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Hyperpyrexia, Hemorrhagic Shock and Encephalopathy, and Creatinine Phosphokinase

Hyperpyrexia, Hemorrhagic Shock and Encephalopathy, and Creatinine Phosphokinase Abstract Sir.—In his October 1990 editorial in AJDC, Corrigan1 recommends that the "H" in the syndrome of hemorrhagic shock and encephalopathy (HSE) stand for hyperpyrexia. This is a welcome suggestion to the clinician because it underscores hyperpyrexia as an important clue to the diagnosis of this new syndrome. In February 1985, we were at a loss to explain a difficult patient who showed clinical symptoms of heatstroke. The original description of HSE by Levin et al2 in 1983 did not view hyperpyrexia as a prominent feature of this disorder. Only two of the 10 patients described had temperatures of 41°C or greater. It was not until a subsequent report3 emphasized hyperpyrexia that we were alerted to the similarity between our case and those being described in the literature. Patient Report.—A 3-year-old black girl was well until 11 pm on the evening of admission, when she vomited References 1. Corrigan JJ Jr. The 'H' in hemorrhagic shock and encephalopathy syndrome should be 'hyperpyrexia.' AJDC . 1990;144:1077. 2. Levin M, Kay JDS, Gould JD, Hjelm M, Pincott JR, Dinwiddie R. Haemorrhagic shock and encephalopathy: a new syndrome with a high mortality in young children . Lancet . 1983;2:64-67.Crossref 3. Caspe WB, Nucci AT, Sangho C. Extreme hyperpyrexia in childhood: presentation similar to hemorrhagic shock and encephalopathy . Clin Pediatr . 1989;28:76-80.Crossref 4. Chaves-Carballo E, Montes JE, Nelson WB, Chrenka BA. Hemorrhagic shock and encephalopathy: clinical definition of a catastrophic syndrome in infants . AJDC . 1990;144:1079-1082. 5. Tucker L, Stanford J, Graves B, Swetnam J, Hamburger S, Anwar A. Classic heatstroke: clinical and laboratory assessment . South Med J . 1985;78:20-25.Crossref 6. Beaufils F, Aujard Y. Haemorrhagic shock and encephalopathy syndrome . Lancet . 1983;2:1086.Crossref 7. Sofer S, Philip M, Hershkowit J, Bennett H. Hemorrhagic shock and encephalopathy syndrome . AJDC . 1986; 140:1252-1254. 8. Roth B, Younossi-Hartenstein A, Schroder R, Hornchen H, Heymans L. Haemorrhagic shock-encephalopathy syndrome . Eur J Pediatr . 1987;146:83-85.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Hyperpyrexia, Hemorrhagic Shock and Encephalopathy, and Creatinine Phosphokinase

Hyperpyrexia, Hemorrhagic Shock and Encephalopathy, and Creatinine Phosphokinase

Abstract

Abstract Sir.—In his October 1990 editorial in AJDC, Corrigan1 recommends that the "H" in the syndrome of hemorrhagic shock and encephalopathy (HSE) stand for hyperpyrexia. This is a welcome suggestion to the clinician because it underscores hyperpyrexia as an important clue to the diagnosis of this new syndrome. In February 1985, we were at a loss to explain a difficult patient who showed clinical symptoms of heatstroke. The original description of HSE by Levin et al2 in 1983...
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References (12)

Publisher
American Medical Association
Copyright
Copyright © 1991 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1991.02160070013004
Publisher site
See Article on Publisher Site

Abstract

Abstract Sir.—In his October 1990 editorial in AJDC, Corrigan1 recommends that the "H" in the syndrome of hemorrhagic shock and encephalopathy (HSE) stand for hyperpyrexia. This is a welcome suggestion to the clinician because it underscores hyperpyrexia as an important clue to the diagnosis of this new syndrome. In February 1985, we were at a loss to explain a difficult patient who showed clinical symptoms of heatstroke. The original description of HSE by Levin et al2 in 1983 did not view hyperpyrexia as a prominent feature of this disorder. Only two of the 10 patients described had temperatures of 41°C or greater. It was not until a subsequent report3 emphasized hyperpyrexia that we were alerted to the similarity between our case and those being described in the literature. Patient Report.—A 3-year-old black girl was well until 11 pm on the evening of admission, when she vomited References 1. Corrigan JJ Jr. The 'H' in hemorrhagic shock and encephalopathy syndrome should be 'hyperpyrexia.' AJDC . 1990;144:1077. 2. Levin M, Kay JDS, Gould JD, Hjelm M, Pincott JR, Dinwiddie R. Haemorrhagic shock and encephalopathy: a new syndrome with a high mortality in young children . Lancet . 1983;2:64-67.Crossref 3. Caspe WB, Nucci AT, Sangho C. Extreme hyperpyrexia in childhood: presentation similar to hemorrhagic shock and encephalopathy . Clin Pediatr . 1989;28:76-80.Crossref 4. Chaves-Carballo E, Montes JE, Nelson WB, Chrenka BA. Hemorrhagic shock and encephalopathy: clinical definition of a catastrophic syndrome in infants . AJDC . 1990;144:1079-1082. 5. Tucker L, Stanford J, Graves B, Swetnam J, Hamburger S, Anwar A. Classic heatstroke: clinical and laboratory assessment . South Med J . 1985;78:20-25.Crossref 6. Beaufils F, Aujard Y. Haemorrhagic shock and encephalopathy syndrome . Lancet . 1983;2:1086.Crossref 7. Sofer S, Philip M, Hershkowit J, Bennett H. Hemorrhagic shock and encephalopathy syndrome . AJDC . 1986; 140:1252-1254. 8. Roth B, Younossi-Hartenstein A, Schroder R, Hornchen H, Heymans L. Haemorrhagic shock-encephalopathy syndrome . Eur J Pediatr . 1987;146:83-85.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Jul 1, 1991

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