48%. Genital ulcer disease was also reduced among males and their female partners. These findings are also sup- ported by observational studies conducted in the United States. The AAP policy has a major im- pact on neonatal circumcision in the United States. This review evaluates the recent data that sup- port revision of the AAP policy to fully http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

Male Circumcision for the Prevention of Acquisition and Transmission of Sexually Transmitted Infections

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References (80)

Publisher
American Medical Association
Copyright
Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/archpediatrics.2009.232
pmid
20048246
Publisher site
See Article on Publisher Site

Abstract

REVIEW ARTICLE Male Circumcision for the Prevention of Acquisition and Transmission of Sexually Transmitted Infections The Case for Neonatal Circumcision Aaron A. R. Tobian, MD, PhD; Ronald H. Gray, MD, MSc; Thomas C. Quinn, MD, MSc he American Academy of Pediatrics (AAP) male circumcision policy states that while there are potential medical benefits of newborn male circumcision, the data are insuf- ficient to recommend routine neonatal circumcision. Since 2005, however, 3 random- T ized trials have evaluated male circumcision for prevention of sexually transmitted in- fections. The trials found that circumcision decreases human immunodeficiency virus acquisition by 53% to 60%, herpes simplex virus type 2 acquisition by 28% to 34%, and human papillomavi- rus prevalence by 32% to 35% in men. Among female partners of circumcised men, bacterial vagi- nosis was reduced by 40%, and Trichomonas vaginalis infection was reduced by 48%. Genital ulcer disease was also reduced among males and their female partners. These findings are also sup- ported by observational studies conducted in the United States. The AAP policy has a major im- pact on neonatal circumcision in the United States. This review evaluates the recent data that sup- port revision of the AAP policy to fully

Journal

JAMA Pediatrics – American Medical Association

Published: Jan 1, 2010

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