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Scarring Retinopathy of Prematurity-Reply

Scarring Retinopathy of Prematurity-Reply Abstract In Reply.—We appreciate Dr Brown's interest in our recent report. We are aware of the problems raised by him, problems that occur in any retrospective clinical study and for which there are no completely adequate solutions. The problem of transfer bias does not seem to us to be as severe a problem as he describes since the transfer was based on status of a patient's respiratory disease and was not related to the severity of the patient's eye disease. In fact, transfer occurred before eye disease status was known. In addition, transfer decisions were made in a reasonably uniform manner for all patients. The question of the appropriate number of df for the t test raises the question of how to handle an imperfect data set. Our system of obtaining weighted average values for each of the 92 patients was an attempt to make the most appropriate use we References 1. Brown DR, Milley JR, Ripepi UJ, et al: Retinopathy of prematurity: Risk factors in a five-year cohort of critically ill premature neonates . AJDC 1987;141:154-160. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Scarring Retinopathy of Prematurity-Reply

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Scarring Retinopathy of Prematurity-Reply

Abstract

Abstract In Reply.—We appreciate Dr Brown's interest in our recent report. We are aware of the problems raised by him, problems that occur in any retrospective clinical study and for which there are no completely adequate solutions. The problem of transfer bias does not seem to us to be as severe a problem as he describes since the transfer was based on status of a patient's respiratory disease and was not related to the severity of the patient's eye disease. In fact,...
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References (2)

Publisher
American Medical Association
Copyright
Copyright © 1987 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1987.04460110019006
Publisher site
See Article on Publisher Site

Abstract

Abstract In Reply.—We appreciate Dr Brown's interest in our recent report. We are aware of the problems raised by him, problems that occur in any retrospective clinical study and for which there are no completely adequate solutions. The problem of transfer bias does not seem to us to be as severe a problem as he describes since the transfer was based on status of a patient's respiratory disease and was not related to the severity of the patient's eye disease. In fact, transfer occurred before eye disease status was known. In addition, transfer decisions were made in a reasonably uniform manner for all patients. The question of the appropriate number of df for the t test raises the question of how to handle an imperfect data set. Our system of obtaining weighted average values for each of the 92 patients was an attempt to make the most appropriate use we References 1. Brown DR, Milley JR, Ripepi UJ, et al: Retinopathy of prematurity: Risk factors in a five-year cohort of critically ill premature neonates . AJDC 1987;141:154-160.

Journal

American Journal of Diseases of Children – American Medical Association

Published: Nov 1, 1987

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