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Pseudotumor Cerebri in a Boy With Systemic Lupus Erythematosus

Pseudotumor Cerebri in a Boy With Systemic Lupus Erythematosus Abstract Sir.—Systemic lupus erythematosus (SLE) is an episodic, multisystem disease of unknown origin characterized by widespread chronic inflammatory involvement of the connective tissue. Often there is prominent vasculitis of the small blood vessels.1,2 In the first two decades of life central nervous system involvement in SLE has been reported to range from 9% to 45%.2 Pseudotumor cerebri is a form of central nervous system involvement that is quite rare. We present herein the first report, to our knowledge, of a boy with pseudotumor cerebri as an initial manifestation of SLE. Patient Report.—A 9-year-old boy was referred from a general hospital in December 1988 with the diagnosis of nephritis and persistent headache. He had a history of edema and headache 1 month before admission. Laboratory findings at the referring hospital were compatible with acute glomerulonephritis; serum urea nitrogen and creatinine levels were 11.0 mmol/L of urea and 170 References 1. Fish AJ, Blau EB, Westberg NG, Burke BA, Vernier RL, Michael AF. Systemic lupus erythematosus within the first two decades of life . Am J Med. 1977;62:99-117.Crossref 2. Cassidy JT, Sullivan DB, Petty RE, Ragsdale C. Lupus nephritis and encephalopathy prognosis in 58 children . Arthritis Rheum . 1977;20:315-322. 3. Couch R, Camfield PR, Tibbles JAR. The changing picture of pseudotumor cerebri in children . Can J Neurol Sci . 1985;12:48-50. 4. Silberberg DH, Laties AM. Increased intracranial pressure in disseminated lupus erythematosus . Arch Neurol . 1973;29:88-90.Crossref 5. Delgiudice GC, Scher CA, Athreya BH, Diamond GR. Pseudotumor cerebri and childhood systemic lupus erythematosus . J Rheumatol . 1986;13:748-752. 6. Carlow TJ, Glaser JS. Pseudotumor cerebri syndrome in systemic lupus erythematosus . JAMA . 1974;288:197-200.Crossref 7. Van Dop C. Alternate causes of pseudotumor cerebri . AJDC . 1985;139:545-546. 8. Yancey CL, Doughty RA, Athreya BH. Central nervous system involvement in childhood systemic lupus erythematosus . Arthritis Rheum . 1981;24:1389-1395.Crossref 9. Bettman JW Jr, Daroff RB, Sanders MD, Hoyt WF. Papilledema and asymptomatic intracranial hypertension in systemic lupus erythematosus . Arch Ophthalmol . 1968;80:189-193.Crossref 10. Kaplan RE, Springate JE, Feld LG, Cohen ME. Pseudotumor cerebri associated with cerebral venous sinus thrombosis, internal jugular vein thrombosis, and systemic lupus erythematosus . J Pediatr . 1985;107:266-268.Crossref 11. Weisberg LA, Chutorian AM. Pseudotumor cerebri of childhood . AJDC . 1977;131:1243-1248. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Pseudotumor Cerebri in a Boy With Systemic Lupus Erythematosus

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References (12)

Publisher
American Medical Association
Copyright
Copyright © 1992 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1992.02160240027008
Publisher site
See Article on Publisher Site

Abstract

Abstract Sir.—Systemic lupus erythematosus (SLE) is an episodic, multisystem disease of unknown origin characterized by widespread chronic inflammatory involvement of the connective tissue. Often there is prominent vasculitis of the small blood vessels.1,2 In the first two decades of life central nervous system involvement in SLE has been reported to range from 9% to 45%.2 Pseudotumor cerebri is a form of central nervous system involvement that is quite rare. We present herein the first report, to our knowledge, of a boy with pseudotumor cerebri as an initial manifestation of SLE. Patient Report.—A 9-year-old boy was referred from a general hospital in December 1988 with the diagnosis of nephritis and persistent headache. He had a history of edema and headache 1 month before admission. Laboratory findings at the referring hospital were compatible with acute glomerulonephritis; serum urea nitrogen and creatinine levels were 11.0 mmol/L of urea and 170 References 1. Fish AJ, Blau EB, Westberg NG, Burke BA, Vernier RL, Michael AF. Systemic lupus erythematosus within the first two decades of life . Am J Med. 1977;62:99-117.Crossref 2. Cassidy JT, Sullivan DB, Petty RE, Ragsdale C. Lupus nephritis and encephalopathy prognosis in 58 children . Arthritis Rheum . 1977;20:315-322. 3. Couch R, Camfield PR, Tibbles JAR. The changing picture of pseudotumor cerebri in children . Can J Neurol Sci . 1985;12:48-50. 4. Silberberg DH, Laties AM. Increased intracranial pressure in disseminated lupus erythematosus . Arch Neurol . 1973;29:88-90.Crossref 5. Delgiudice GC, Scher CA, Athreya BH, Diamond GR. Pseudotumor cerebri and childhood systemic lupus erythematosus . J Rheumatol . 1986;13:748-752. 6. Carlow TJ, Glaser JS. Pseudotumor cerebri syndrome in systemic lupus erythematosus . JAMA . 1974;288:197-200.Crossref 7. Van Dop C. Alternate causes of pseudotumor cerebri . AJDC . 1985;139:545-546. 8. Yancey CL, Doughty RA, Athreya BH. Central nervous system involvement in childhood systemic lupus erythematosus . Arthritis Rheum . 1981;24:1389-1395.Crossref 9. Bettman JW Jr, Daroff RB, Sanders MD, Hoyt WF. Papilledema and asymptomatic intracranial hypertension in systemic lupus erythematosus . Arch Ophthalmol . 1968;80:189-193.Crossref 10. Kaplan RE, Springate JE, Feld LG, Cohen ME. Pseudotumor cerebri associated with cerebral venous sinus thrombosis, internal jugular vein thrombosis, and systemic lupus erythematosus . J Pediatr . 1985;107:266-268.Crossref 11. Weisberg LA, Chutorian AM. Pseudotumor cerebri of childhood . AJDC . 1977;131:1243-1248.

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Dec 1, 1992

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